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The map label for this gene is pepT [H]

Identifier: 226947674

GI number: 226947674

Start: 567124

End: 568350

Strand: Direct

Name: pepT [H]

Synonym: CLM_0520

Alternate gene names: 226947674

Gene position: 567124-568350 (Clockwise)

Preceding gene: 226947673

Following gene: 226947676

Centisome position: 13.65

GC content: 31.05

Gene sequence:

>1227_bases
ATGAAAGATGTATTAGAAAGATTCTTGGGGTATATAAAAGTAGATACCCAATCATCAGAGGAATCTGATACTGTACCAAC
TACTAAAACTCAATTAGAGTTTGCAAAAAAATTAGGAGAAGAATTAAAGGCTATAGGACTTAAAGATGTATCTGTAGATG
AAAACGGATATGTTATGGCTACTCTAGAATCAAACATAGATAAAAAAGTGCCTACAATTGGCTTTATAGCACATATGGAC
ACAAGTCCAGACTTATCAGGAACTAATATTAATCCTAGAATTGTAGAGAAATATGATGGACAAGATATAGTTTTAAACAA
AGAAAAAAACATAGTATTGAAGATTAATGAATTTCCAGAAATATTGGAATACAAGGGACAAGACATAGTGGTAACAGATG
GAAATACTCTTTTGGGAGCAGATGATAAAGCAGGAATAGCAGAGATAATTACGGCTATGGAATATCTAATAAATCATCCA
GAAATAAAACATGGAACTATAAAAGTTGGTTTTACTCCAGATGAAGAAGTGGGTAAAGGAGCAGATCACTTTGATGTTAA
AAAATTTGGAGCAGATTTAGCCTATACTTTAGATGGTGGCGGTATCGGAGAGTTAGAATGTGAAACTTTTAATGCTGCAA
AAGCTAAAGTTATTATAGAAGGAAGAAATGTTCATCCAGGTTCTGCAAAAAATAAAATGACAAATGCAGTATTAGTAGCT
AATAAGTTTATAAATATGCTTCCAGAAAATGAAGTTCCAGAAAGAACAGAAGGATATGAAGGATTTTTCCATCTATTATC
TGTAAAGAGTGAAGTAGAAACAGCAGAATTAAATTATATTATAAGAGATTTTGATAGAAAAAAATTTGAAGAAAGAAAAG
AACAAATAAAAGAAGTTGGTAAAAAAATAAATGAAGAATACAATAAAGAAATAGTATGTGTAAAAGTAGAAGACCAGTAT
TACAATATGAAAGAAAAAATAGATGAAGTAAAATATGTGGTAGATATAGCTCATGATGCTATGAAAGCTATTGATATTGA
ACCAATATTAGTGCCTATAAGAGGTGGTACAGATGGTTCAAGACTATCTTTTATGGGATTACCAACTCCAAATCTATTTG
CAGGTGGACATAATTTCCACGGAAGATTTGAGTTTGTTCCAGTTCTATCAATGGAAAAAGCAGCAGAACTTGTGGTTAAG
ATAGCTGAACTATATGCTAATAGATAA

Upstream 100 bases:

>100_bases
GGAGATGTTTGCATAGAAGAATAGTATATTGTAGAATATAAGTAAACAATTACAAAAAATATAAATAAAAACCAAAATTT
GTTTTAAAGGGGGATCATTA

Downstream 100 bases:

>100_bases
TAAGTTTTTTAAAATTTAGCATCGTTTTTATTAAATATAAAATATTCATAAAAAATGTCTTAAAATAAAAAGATTTAATT
TTAAGATTGCTAGAATATAA

Product: peptidase T

Products: NA

Alternate protein names: Aminotripeptidase; Tripeptidase; Tripeptide aminopeptidase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKDVLERFLGYIKVDTQSSEESDTVPTTKTQLEFAKKLGEELKAIGLKDVSVDENGYVMATLESNIDKKVPTIGFIAHMD
TSPDLSGTNINPRIVEKYDGQDIVLNKEKNIVLKINEFPEILEYKGQDIVVTDGNTLLGADDKAGIAEIITAMEYLINHP
EIKHGTIKVGFTPDEEVGKGADHFDVKKFGADLAYTLDGGGIGELECETFNAAKAKVIIEGRNVHPGSAKNKMTNAVLVA
NKFINMLPENEVPERTEGYEGFFHLLSVKSEVETAELNYIIRDFDRKKFEERKEQIKEVGKKINEEYNKEIVCVKVEDQY
YNMKEKIDEVKYVVDIAHDAMKAIDIEPILVPIRGGTDGSRLSFMGLPTPNLFAGGHNFHGRFEFVPVLSMEKAAELVVK
IAELYANR

Sequences:

>Translated_408_residues
MKDVLERFLGYIKVDTQSSEESDTVPTTKTQLEFAKKLGEELKAIGLKDVSVDENGYVMATLESNIDKKVPTIGFIAHMD
TSPDLSGTNINPRIVEKYDGQDIVLNKEKNIVLKINEFPEILEYKGQDIVVTDGNTLLGADDKAGIAEIITAMEYLINHP
EIKHGTIKVGFTPDEEVGKGADHFDVKKFGADLAYTLDGGGIGELECETFNAAKAKVIIEGRNVHPGSAKNKMTNAVLVA
NKFINMLPENEVPERTEGYEGFFHLLSVKSEVETAELNYIIRDFDRKKFEERKEQIKEVGKKINEEYNKEIVCVKVEDQY
YNMKEKIDEVKYVVDIAHDAMKAIDIEPILVPIRGGTDGSRLSFMGLPTPNLFAGGHNFHGRFEFVPVLSMEKAAELVVK
IAELYANR
>Mature_408_residues
MKDVLERFLGYIKVDTQSSEESDTVPTTKTQLEFAKKLGEELKAIGLKDVSVDENGYVMATLESNIDKKVPTIGFIAHMD
TSPDLSGTNINPRIVEKYDGQDIVLNKEKNIVLKINEFPEILEYKGQDIVVTDGNTLLGADDKAGIAEIITAMEYLINHP
EIKHGTIKVGFTPDEEVGKGADHFDVKKFGADLAYTLDGGGIGELECETFNAAKAKVIIEGRNVHPGSAKNKMTNAVLVA
NKFINMLPENEVPERTEGYEGFFHLLSVKSEVETAELNYIIRDFDRKKFEERKEQIKEVGKKINEEYNKEIVCVKVEDQY
YNMKEKIDEVKYVVDIAHDAMKAIDIEPILVPIRGGTDGSRLSFMGLPTPNLFAGGHNFHGRFEFVPVLSMEKAAELVVK
IAELYANR

Specific function: Cleaves the N-terminal amino acid of tripeptides [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20B family [H]

Homologues:

Organism=Escherichia coli, GI1787372, Length=409, Percent_Identity=53.3007334963325, Blast_Score=441, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010161 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.11.4 [H]

Molecular weight: Translated: 45583; Mature: 45583

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVLERFLGYIKVDTQSSEESDTVPTTKTQLEFAKKLGEELKAIGLKDVSVDENGYVMA
CHHHHHHHHCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEE
TLESNIDKKVPTIGFIAHMDTSPDLSGTNINPRIVEKYDGQDIVLNKEKNIVLKINEFPE
EECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEEECCCCEEEEECCCHH
ILEYKGQDIVVTDGNTLLGADDKAGIAEIITAMEYLINHPEIKHGTIKVGFTPDEEVGKG
HHHCCCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHCCC
ADHFDVKKFGADLAYTLDGGGIGELECETFNAAKAKVIIEGRNVHPGSAKNKMTNAVLVA
CCCCHHHHHCCCEEEEECCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
NKFINMLPENEVPERTEGYEGFFHLLSVKSEVETAELNYIIRDFDRKKFEERKEQIKEVG
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKINEEYNKEIVCVKVEDQYYNMKEKIDEVKYVVDIAHDAMKAIDIEPILVPIRGGTDGS
HHHHHHHCCCEEEEEECCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
RLSFMGLPTPNLFAGGHNFHGRFEFVPVLSMEKAAELVVKIAELYANR
EEEEEECCCCCEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDVLERFLGYIKVDTQSSEESDTVPTTKTQLEFAKKLGEELKAIGLKDVSVDENGYVMA
CHHHHHHHHCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEE
TLESNIDKKVPTIGFIAHMDTSPDLSGTNINPRIVEKYDGQDIVLNKEKNIVLKINEFPE
EECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEEECCCCEEEEECCCHH
ILEYKGQDIVVTDGNTLLGADDKAGIAEIITAMEYLINHPEIKHGTIKVGFTPDEEVGKG
HHHCCCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHCCC
ADHFDVKKFGADLAYTLDGGGIGELECETFNAAKAKVIIEGRNVHPGSAKNKMTNAVLVA
CCCCHHHHHCCCEEEEECCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
NKFINMLPENEVPERTEGYEGFFHLLSVKSEVETAELNYIIRDFDRKKFEERKEQIKEVG
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKINEEYNKEIVCVKVEDQYYNMKEKIDEVKYVVDIAHDAMKAIDIEPILVPIRGGTDGS
HHHHHHHCCCEEEEEECCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
RLSFMGLPTPNLFAGGHNFHGRFEFVPVLSMEKAAELVVKIAELYANR
EEEEEECCCCCEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA