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The map label for this gene is hbpA [H]

Identifier: 226948093

GI number: 226948093

Start: 1016718

End: 1019198

Strand: Reverse

Name: hbpA [H]

Synonym: CLM_0956

Alternate gene names: 226948093

Gene position: 1019198-1016718 (Counterclockwise)

Preceding gene: 226948116

Following gene: 226948086

Centisome position: 24.53

GC content: 26.88

Gene sequence:

>2481_bases
ATGTTTAATTTTAAATTAAAAAGATCTTCCATAGATAAAAATATTAATAGCTTAAATGAAAAAAATATAGAAAAGCCCTG
TAATATTACAATCTATGAAGATAACTTAAAAATTCTAACTAATAATCAAAAAAAAATAGTAGACAAACTTGATAAAAAAA
TAATAGAAACAGATTCTGTTACAGAATTGTTAATTAAAATGACAAAGGATATATCTAATTACGTAGAAATGGAAATGGAT
TCTATATCTAAAGTTACAGGAGAAATAAGTAACTATTCTGCCATAGCTGAGGAGGTTTTTTCTAGTACAGAAAATTCAAA
GCAAATATCAGAAAGTACTATGGAAGTTGCTAAAGAAGGTAATGGAGCTGCTTTAAATTCCATAGAGGCTATGAAAGAAA
TAGAAGGATCTATGTTATATTCTAAAACAGTAGTAAAGGATTTAAGTACTAAAGCTTTAGATATTAACAATATGCTAGAT
GTAATAAAAGATATTGCAAACAATACTAATTTATTATCTTTAAATGCCTCTATTGAAGCTGCAAGGGCTGGTGAGGCTGG
TAAAGGCTTCGCAGTAGTTGCACATGAAGTAAAAAAACTAGCAGAAAGAAGTATGGATTCCGTTGATTTTATAGGAAATA
ATATAAAAGAAATAAATATTAGCATAGACAATGCTATAAGGGCTATAAATGAAACTATGAATAAAGTAAAAGAAGGTACC
GAAATAGCTAATAAAACTATGGAAACCTTCAACAGCATAATATCTTCTATAAAAACCAGTACCTCTGTATCTGAAGAAAT
TAATGATGCTATTACAAAACAAATTGGCCATTTAGAAAACGTAATTAACTCTACTGAAGAGATGAATACTACTTCTGAAA
AGTTAATGTTTATAGTAGAATTAGCTTCTTTAAATACTCAATATACAAAAACTTCTTTAAAGGATTTATCTGAGGTTTCC
CAAAACTTAAAATATATTAGTAATAATCTTTTAAATGAAATAGAAGTTGATTCTAAAGAAAATAATGTAATTTTAAATAC
TTATATTAATGGTAGACCTCTATATTTAGACCCTGCTTTAAGCTATGAACTTAATAGTAGCCTTCTATTAAATAATATAC
ATATAGGTCTTTTAACCATAAACTCCTATGGAGAAATATCTCCTGGAATAGCTAAAAGTTGGTATTTAGAAAAGGATAAC
CTTACTTGGGTTTTTAATCTTAAAAAAGGAATAAAATTTCATAATGGTAAAGAGGTTACCTCAGAAGATGTAAAATTTTC
ATTAGAAAGACTTTTAGATCCTAAACTTGACTCTCCTAACGGTTGGTTACTAGAAATTATAGAAGGATCTGAAGATTTTA
AAAAAGGTGCAGCAAAACATGTTTCTGGCATTAAGATATTGGATAAATATAGAATTTCTTTAACTTTATCCTATTCATAC
AGTGGATTTTTATTAAATCTTGGATTAGAACTTTGCGGCATAATAAATAAGGATTCTATAAATCAGGGGGATGTAGTAGG
CTGTGGCCCTTATAAAATATCTGAATTTAATGATGAAGGATGCAAACTAGAGGCCTTCAAAGAATATTTTAATGGAGCCC
CTTATATTGATATTATAAATATTAATTTTAAATCTGAATCTCCTATAGATGATTTCTTAAATGAAGATTTAGATGTATTA
ACCATAAATGATAAAAACGAATATACAACTTTATGTTCTAATAAAAATATAAATCTTATAGAACAAGATCTGCTAGCAAC
TTACTATGCTAGTTTTAACATGAAATCTAACTCTATTTTTTCTAGGGATAAAGATGTAAGAAATGCTCTTAACTTAGCCA
TAGACAAGAATAGAATAATAAAGGATATATTAGGTGGATTAGGAGTTGAAGCAAAGGGTCCTTTCCCTCCAAGCATAATA
CCTAATAATAAGTTAAGAGGTTTTTCTCATAATAAATCTAAAGCCAAAGAAATTCTTTCTAGAAGTGATTTTAATAGATC
TCGAGATAAATTAAATATATTAATCCGAAAGGATGAGGATTCTTTATTTTCTAAGATAACAGAATATATATTAGAAGATT
TAAAAAATATAGGAATAGATTGTATTGTAAAAGAAGTAAATTCTTCTGAATACTTAAACTTAGATAATATTTTAAAATGT
GACATGGCTATAAGCAGATGGTGCGCTGATTCTGGAGATCCTGATAATTTCTTAGAACCAATATTTAATATAGAAAATGT
GTCTAACATATCTAGGTATGACAATAAACTAGTAAATGAAAAATTAAAAAAAGCTAAAAACTTAATTAATCCTGAAAAAA
GGAAAAAATTATATGAAGAAATACAGGAAATTATAGTAGAGGATGTTCCATGGATATTTTTATATCATCCTAAACTAGCT
ATAGCAGTACAAAATAATATACTTGGATTGAATGCTAATCCTTTAGGACTTTTCAAATATGAAGATATAATAAAAAATTA
G

Upstream 100 bases:

>100_bases
TTTTAAAAATTATATTTAAATGAATATTTTTCATACTTTAACAAATTATTTAAATGAGTTAAAATGTTGGTAGTAACTAT
TATTTTATAGGGGGATTGAA

Downstream 100 bases:

>100_bases
ATACCTCATATTTTTATCTTGTGAAAAGGGTTGTCTCAAAATAGATTTAATTTTGAGACAACTTTTAGTTTTATTATATT
AAAAATCCGCTGCTTGTGGA

Product: methyl-accepting chemotaxis protein/ family 5 extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 826; Mature: 826

Protein sequence:

>826_residues
MFNFKLKRSSIDKNINSLNEKNIEKPCNITIYEDNLKILTNNQKKIVDKLDKKIIETDSVTELLIKMTKDISNYVEMEMD
SISKVTGEISNYSAIAEEVFSSTENSKQISESTMEVAKEGNGAALNSIEAMKEIEGSMLYSKTVVKDLSTKALDINNMLD
VIKDIANNTNLLSLNASIEAARAGEAGKGFAVVAHEVKKLAERSMDSVDFIGNNIKEINISIDNAIRAINETMNKVKEGT
EIANKTMETFNSIISSIKTSTSVSEEINDAITKQIGHLENVINSTEEMNTTSEKLMFIVELASLNTQYTKTSLKDLSEVS
QNLKYISNNLLNEIEVDSKENNVILNTYINGRPLYLDPALSYELNSSLLLNNIHIGLLTINSYGEISPGIAKSWYLEKDN
LTWVFNLKKGIKFHNGKEVTSEDVKFSLERLLDPKLDSPNGWLLEIIEGSEDFKKGAAKHVSGIKILDKYRISLTLSYSY
SGFLLNLGLELCGIINKDSINQGDVVGCGPYKISEFNDEGCKLEAFKEYFNGAPYIDIININFKSESPIDDFLNEDLDVL
TINDKNEYTTLCSNKNINLIEQDLLATYYASFNMKSNSIFSRDKDVRNALNLAIDKNRIIKDILGGLGVEAKGPFPPSII
PNNKLRGFSHNKSKAKEILSRSDFNRSRDKLNILIRKDEDSLFSKITEYILEDLKNIGIDCIVKEVNSSEYLNLDNILKC
DMAISRWCADSGDPDNFLEPIFNIENVSNISRYDNKLVNEKLKKAKNLINPEKRKKLYEEIQEIIVEDVPWIFLYHPKLA
IAVQNNILGLNANPLGLFKYEDIIKN

Sequences:

