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The map label for this gene is 226948192

Identifier: 226948192

GI number: 226948192

Start: 1117179

End: 1117826

Strand: Direct

Name: 226948192

Synonym: CLM_1067

Alternate gene names: NA

Gene position: 1117179-1117826 (Clockwise)

Preceding gene: 226948191

Following gene: 226948193

Centisome position: 26.89

GC content: 25.93

Gene sequence:

>648_bases
TTGCAGGAAAAATATAATTTTATTGCTTTAAAGTCTAGAAGAATAAGAATATTAATAGTAGGAGGCGGAAGGGCAGCTTT
TATAAAAGGAAAAGCTTTTTTAGATAGAGGATGTAGTTTATATATACTAGCTCCTAAGTTTTCAAAGGGCGTATTAGATT
TAAAAACCTATGATAATGTAGAATTTATAAAAAATAATTATGATGAAAAATACATATTAGATAAGCATTTAGTTGTTATA
GCCACAGAAGATGAAGAAGTAAATAATGAAATAAGAAATAATTGTGACTCATTGAGTAAACTATACATAGATTGTTCTGA
TAAAGATAAAAGCCTATGTTTTAACAGTTTTCAAAGGGAAAGTAAAACTATGGTGTTAGCTTTAAATAATAAAATAGGTT
GTCCAAAAGCTACTTCTTTTATAGGAGAAAAAATAAAAAAAGACTTAGAAAGATATGATAATTATATAGAATATGTAACA
TATATAAGAAGCATCACAAAAAATAATTCTATGAAAGATGAAATTATAGATTTTATCTGCAGCAATGATTTTCACTTCTT
TTTTGAAAAGGGGTATGGTAATCTAATCTTATCAATGTTTTATGGAGGTATGGATTTTGAATTTTGTAATAGCCACACGA
AGAAGTAA

Upstream 100 bases:

>100_bases
GGAAAAACAACGATTTAAGATTATTATAAATACTTTATATTATGATTCTTTAGTATATTAAATTTAAATTATAGAAGATG
AAATTTTGGAGTGGATAAAT

Downstream 100 bases:

>100_bases
GCTTGCTCAGGTGCAAACAGAAATAATAATAGATTTATTAAATAAAAAGCATGATATAGAATGTGAAAAATTATTAATAG
AAACCGTAGGAGATAAAATA

Product: precorrin-2 dehydrogenase

Products: sirohydrochlorin; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MQEKYNFIALKSRRIRILIVGGGRAAFIKGKAFLDRGCSLYILAPKFSKGVLDLKTYDNVEFIKNNYDEKYILDKHLVVI
ATEDEEVNNEIRNNCDSLSKLYIDCSDKDKSLCFNSFQRESKTMVLALNNKIGCPKATSFIGEKIKKDLERYDNYIEYVT
YIRSITKNNSMKDEIIDFICSNDFHFFFEKGYGNLILSMFYGGMDFEFCNSHTKK

Sequences:

>Translated_215_residues
MQEKYNFIALKSRRIRILIVGGGRAAFIKGKAFLDRGCSLYILAPKFSKGVLDLKTYDNVEFIKNNYDEKYILDKHLVVI
ATEDEEVNNEIRNNCDSLSKLYIDCSDKDKSLCFNSFQRESKTMVLALNNKIGCPKATSFIGEKIKKDLERYDNYIEYVT
YIRSITKNNSMKDEIIDFICSNDFHFFFEKGYGNLILSMFYGGMDFEFCNSHTKK
>Mature_215_residues
MQEKYNFIALKSRRIRILIVGGGRAAFIKGKAFLDRGCSLYILAPKFSKGVLDLKTYDNVEFIKNNYDEKYILDKHLVVI
ATEDEEVNNEIRNNCDSLSKLYIDCSDKDKSLCFNSFQRESKTMVLALNNKIGCPKATSFIGEKIKKDLERYDNYIEYVT
YIRSITKNNSMKDEIIDFICSNDFHFFFEKGYGNLILSMFYGGMDFEFCNSHTKK

Specific function: Unknown

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.3.1.76; 4.99.1.4

Molecular weight: Translated: 25002; Mature: 25002

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKYNFIALKSRRIRILIVGGGRAAFIKGKAFLDRGCSLYILAPKFSKGVLDLKTYDNV
CCCCCEEEEEECCEEEEEEEECCEEEEEECHHHHHCCCEEEEECCCCCCCEEEEECCCCH
EFIKNNYDEKYILDKHLVVIATEDEEVNNEIRNNCDSLSKLYIDCSDKDKSLCFNSFQRE
HHHHCCCCCEEEECCEEEEEEECCHHHHHHHHHCHHHHHEEEEECCCCCHHHHHHHHHCC
SKTMVLALNNKIGCPKATSFIGEKIKKDLERYDNYIEYVTYIRSITKNNSMKDEIIDFIC
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SNDFHFFFEKGYGNLILSMFYGGMDFEFCNSHTKK
CCCCEEEEECCCHHHHHHHHHCCCCHHHHCCCCCC
>Mature Secondary Structure
MQEKYNFIALKSRRIRILIVGGGRAAFIKGKAFLDRGCSLYILAPKFSKGVLDLKTYDNV
CCCCCEEEEEECCEEEEEEEECCEEEEEECHHHHHCCCEEEEECCCCCCCEEEEECCCCH
EFIKNNYDEKYILDKHLVVIATEDEEVNNEIRNNCDSLSKLYIDCSDKDKSLCFNSFQRE
HHHHCCCCCEEEECCEEEEEEECCHHHHHHHHHCHHHHHEEEEECCCCCHHHHHHHHHCC
SKTMVLALNNKIGCPKATSFIGEKIKKDLERYDNYIEYVTYIRSITKNNSMKDEIIDFIC
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SNDFHFFFEKGYGNLILSMFYGGMDFEFCNSHTKK
CCCCEEEEECCCHHHHHHHHHCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 2; NAD+

Specific reaction: precorrin-2 + NAD+ = sirohydrochlorin + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA