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The map label for this gene is yeiE [H]

Identifier: 226948138

GI number: 226948138

Start: 1063077

End: 1063964

Strand: Direct

Name: yeiE [H]

Synonym: CLM_1006

Alternate gene names: 226948138

Gene position: 1063077-1063964 (Clockwise)

Preceding gene: 226948134

Following gene: 226948139

Centisome position: 25.58

GC content: 29.05

Gene sequence:

>888_bases
ATGTATATTAATCTTGAACTTTACAGAATTTTTTATATTACTGCCAAATTAGGCAGTATATCTAAAGCAGCAAAAGAGCT
TTTTACATCACAGCCAGCAGTTAGCCAATCTATAAAATTATTAGAAGGAAAATTAGGTGGGGAATTATTTCATAGAACTC
CAAGAGGAGTTTCACTTACCTTAGAAGGTGAGGTATTATTCAAATATATAGAGCAAGGTTATGGTCTTATGATGACAGCA
GAAAGAAAATTTTCAGAATTAAAAAATCTTAATTCAGGTCAGATAAGAATAGCTGTATGTAGTGCAGTATGCAAATACTA
TCTAATGAAATACATAGAAACTTATAATCTAAATTATCCACATATAAAAATTTATGTTAAGGATAAGTCAAGCTATGAAA
TAGCAAAAGCATTAGATTCAGGTGAGATAGATATAGGAATTTTAAATATGAATATAGACACAAGTAATTCTTTAAATGTC
ATTAAAGCATTTAAAATACAAGATTGCTTTGTGGTAGGAGAGAAATACAAGGAAATTTGTGAAAAACAGATAACATTGAA
GGAGTTAGTGGATAGATATCCTATTATTTTACTAGAGAAAGGTGGCAATACAAGGGGTTATATAGATAATTATTTTAGTT
CACATGGATTGGACATAATACCGCAAATAGAGTTAAGTAATGTAGAACTAATGATAGAATTTGCAAAAAGAGGCTTAGGA
GTTTCCTGTGTTATAAAAGATTATATCAAAAAGGAATTAGAGCAGAAACAATTATATGAAATATCTATTAAAGAAAAAAT
CCCAGAGAGAATTATGGGTATAGCAACTAAAAAAGATATTCCTATGTCTACAGCAGCTGAGAGATTTATTGATCTTATTG
GAGATTAG

Upstream 100 bases:

>100_bases
ATGCTTTTAATTGTTGAATAACTTTTATAAAGCAATTATAATTAATATACTGATATAAGTAAAATTAATATCTAGTATAG
GAGGTATACTAAATTTTTAT

Downstream 100 bases:

>100_bases
ATTATCTATTTGAATTTTATCTTTAGAATATGATATGCTAGTTTTTTATATTGAATATAATTAATATTAAAATTTGGTAT
TGCTATTAAATTATTTAGGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MYINLELYRIFYITAKLGSISKAAKELFTSQPAVSQSIKLLEGKLGGELFHRTPRGVSLTLEGEVLFKYIEQGYGLMMTA
ERKFSELKNLNSGQIRIAVCSAVCKYYLMKYIETYNLNYPHIKIYVKDKSSYEIAKALDSGEIDIGILNMNIDTSNSLNV
IKAFKIQDCFVVGEKYKEICEKQITLKELVDRYPIILLEKGGNTRGYIDNYFSSHGLDIIPQIELSNVELMIEFAKRGLG
VSCVIKDYIKKELEQKQLYEISIKEKIPERIMGIATKKDIPMSTAAERFIDLIGD

Sequences:

>Translated_295_residues
MYINLELYRIFYITAKLGSISKAAKELFTSQPAVSQSIKLLEGKLGGELFHRTPRGVSLTLEGEVLFKYIEQGYGLMMTA
ERKFSELKNLNSGQIRIAVCSAVCKYYLMKYIETYNLNYPHIKIYVKDKSSYEIAKALDSGEIDIGILNMNIDTSNSLNV
IKAFKIQDCFVVGEKYKEICEKQITLKELVDRYPIILLEKGGNTRGYIDNYFSSHGLDIIPQIELSNVELMIEFAKRGLG
VSCVIKDYIKKELEQKQLYEISIKEKIPERIMGIATKKDIPMSTAAERFIDLIGD
>Mature_295_residues
MYINLELYRIFYITAKLGSISKAAKELFTSQPAVSQSIKLLEGKLGGELFHRTPRGVSLTLEGEVLFKYIEQGYGLMMTA
ERKFSELKNLNSGQIRIAVCSAVCKYYLMKYIETYNLNYPHIKIYVKDKSSYEIAKALDSGEIDIGILNMNIDTSNSLNV
IKAFKIQDCFVVGEKYKEICEKQITLKELVDRYPIILLEKGGNTRGYIDNYFSSHGLDIIPQIELSNVELMIEFAKRGLG
VSCVIKDYIKKELEQKQLYEISIKEKIPERIMGIATKKDIPMSTAAERFIDLIGD

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=285, Percent_Identity=28.0701754385965, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=28.135593220339, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788296, Length=238, Percent_Identity=28.1512605042017, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI145693105, Length=290, Percent_Identity=25.8620689655172, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87081904, Length=294, Percent_Identity=25.1700680272109, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787530, Length=229, Percent_Identity=23.5807860262009, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=26.3888888888889, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788748, Length=303, Percent_Identity=23.1023102310231, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787879, Length=296, Percent_Identity=24.6621621621622, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789173, Length=137, Percent_Identity=30.6569343065693, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789204, Length=246, Percent_Identity=22.7642276422764, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790399, Length=272, Percent_Identity=20.5882352941176, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=22.7642276422764, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787128, Length=143, Percent_Identity=28.6713286713287, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33612; Mature: 33612

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYINLELYRIFYITAKLGSISKAAKELFTSQPAVSQSIKLLEGKLGGELFHRTPRGVSLT
CEEEEEEEEEEEEEHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCEEEE
LEGEVLFKYIEQGYGLMMTAERKFSELKNLNSGQIRIAVCSAVCKYYLMKYIETYNLNYP
ECHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCC
HIKIYVKDKSSYEIAKALDSGEIDIGILNMNIDTSNSLNVIKAFKIQDCFVVGEKYKEIC
EEEEEEECCCCHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEEEEEHHHEEECHHHHHHH
EKQITLKELVDRYPIILLEKGGNTRGYIDNYFSSHGLDIIPQIELSNVELMIEFAKRGLG
HHCCHHHHHHHHCCEEEEECCCCCCCCHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCC
VSCVIKDYIKKELEQKQLYEISIKEKIPERIMGIATKKDIPMSTAAERFIDLIGD
EEHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MYINLELYRIFYITAKLGSISKAAKELFTSQPAVSQSIKLLEGKLGGELFHRTPRGVSLT
CEEEEEEEEEEEEEHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCEEEE
LEGEVLFKYIEQGYGLMMTAERKFSELKNLNSGQIRIAVCSAVCKYYLMKYIETYNLNYP
ECHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCC
HIKIYVKDKSSYEIAKALDSGEIDIGILNMNIDTSNSLNVIKAFKIQDCFVVGEKYKEIC
EEEEEEECCCCHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEEEEEHHHEEECHHHHHHH
EKQITLKELVDRYPIILLEKGGNTRGYIDNYFSSHGLDIIPQIELSNVELMIEFAKRGLG
HHCCHHHHHHHHCCEEEEECCCCCCCCHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCC
VSCVIKDYIKKELEQKQLYEISIKEKIPERIMGIATKKDIPMSTAAERFIDLIGD
EEHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]