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The map label for this gene is csd [H]

Identifier: 226947593

GI number: 226947593

Start: 455727

End: 457049

Strand: Reverse

Name: csd [H]

Synonym: CLM_0430

Alternate gene names: 226947593

Gene position: 457049-455727 (Counterclockwise)

Preceding gene: 226947606

Following gene: 226947589

Centisome position: 11.0

GC content: 31.59

Gene sequence:

>1323_bases
ATGTATTCTAACAAAAGATCTCCTTATAGATATTTAGTTGTTGGTAGTGACACTAAAGTACCTCTATATAATGGACAACT
AACTCCTTGTATAAATTTTGATAATGCAGCTACTACACCACCTTTAGCTTCTGTAATGAATGCTATTGTCAATTTTTCTC
CTTGGTATTCCTCCATTCACAGAGGCACTGGATATAAATCTCAATTATCTTCTAAAATTTATGAAGATTCTAGGAAAACA
GTTGGCAAGTTTATTGGAGCTGATTTAGATAAAGATGTCATTATATATGTAAAAAATACTACAGAAGCTATTAATAAACT
TTCTTATAGGCTTTGTTCCTGTGATGATGATTCTATAATTTTAACAACCTCTATGGAACATCATTCTAACGATTTACCTT
GGAGAGATAAATATAATGTAGATTATATAGAGGTAGATGACTGTGGAAGATTGGTAATGGAAGATTTAAGAAGCAAATTA
ATAAGGTATGGTGATAAGGTTAAATTAGTTACTATTGCTGGGGCATCTAATGTAACAGGATATATAAACCCTATTTATGA
TATAGCAAAATTAGTTCATGAATTTGGATGCAAAATTTTAGTAGATGGAGCACAACTTGTACCACATTGTAAACTCAGCA
TGAAACCCCATGACAGTTTAGAACACATTGATTATTTAGCTTTTTCTGCGCATAAAATGTATGCACCCTTTGGTATAGGG
GTTTTAATAGGACCTAAAGAAACCTTTGAGAGAGGGAATCCAGATTATAAGGGTGGAGGTACTGTAAATGTAGTAACTAA
AGATTATGTACTATGGACAGATCCTCCTGAAAAAGATGAAGCAGGTACCCCAAACGTTATGGGTGTTATAGCTCTTGCCA
AAGCTATAGATACCATGACAGGCATAGGAATGAAAAATATTGAAATTTATGAACAAGATATTTTCGAATATGCTTTTAGA
AAAATTGCACAAATACCAGATATAAAAATTTATTCTTGCAAAAATCTAGATTACCCTAGAGTTGCTATAATACCTTTTAA
TATAAGTGGTATGCACCATAGCATAACTGCAGAAATACTTTCTAAAGAGTTTGGTATAGCTGTGAGAAATGGCTGTTTTT
GTGCTCAACCGTATGTTCAAAAAATATTAAACATTCCAAAGGAAGAGATAGGGTCATATGCAAATGAGCCTATGAATAAA
AGACCAGGTATGGTTAGATTAAGCTTTGGTATGTATAATGACATTTACGAAATAGACTTTCTAGTTATGGCTCTTAATAA
AATAGTTCAAAACAAAAATAAATATTTAGAAAAATATGGTTAA

Upstream 100 bases:

>100_bases
TCAGTACTCTAAATTCAAATAATCCCATAATATTTTTAAAAATTAAGTTACACTTTTTTATGTTTTTAATACTATATAGT
AGGGGAATAGAGGTGATTAT

Downstream 100 bases:

>100_bases
AATTTAACACCTATAAGTTTGTAGTATTTCCTATAACTTATAGGTGTTAATTTATACCTTTATAATTTAAATTTTTAAAA
CCCTATATTTATAAATAAAT

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MYSNKRSPYRYLVVGSDTKVPLYNGQLTPCINFDNAATTPPLASVMNAIVNFSPWYSSIHRGTGYKSQLSSKIYEDSRKT
VGKFIGADLDKDVIIYVKNTTEAINKLSYRLCSCDDDSIILTTSMEHHSNDLPWRDKYNVDYIEVDDCGRLVMEDLRSKL
IRYGDKVKLVTIAGASNVTGYINPIYDIAKLVHEFGCKILVDGAQLVPHCKLSMKPHDSLEHIDYLAFSAHKMYAPFGIG
VLIGPKETFERGNPDYKGGGTVNVVTKDYVLWTDPPEKDEAGTPNVMGVIALAKAIDTMTGIGMKNIEIYEQDIFEYAFR
KIAQIPDIKIYSCKNLDYPRVAIIPFNISGMHHSITAEILSKEFGIAVRNGCFCAQPYVQKILNIPKEEIGSYANEPMNK
RPGMVRLSFGMYNDIYEIDFLVMALNKIVQNKNKYLEKYG

