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The map label for this gene is 226947710

Identifier: 226947710

GI number: 226947710

Start: 603443

End: 603991

Strand: Direct

Name: 226947710

Synonym: CLM_0557

Alternate gene names: NA

Gene position: 603443-603991 (Clockwise)

Preceding gene: 226947709

Following gene: 226947711

Centisome position: 14.52

GC content: 31.15

Gene sequence:

>549_bases
ATGAAGAAATTAGAAGAGAAAATATTATATGAAGGTAAATGGATAAGTTTTAAGGAAATAAGTTATTTAAATAATGAAGA
AAAGCTTTTAAAATGGGAAGCAGTAGAGAGAACCAATACGACTAAAGCTGTGGTTATTGTGGCAAAATTAGTTCCAACAG
AGCGATATGTATTTATAAAACAATATAGACCAGCTATAGATAATTATGTTATAGGATTTCCTGCTGGATTATTAGAACAA
GAAGATGTTGAAGCAGAGGCTAAAAGAGAATTAAAAGAAGAAACAGGCTATGTGGGTAGGGTTATAGACATAAGTCCAGA
GATAAGACCTAACCCAGCTTTATTAACAGATTACACTATATTAGTTCAAATGGAGATTGATGAAAATGATGAATTAAATA
AAAATCCCCAGCAAGAACTAGAACCTTCAGAGGATATAGAGGTCATGTTAGTGTCTAAAGAAGAAAGTAGAGACTTTTTA
ATAGAACAAAAAAATAATGGAGTAGATGTGGGAGTAGGTCCTTGGTACATATTTGGATTTAAATTGTAA

Upstream 100 bases:

>100_bases
ACCAATAAAGCTTATAGTAGATCCTGCGGTACCAGGAGAGGGTGGAAGTAAAATAAAAATAGAGTATAGCTAGTAGTAGA
TAATTTATGGAGGTAATTAG

Downstream 100 bases:

>100_bases
TTAATTTTTTATTAAAATAATATAATTTTGTTTTTTATTTAAATAGAGGAAATAAGATGTTTCAAAATAAAATTTATTTT
GAAACATCTTATTTTTTTTG

Product: NUDIX family hydrolase

Products: AMP; D-ribose 5-phosphate

Alternate protein names: MutT/Nudix Family Protein; Hydrolase; MutT/NUDIX Family Hydrolase; Hydrolase NUDIX Family

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKKLEEKILYEGKWISFKEISYLNNEEKLLKWEAVERTNTTKAVVIVAKLVPTERYVFIKQYRPAIDNYVIGFPAGLLEQ
EDVEAEAKRELKEETGYVGRVIDISPEIRPNPALLTDYTILVQMEIDENDELNKNPQQELEPSEDIEVMLVSKEESRDFL
IEQKNNGVDVGVGPWYIFGFKL

Sequences:

>Translated_182_residues
MKKLEEKILYEGKWISFKEISYLNNEEKLLKWEAVERTNTTKAVVIVAKLVPTERYVFIKQYRPAIDNYVIGFPAGLLEQ
EDVEAEAKRELKEETGYVGRVIDISPEIRPNPALLTDYTILVQMEIDENDELNKNPQQELEPSEDIEVMLVSKEESRDFL
IEQKNNGVDVGVGPWYIFGFKL
>Mature_182_residues
MKKLEEKILYEGKWISFKEISYLNNEEKLLKWEAVERTNTTKAVVIVAKLVPTERYVFIKQYRPAIDNYVIGFPAGLLEQ
EDVEAEAKRELKEETGYVGRVIDISPEIRPNPALLTDYTILVQMEIDENDELNKNPQQELEPSEDIEVMLVSKEESRDFL
IEQKNNGVDVGVGPWYIFGFKL

Specific function: Unknown

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI37594464, Length=190, Percent_Identity=32.6315789473684, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564994, Length=157, Percent_Identity=32.484076433121, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319587, Length=166, Percent_Identity=30.7228915662651, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.13

Molecular weight: Translated: 21128; Mature: 21128

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLEEKILYEGKWISFKEISYLNNEEKLLKWEAVERTNTTKAVVIVAKLVPTERYVFIK
CCCHHHHHHHCCCCCEEEHHHHCCCHHHEEEEEECCCCCCCEEEEEEEEECCCCEEEEEE
QYRPAIDNYVIGFPAGLLEQEDVEAEAKRELKEETGYVGRVIDISPEIRPNPALLTDYTI
ECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEE
LVQMEIDENDELNKNPQQELEPSEDIEVMLVSKEESRDFLIEQKNNGVDVGVGPWYIFGF
EEEEEECCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCEEEEECCCCEEECCCCEEEEEE
KL
EC
>Mature Secondary Structure
MKKLEEKILYEGKWISFKEISYLNNEEKLLKWEAVERTNTTKAVVIVAKLVPTERYVFIK
CCCHHHHHHHCCCCCEEEHHHHCCCHHHEEEEEECCCCCCCEEEEEEEEECCCCEEEEEE
QYRPAIDNYVIGFPAGLLEQEDVEAEAKRELKEETGYVGRVIDISPEIRPNPALLTDYTI
ECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEE
LVQMEIDENDELNKNPQQELEPSEDIEVMLVSKEESRDFLIEQKNNGVDVGVGPWYIFGF
EEEEEECCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCEEEEECCCCEEECCCCEEEEEE
KL
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADPribose; H2O

Specific reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA