Click here to switch to the map view.

The map label for this gene is manA [H]

Identifier: 226947646

GI number: 226947646

Start: 524339

End: 525319

Strand: Direct

Name: manA [H]

Synonym: CLM_0483

Alternate gene names: 226947646

Gene position: 524339-525319 (Clockwise)

Preceding gene: 226947643

Following gene: 226947647

Centisome position: 12.62

GC content: 27.12

Gene sequence:

>981_bases
ATGTACCCTTTAAAATTTGAAAACATATATTTAAATAAGGTGTGGGGGGGAAGAGGCTTAAAAAAATTTAGAGATAATCT
TCCTAAAGGTGATATAGGTGAAAGTTGGGATATAGCATTTAACCAAGATTTAATAAGTGTAATCAAAAATGGGAAACTTA
AGGGGAAGACATTAAAAGATGCTATAGAATTATATAAAAATAAATTAATGGGAGACTGCATATTTGATAAATATAAAGAT
TTTCCATTACTTTTAAAAATAATAAGTGCAGAAAAAAAATTGTCCATACAGGTACACCCAGGTGAAAAAGACATTTTAGA
TTTAAAGGAAAATCCTAAAAAAGAAGCCTGGTATGTTATGGAAGCTAAAGTGGGTTCCTATATAATTTTAGGTAGTAAAA
TAAAAGATAAAACTGTACTTAAACAGGTTATAGACGATGGCACAGTTGAAGATTATTTATATAAAGTACCAGTAAAGAAG
GGGGATATATTTTATATAGATAGTGGAATGATTCATGCTATAGGTAAAGGAGTTACATTAATTGAAATTCAACAGAACAG
CGATACAACTTATAGATTATATGATTATAATAGAGGAAGAAAACTAGATTTAGAAAAAGGAATGAATTGTGTAAATTTAG
ATATTAAACCTAATAAAAAATCAGGCTTAAAAGTGCAATTGAAAAATTGTAATAAAACTTATTGCTTTTTGTCAGAGGCT
TTTGCTATGGAAAAATATGAAGTATATTATTTCTTAAAAGAAAAAAGTGATAAAGAAAGATTTTTTATTTTTACCTGTGT
AGATGGACAAGGACAAATTAATTATGGTGAAGGACGACAAAATCTAAGTAGGGGAGATAGTATACTCATACCTGCTTATA
TGGGAGATTATACATTAAGAGGTAACATGAACTTATTGAAATTTTATATACCAGATATAGAAAAGTCCATTAATAGTATT
GTAAATATAATAAAATGTTAA

Upstream 100 bases:

>100_bases
AGGTGTGGGACAATAATCATTTATATATTTTTTATTTTAGAATATATATTAAATGTATCTAATATATATTAAGTGAATTA
ATTTATATTTAAGGAGAAAA

Downstream 100 bases:

>100_bases
ATAGATTTTATGTTATTAGATTAAAACAATAAAATTAAAAGAAGTATGTATTGTATAGAGAGAAATTTATAAATGATGTA
TAAATTAGGTTTGATTTTAG

Product: mannose-6-phosphate isomerase, class I

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFNQDLISVIKNGKLKGKTLKDAIELYKNKLMGDCIFDKYKD
FPLLLKIISAEKKLSIQVHPGEKDILDLKENPKKEAWYVMEAKVGSYIILGSKIKDKTVLKQVIDDGTVEDYLYKVPVKK
GDIFYIDSGMIHAIGKGVTLIEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPNKKSGLKVQLKNCNKTYCFLSEA
FAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYGEGRQNLSRGDSILIPAYMGDYTLRGNMNLLKFYIPDIEKSINSI
VNIIKC

Sequences:

>Translated_326_residues
MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFNQDLISVIKNGKLKGKTLKDAIELYKNKLMGDCIFDKYKD
FPLLLKIISAEKKLSIQVHPGEKDILDLKENPKKEAWYVMEAKVGSYIILGSKIKDKTVLKQVIDDGTVEDYLYKVPVKK
GDIFYIDSGMIHAIGKGVTLIEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPNKKSGLKVQLKNCNKTYCFLSEA
FAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYGEGRQNLSRGDSILIPAYMGDYTLRGNMNLLKFYIPDIEKSINSI
VNIIKC
>Mature_326_residues
MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFNQDLISVIKNGKLKGKTLKDAIELYKNKLMGDCIFDKYKD
FPLLLKIISAEKKLSIQVHPGEKDILDLKENPKKEAWYVMEAKVGSYIILGSKIKDKTVLKQVIDDGTVEDYLYKVPVKK
GDIFYIDSGMIHAIGKGVTLIEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPNKKSGLKVQLKNCNKTYCFLSEA
FAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYGEGRQNLSRGDSILIPAYMGDYTLRGNMNLLKFYIPDIEKSINSI
VNIIKC

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 37548; Mature: 37548

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFNQDLISVIKNGKLKGKTLKD
CCCEEECEEEEEEECCCCCHHHHHHCCCCCCCCCCCCEEECHHHHHHHHCCCCCCCHHHH
AIELYKNKLMGDCIFDKYKDFPLLLKIISAEKKLSIQVHPGEKDILDLKENPKKEAWYVM
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCEECCCCCCCCCEEEEE
EAKVGSYIILGSKIKDKTVLKQVIDDGTVEDYLYKVPVKKGDIFYIDSGMIHAIGKGVTL
EECCCCEEEECCCCCHHHHHHHHHCCCCHHHEEEECCCCCCCEEEECCCEEEECCCCEEE
IEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPNKKSGLKVQLKNCNKTYCFLSEA
EEEECCCCCEEEEEECCCCCEEEHHHCCCEEEEEECCCCCCCCEEEEECCCCEEEEEHHH
FAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYGEGRQNLSRGDSILIPAYMGDYTLR
HCCEEEEEEEEEECCCCCCEEEEEEEECCCCEEECCCCCCHHCCCCCEEEEEEECCEEEE
GNMNLLKFYIPDIEKSINSIVNIIKC
CCCEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MYPLKFENIYLNKVWGGRGLKKFRDNLPKGDIGESWDIAFNQDLISVIKNGKLKGKTLKD
CCCEEECEEEEEEECCCCCHHHHHHCCCCCCCCCCCCEEECHHHHHHHHCCCCCCCHHHH
AIELYKNKLMGDCIFDKYKDFPLLLKIISAEKKLSIQVHPGEKDILDLKENPKKEAWYVM
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCEECCCCCCCCCEEEEE
EAKVGSYIILGSKIKDKTVLKQVIDDGTVEDYLYKVPVKKGDIFYIDSGMIHAIGKGVTL
EECCCCEEEECCCCCHHHHHHHHHCCCCHHHEEEECCCCCCCEEEECCCEEEECCCCEEE
IEIQQNSDTTYRLYDYNRGRKLDLEKGMNCVNLDIKPNKKSGLKVQLKNCNKTYCFLSEA
EEEECCCCCEEEEEECCCCCEEEHHHCCCEEEEEECCCCCCCCEEEEECCCCEEEEEHHH
FAMEKYEVYYFLKEKSDKERFFIFTCVDGQGQINYGEGRQNLSRGDSILIPAYMGDYTLR
HCCEEEEEEEEEECCCCCCEEEEEEEECCCCEEECCCCCCHHCCCCCEEEEEEECCEEEE
GNMNLLKFYIPDIEKSINSIVNIIKC
CCCEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]