>Translated_826_residues
MFNFKLKRSSIDKNINSLNEKNIEKPCNITIYEDNLKILTNNQKKIVDKLDKKIIETDSVTELLIKMTKDISNYVEMEMD
SISKVTGEISNYSAIAEEVFSSTENSKQISESTMEVAKEGNGAALNSIEAMKEIEGSMLYSKTVVKDLSTKALDINNMLD
VIKDIANNTNLLSLNASIEAARAGEAGKGFAVVAHEVKKLAERSMDSVDFIGNNIKEINISIDNAIRAINETMNKVKEGT
EIANKTMETFNSIISSIKTSTSVSEEINDAITKQIGHLENVINSTEEMNTTSEKLMFIVELASLNTQYTKTSLKDLSEVS
QNLKYISNNLLNEIEVDSKENNVILNTYINGRPLYLDPALSYELNSSLLLNNIHIGLLTINSYGEISPGIAKSWYLEKDN
LTWVFNLKKGIKFHNGKEVTSEDVKFSLERLLDPKLDSPNGWLLEIIEGSEDFKKGAAKHVSGIKILDKYRISLTLSYSY
SGFLLNLGLELCGIINKDSINQGDVVGCGPYKISEFNDEGCKLEAFKEYFNGAPYIDIININFKSESPIDDFLNEDLDVL
TINDKNEYTTLCSNKNINLIEQDLLATYYASFNMKSNSIFSRDKDVRNALNLAIDKNRIIKDILGGLGVEAKGPFPPSII
PNNKLRGFSHNKSKAKEILSRSDFNRSRDKLNILIRKDEDSLFSKITEYILEDLKNIGIDCIVKEVNSSEYLNLDNILKC
DMAISRWCADSGDPDNFLEPIFNIENVSNISRYDNKLVNEKLKKAKNLINPEKRKKLYEEIQEIIVEDVPWIFLYHPKLA
IAVQNNILGLNANPLGLFKYEDIIKN
>Mature_826_residues
MFNFKLKRSSIDKNINSLNEKNIEKPCNITIYEDNLKILTNNQKKIVDKLDKKIIETDSVTELLIKMTKDISNYVEMEMD
SISKVTGEISNYSAIAEEVFSSTENSKQISESTMEVAKEGNGAALNSIEAMKEIEGSMLYSKTVVKDLSTKALDINNMLD
VIKDIANNTNLLSLNASIEAARAGEAGKGFAVVAHEVKKLAERSMDSVDFIGNNIKEINISIDNAIRAINETMNKVKEGT
EIANKTMETFNSIISSIKTSTSVSEEINDAITKQIGHLENVINSTEEMNTTSEKLMFIVELASLNTQYTKTSLKDLSEVS
QNLKYISNNLLNEIEVDSKENNVILNTYINGRPLYLDPALSYELNSSLLLNNIHIGLLTINSYGEISPGIAKSWYLEKDN
LTWVFNLKKGIKFHNGKEVTSEDVKFSLERLLDPKLDSPNGWLLEIIEGSEDFKKGAAKHVSGIKILDKYRISLTLSYSY
SGFLLNLGLELCGIINKDSINQGDVVGCGPYKISEFNDEGCKLEAFKEYFNGAPYIDIININFKSESPIDDFLNEDLDVL
TINDKNEYTTLCSNKNINLIEQDLLATYYASFNMKSNSIFSRDKDVRNALNLAIDKNRIIKDILGGLGVEAKGPFPPSII
PNNKLRGFSHNKSKAKEILSRSDFNRSRDKLNILIRKDEDSLFSKITEYILEDLKNIGIDCIVKEVNSSEYLNLDNILKC
DMAISRWCADSGDPDNFLEPIFNIENVSNISRYDNKLVNEKLKKAKNLINPEKRKKLYEEIQEIIVEDVPWIFLYHPKLA
IAVQNNILGLNANPLGLFKYEDIIKN

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=509, Percent_Identity=24.3614931237721, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI1787052, Length=496, Percent_Identity=24.7983870967742, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI87081878, Length=478, Percent_Identity=25.3138075313808, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1787762, Length=489, Percent_Identity=23.5173824130879, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1787551, Length=472, Percent_Identity=22.8813559322034, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788194, Length=305, Percent_Identity=26.2295081967213, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1789453, Length=240, Percent_Identity=26.6666666666667, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787495, Length=466, Percent_Identity=23.3905579399142, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI2367378, Length=228, Percent_Identity=29.3859649122807, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788195, Length=270, Percent_Identity=25.5555555555556, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1787690, Length=163, Percent_Identity=37.4233128834356, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789887, Length=461, Percent_Identity=22.9934924078091, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 92981; Mature: 92981

