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The map label for this gene is 226948059

Identifier: 226948059

GI number: 226948059

Start: 978090

End: 979304

Strand: Direct

Name: 226948059

Synonym: CLM_0920

Alternate gene names: NA

Gene position: 978090-979304 (Clockwise)

Preceding gene: 226948058

Following gene: 226948060

Centisome position: 23.54

GC content: 28.07

Gene sequence:

>1215_bases
ATGAAATTGAAAAATTTATTTAAAAGAAGCTTATCTCTTTTATTTTCATTTATAATGATTTTCACATTGGTTTCAGGCTT
AAATGTAAAGGCATTTTCAGGGGATGAACCCAAACAAACTCTTAATGTAGCTTTATATGAATATGTTCCTGATCCTATAC
GTTTTAAAAAAGCAGTTGAAACTGAGTGGAATAAGAAAGAACCTAATATAAAACTTAATTTTGTAGATTGGGATTGTTAT
AGTGAGGATCCACCGAAAGATTTAGATGTATTTGTTTTTGATGCAATTTATTTATCTCATTTCGTAAAGGAAGGATATCT
ATCCGAAATTCCAGAAAAGGATATAAAAAATAAAGAAGATATTCTACCTTTCGCAATGGAAGGATGTACTATAAAGGGTT
CAGCTTATGCAATTCCTCAAATAATATGTACTAATCTCTTATTTAGTAGAAAAGGAGATTATGACATACAAAAAGTAAAT
TCTGTATTTGATTTATATGACAAGTTAGGAAAGTTCACATCGGAAGATATTATTCTTCCTAACAATAAAGGACTGTTAAT
AGATATGTCTGGAGGAACTAGTAAAGCTTGTATGTATCTAGATTCACTAATTGATACAACTCAAGAGTACACCAAATTTT
GTTCATTACCCAATTTAAATGAATTAAATAAAGATGCAATTGAAAGTTTAGTATTATTACAATCAATGGCTGGAAAAAGT
CAGGCTAATTACTGGCCAGAAAATAATGATTCATATATTCGAGCTAAATGGTTTATTAACGGAAAAGGGAGAGCTTATAT
AGGTTATACTGAAGCAATGTCCCAAATGAAAGAATTTGCAAATGATATTGATTTTAAGACAATTTCTTTATCAAAAAATT
CTAATATTCCTATTTTTTATGGAGATGTGGTTGGAATAAACTCTTCTATAACGAATCCATATAAGAAAGAAAAAGCAATT
GAGCTTGCTAATATTATTACAGACAAAAACACTATGGTGAAAGCAGTTTCTCCAGATGAAAATAATAAATATCCTCAATA
TTTATTACCTGCTAGAAGAAGTGTATATCATAATTTAGAAAATAAGTATCCTATTTATGGTAAATTATATAAAATAGCTG
ATAATTCTAATAATAAACTGTTTAGAACTGGCCCTGAAATACGTGAATGGTTAAAACAAGCAAAGAAAATTATTACTGAA
TATTTACAACAATGA

Upstream 100 bases:

>100_bases
TTGGGGGAGTGAAAAGAACAAGCCACCCTTTATTATATTCGATGTAGAAAAATAAGAAAATTTAAAGATAAATTACGTGT
ATAATGAAAGGAGTAAACCC

Downstream 100 bases:

>100_bases
TATAATAAATAATAATCATTGAAATTAAAGGTACTTTTATTATTAAAAGTGCCTTTTTGTAGAAGGGAGAAAAATTTATG
AAGAAAGTACTTAGTATTGC

Product: putative thiamine pyridinylase I

Products: NA

Alternate protein names: Thiaminase I; Thiamine pyridinylase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKLKNLFKRSLSLLFSFIMIFTLVSGLNVKAFSGDEPKQTLNVALYEYVPDPIRFKKAVETEWNKKEPNIKLNFVDWDCY
SEDPPKDLDVFVFDAIYLSHFVKEGYLSEIPEKDIKNKEDILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVN
SVFDLYDKLGKFTSEDIILPNNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKS
QANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFYGDVVGINSSITNPYKKEKAI
ELANIITDKNTMVKAVSPDENNKYPQYLLPARRSVYHNLENKYPIYGKLYKIADNSNNKLFRTGPEIREWLKQAKKIITE
YLQQ

Sequences:

>Translated_404_residues
MKLKNLFKRSLSLLFSFIMIFTLVSGLNVKAFSGDEPKQTLNVALYEYVPDPIRFKKAVETEWNKKEPNIKLNFVDWDCY
SEDPPKDLDVFVFDAIYLSHFVKEGYLSEIPEKDIKNKEDILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVN
SVFDLYDKLGKFTSEDIILPNNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKS
QANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFYGDVVGINSSITNPYKKEKAI
ELANIITDKNTMVKAVSPDENNKYPQYLLPARRSVYHNLENKYPIYGKLYKIADNSNNKLFRTGPEIREWLKQAKKIITE
YLQQ
>Mature_404_residues
MKLKNLFKRSLSLLFSFIMIFTLVSGLNVKAFSGDEPKQTLNVALYEYVPDPIRFKKAVETEWNKKEPNIKLNFVDWDCY
SEDPPKDLDVFVFDAIYLSHFVKEGYLSEIPEKDIKNKEDILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVN
SVFDLYDKLGKFTSEDIILPNNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKS
QANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFYGDVVGINSSITNPYKKEKAI
ELANIITDKNTMVKAVSPDENNKYPQYLLPARRSVYHNLENKYPIYGKLYKIADNSNNKLFRTGPEIREWLKQAKKIITE
YLQQ

Specific function: Degrades thiamine by replacing its thiazole moiety with a wide range of nucleophiles [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: =2.5.1.2 [H]

Molecular weight: Translated: 46370; Mature: 46370

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKNLFKRSLSLLFSFIMIFTLVSGLNVKAFSGDEPKQTLNVALYEYVPDPIRFKKAVE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHH
TEWNKKEPNIKLNFVDWDCYSEDPPKDLDVFVFDAIYLSHFVKEGYLSEIPEKDIKNKED
CCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHH
ILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVNSVFDLYDKLGKFTSEDIILP
CCCCHHCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
NNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKS
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
QANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFY
CCCCCCCCCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEE
GDVVGINSSITNPYKKEKAIELANIITDKNTMVKAVSPDENNKYPQYLLPARRSVYHNLE
CCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHC
NKYPIYGKLYKIADNSNNKLFRTGPEIREWLKQAKKIITEYLQQ
CCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLKNLFKRSLSLLFSFIMIFTLVSGLNVKAFSGDEPKQTLNVALYEYVPDPIRFKKAVE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHH
TEWNKKEPNIKLNFVDWDCYSEDPPKDLDVFVFDAIYLSHFVKEGYLSEIPEKDIKNKED
CCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHH
ILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVNSVFDLYDKLGKFTSEDIILP
CCCCHHCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
NNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKS
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
QANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFY
CCCCCCCCCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEE
GDVVGINSSITNPYKKEKAIELANIITDKNTMVKAVSPDENNKYPQYLLPARRSVYHNLE
CCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHC
NKYPIYGKLYKIADNSNNKLFRTGPEIREWLKQAKKIITEYLQQ
CCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8631946; 9843405 [H]