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The map label for this gene is fhuG [H]

Identifier: 226947947

GI number: 226947947

Start: 867523

End: 868563

Strand: Direct

Name: fhuG [H]

Synonym: CLM_0805

Alternate gene names: 226947947

Gene position: 867523-868563 (Clockwise)

Preceding gene: 226947946

Following gene: 226947948

Centisome position: 20.88

GC content: 36.5

Gene sequence:

>1041_bases
ATGAAAGAACAACAACAAATAATTGAAGCATATAAACGTAAGGTAGCCATTCGTAATACATTAATTGTAATTGGATGCAT
TTTATTACTAGCAATTTCTTTAATTATAAGTATGGATACAGGATATATTAAAATGTCTCCATTTGATGTTTTAAGAACTT
TATTTGGTAAAGGTACAGACAAAGAGAAGTTGATTTTATTTGATTTTAGGCTGCCTCGTATAGTTATTTCAATGTTAGTA
GGAGCTGGACTTGCTTTGTCAGGATGCATAATACAGAGTGTATCTAAAAATCCTCTAGCTGATCCAGGAATTTTAGGCAT
TAACGCCGGTGCTAGTTTAATGGTGATTTTATATGTATTGATCTTTAGTGCAGAATCTTTCCTATCCGTGTTTACTCTTC
CATTTTTAGCCTTAATAGGAGCCGGTGCTACAGCAGTTATAGTTTATCTTTTTTCTTATAAGCGGGATGAAGGTATCTCA
ACTATGAGGCTTGTTTTAACTGGTGTGGCAGTACAGGCAGGAATTTCAGCATTAACCACTTTACTGGTGGTGAAATTGGA
TGATACACAGTATAACTTTGTTGTTGCTTGGCAGGCAGGAAGTATTTGGGGATCTAACTGGAAGTTTGTGATGACATTAC
TGCCTTGGTTATTGATATTGATTCCATATATACTAACAAAATCTTCTGTTATGGATATACTGAATCTTAGTGATGATATA
GCCTATGGTCTCGGTGTTTCAGTAGAAAAAGAACGTCGCAAACTGCTTGCAGCGGCAGTAGCTCTTGCTGCCTCATGTGT
GGCAGTTAGTGGAAGCATTAGTTTTATTGGTCTTATAGCACCCCATTTATCAAGACGACTTGTGGGACCGCGACATGGTG
TACTTTTATCCACCAGTATACTGATTGGTGCTGTATTAGTATCTTTGGCAGATACTATTGGACGTGTTATCATTCAGCCT
TCTGAGATTCCAACAGGAATTGTAGTAGCTATTATTGGAGCGCCATATTTTCTTTATCTTCTTTCTAATAGTAAGAGTTG
A

Upstream 100 bases:

>100_bases
CTTTAAACCCTCCTTTTGAAACTCCCATAGGAGCTATAATTTCTCTTATTGGTGTACCATTATTTTTAAATTTGGCTCGT
AGGCAAAGGAGTGCAATATA

Downstream 100 bases:

>100_bases
TTATAGGATTGTTAATAAAAATAAATATAATATGCAAAAATTTTAATGGTATTAAATGCATTTGGAGTAAATTAGGTTTG
CAAAAATTTTAATAATATTA

Product: ferrichrome transport system permease FhuG

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKEQQQIIEAYKRKVAIRNTLIVIGCILLLAISLIISMDTGYIKMSPFDVLRTLFGKGTDKEKLILFDFRLPRIVISMLV
GAGLALSGCIIQSVSKNPLADPGILGINAGASLMVILYVLIFSAESFLSVFTLPFLALIGAGATAVIVYLFSYKRDEGIS
TMRLVLTGVAVQAGISALTTLLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLLILIPYILTKSSVMDILNLSDDI
AYGLGVSVEKERRKLLAAAVALAASCVAVSGSISFIGLIAPHLSRRLVGPRHGVLLSTSILIGAVLVSLADTIGRVIIQP
SEIPTGIVVAIIGAPYFLYLLSNSKS

Sequences:

>Translated_346_residues
MKEQQQIIEAYKRKVAIRNTLIVIGCILLLAISLIISMDTGYIKMSPFDVLRTLFGKGTDKEKLILFDFRLPRIVISMLV
GAGLALSGCIIQSVSKNPLADPGILGINAGASLMVILYVLIFSAESFLSVFTLPFLALIGAGATAVIVYLFSYKRDEGIS
TMRLVLTGVAVQAGISALTTLLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLLILIPYILTKSSVMDILNLSDDI
AYGLGVSVEKERRKLLAAAVALAASCVAVSGSISFIGLIAPHLSRRLVGPRHGVLLSTSILIGAVLVSLADTIGRVIIQP
SEIPTGIVVAIIGAPYFLYLLSNSKS
>Mature_346_residues
MKEQQQIIEAYKRKVAIRNTLIVIGCILLLAISLIISMDTGYIKMSPFDVLRTLFGKGTDKEKLILFDFRLPRIVISMLV
GAGLALSGCIIQSVSKNPLADPGILGINAGASLMVILYVLIFSAESFLSVFTLPFLALIGAGATAVIVYLFSYKRDEGIS
TMRLVLTGVAVQAGISALTTLLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLLILIPYILTKSSVMDILNLSDDI
AYGLGVSVEKERRKLLAAAVALAASCVAVSGSISFIGLIAPHLSRRLVGPRHGVLLSTSILIGAVLVSLADTIGRVIIQP
SEIPTGIVVAIIGAPYFLYLLSNSKS

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=326, Percent_Identity=38.0368098159509, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1790741, Length=303, Percent_Identity=33.3333333333333, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786804, Length=331, Percent_Identity=31.7220543806647, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1786805, Length=328, Percent_Identity=34.7560975609756, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=35.3146853146853, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786347, Length=286, Percent_Identity=32.8671328671329, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37142; Mature: 37142

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQQQIIEAYKRKVAIRNTLIVIGCILLLAISLIISMDTGYIKMSPFDVLRTLFGKGTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCC
KEKLILFDFRLPRIVISMLVGAGLALSGCIIQSVSKNPLADPGILGINAGASLMVILYVL
CCEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHH
IFSAESFLSVFTLPFLALIGAGATAVIVYLFSYKRDEGISTMRLVLTGVAVQAGISALTT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLLILIPYILTKSSVMDILNLSDDI
HHEEEECCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AYGLGVSVEKERRKLLAAAVALAASCVAVSGSISFIGLIAPHLSRRLVGPRHGVLLSTSI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LIGAVLVSLADTIGRVIIQPSEIPTGIVVAIIGAPYFLYLLSNSKS
HHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHCCCEEEEECCCCC
>Mature Secondary Structure
MKEQQQIIEAYKRKVAIRNTLIVIGCILLLAISLIISMDTGYIKMSPFDVLRTLFGKGTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCC
KEKLILFDFRLPRIVISMLVGAGLALSGCIIQSVSKNPLADPGILGINAGASLMVILYVL
CCEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHH
IFSAESFLSVFTLPFLALIGAGATAVIVYLFSYKRDEGISTMRLVLTGVAVQAGISALTT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLLILIPYILTKSSVMDILNLSDDI
HHEEEECCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AYGLGVSVEKERRKLLAAAVALAASCVAVSGSISFIGLIAPHLSRRLVGPRHGVLLSTSI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LIGAVLVSLADTIGRVIIQPSEIPTGIVVAIIGAPYFLYLLSNSKS
HHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]