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01040 SBP_BACTERIAL_5 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNFKLKRSSIDKNINSLNEKNIEKPCNITIYEDNLKILTNNQKKIVDKLDKKIIETDSV
CCCEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCHHHHHHHHHHHHHCCCHH
TELLIKMTKDISNYVEMEMDSISKVTGEISNYSAIAEEVFSSTENSKQISESTMEVAKEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
NGAALNSIEAMKEIEGSMLYSKTVVKDLSTKALDINNMLDVIKDIANNTNLLSLNASIEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCH
ARAGEAGKGFAVVAHEVKKLAERSMDSVDFIGNNIKEINISIDNAIRAINETMNKVKEGT
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
EIANKTMETFNSIISSIKTSTSVSEEINDAITKQIGHLENVINSTEEMNTTSEKLMFIVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEH
LASLNTQYTKTSLKDLSEVSQNLKYISNNLLNEIEVDSKENNVILNTYINGRPLYLDPAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEECCEEEEECCCC
SYELNSSLLLNNIHIGLLTINSYGEISPGIAKSWYLEKDNLTWVFNLKKGIKFHNGKEVT
CCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCEEEECCCEEEEEEECCCCEECCCCCCC
SEDVKFSLERLLDPKLDSPNGWLLEIIEGSEDFKKGAAKHVSGIKILDKYRISLTLSYSY
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEEEEEEEEECC
SGFLLNLGLELCGIINKDSINQGDVVGCGPYKISEFNDEGCKLEAFKEYFNGAPYIDIIN
CCHHHHCCHHHHCCCCCCCCCCCCEEECCCEEECCCCCCCCHHHHHHHHHCCCCEEEEEE
INFKSESPIDDFLNEDLDVLTINDKNEYTTLCSNKNINLIEQDLLATYYASFNMKSNSIF
EEECCCCCHHHHHCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHH
SRDKDVRNALNLAIDKNRIIKDILGGLGVEAKGPFPPSIIPNNKLRGFSHNKSKAKEILS
HCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RSDFNRSRDKLNILIRKDEDSLFSKITEYILEDLKNIGIDCIVKEVNSSEYLNLDNILKC
HCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHH
DMAISRWCADSGDPDNFLEPIFNIENVSNISRYDNKLVNEKLKKAKNLINPEKRKKLYEE
HHHHHHHHCCCCCCHHHHHHHHCHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IQEIIVEDVPWIFLYHPKLAIAVQNNILGLNANPLGLFKYEDIIKN
HHHHHHHCCCEEEEECCEEEEEEECCEEECCCCCCEEEEHHHHHCC
>Mature Secondary Structure
MFNFKLKRSSIDKNINSLNEKNIEKPCNITIYEDNLKILTNNQKKIVDKLDKKIIETDSV
CCCEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCHHHHHHHHHHHHHCCCHH
TELLIKMTKDISNYVEMEMDSISKVTGEISNYSAIAEEVFSSTENSKQISESTMEVAKEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
NGAALNSIEAMKEIEGSMLYSKTVVKDLSTKALDINNMLDVIKDIANNTNLLSLNASIEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCH
ARAGEAGKGFAVVAHEVKKLAERSMDSVDFIGNNIKEINISIDNAIRAINETMNKVKEGT
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
EIANKTMETFNSIISSIKTSTSVSEEINDAITKQIGHLENVINSTEEMNTTSEKLMFIVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEH
LASLNTQYTKTSLKDLSEVSQNLKYISNNLLNEIEVDSKENNVILNTYINGRPLYLDPAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEECCEEEEECCCC
SYELNSSLLLNNIHIGLLTINSYGEISPGIAKSWYLEKDNLTWVFNLKKGIKFHNGKEVT
CCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCEEEECCCEEEEEEECCCCEECCCCCCC
SEDVKFSLERLLDPKLDSPNGWLLEIIEGSEDFKKGAAKHVSGIKILDKYRISLTLSYSY
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEEEEEEEEECC
SGFLLNLGLELCGIINKDSINQGDVVGCGPYKISEFNDEGCKLEAFKEYFNGAPYIDIIN
CCHHHHCCHHHHCCCCCCCCCCCCEEECCCEEECCCCCCCCHHHHHHHHHCCCCEEEEEE
INFKSESPIDDFLNEDLDVLTINDKNEYTTLCSNKNINLIEQDLLATYYASFNMKSNSIF
EEECCCCCHHHHHCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHH
SRDKDVRNALNLAIDKNRIIKDILGGLGVEAKGPFPPSIIPNNKLRGFSHNKSKAKEILS
HCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RSDFNRSRDKLNILIRKDEDSLFSKITEYILEDLKNIGIDCIVKEVNSSEYLNLDNILKC
HCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHH
DMAISRWCADSGDPDNFLEPIFNIENVSNISRYDNKLVNEKLKKAKNLINPEKRKKLYEE
HHHHHHHHCCCCCCHHHHHHHHCHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IQEIIVEDVPWIFLYHPKLAIAVQNNILGLNANPLGLFKYEDIIKN
HHHHHHHCCCEEEEECCEEEEEEECCEEECCCCCCEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]