Sequences:

>Translated_440_residues
MYSNKRSPYRYLVVGSDTKVPLYNGQLTPCINFDNAATTPPLASVMNAIVNFSPWYSSIHRGTGYKSQLSSKIYEDSRKT
VGKFIGADLDKDVIIYVKNTTEAINKLSYRLCSCDDDSIILTTSMEHHSNDLPWRDKYNVDYIEVDDCGRLVMEDLRSKL
IRYGDKVKLVTIAGASNVTGYINPIYDIAKLVHEFGCKILVDGAQLVPHCKLSMKPHDSLEHIDYLAFSAHKMYAPFGIG
VLIGPKETFERGNPDYKGGGTVNVVTKDYVLWTDPPEKDEAGTPNVMGVIALAKAIDTMTGIGMKNIEIYEQDIFEYAFR
KIAQIPDIKIYSCKNLDYPRVAIIPFNISGMHHSITAEILSKEFGIAVRNGCFCAQPYVQKILNIPKEEIGSYANEPMNK
RPGMVRLSFGMYNDIYEIDFLVMALNKIVQNKNKYLEKYG
>Mature_440_residues
MYSNKRSPYRYLVVGSDTKVPLYNGQLTPCINFDNAATTPPLASVMNAIVNFSPWYSSIHRGTGYKSQLSSKIYEDSRKT
VGKFIGADLDKDVIIYVKNTTEAINKLSYRLCSCDDDSIILTTSMEHHSNDLPWRDKYNVDYIEVDDCGRLVMEDLRSKL
IRYGDKVKLVTIAGASNVTGYINPIYDIAKLVHEFGCKILVDGAQLVPHCKLSMKPHDSLEHIDYLAFSAHKMYAPFGIG
VLIGPKETFERGNPDYKGGGTVNVVTKDYVLWTDPPEKDEAGTPNVMGVIALAKAIDTMTGIGMKNIEIYEQDIFEYAFR
KIAQIPDIKIYSCKNLDYPRVAIIPFNISGMHHSITAEILSKEFGIAVRNGCFCAQPYVQKILNIPKEEIGSYANEPMNK
RPGMVRLSFGMYNDIYEIDFLVMALNKIVQNKNKYLEKYG

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=411, Percent_Identity=33.0900243309002, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI1789175, Length=410, Percent_Identity=30.2439024390244, Blast_Score=169, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI193211090, Length=424, Percent_Identity=25.7075471698113, Blast_Score=136, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319831, Length=241, Percent_Identity=26.9709543568465, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 49545; Mature: 49545

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSNKRSPYRYLVVGSDTKVPLYNGQLTPCINFDNAATTPPLASVMNAIVNFSPWYSSIH
CCCCCCCCEEEEEEECCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHH
RGTGYKSQLSSKIYEDSRKTVGKFIGADLDKDVIIYVKNTTEAINKLSYRLCSCDDDSII
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHEECCCCCCEE
LTTSMEHHSNDLPWRDKYNVDYIEVDDCGRLVMEDLRSKLIRYGDKVKLVTIAGASNVTG
EEEEHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
YINPIYDIAKLVHEFGCKILVDGAQLVPHCKLSMKPHDSLEHIDYLAFSAHKMYAPFGIG
CCCHHHHHHHHHHHCCCEEEECCCHHCCCCEECCCCCCCHHHHHHHHHHHHHEECCCCCE
VLIGPKETFERGNPDYKGGGTVNVVTKDYVLWTDPPEKDEAGTPNVMGVIALAKAIDTMT
EEECCHHHHHCCCCCCCCCCEEEEEEECEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
GIGMKNIEIYEQDIFEYAFRKIAQIPDIKIYSCKNLDYPRVAIIPFNISGMHHSITAEIL
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHH
SKEFGIAVRNGCFCAQPYVQKILNIPKEEIGSYANEPMNKRPGMVRLSFGMYNDIYEIDF
HHHCCEEEECCEEECCHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHH
LVMALNKIVQNKNKYLEKYG
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYSNKRSPYRYLVVGSDTKVPLYNGQLTPCINFDNAATTPPLASVMNAIVNFSPWYSSIH
CCCCCCCCEEEEEEECCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHH
RGTGYKSQLSSKIYEDSRKTVGKFIGADLDKDVIIYVKNTTEAINKLSYRLCSCDDDSII
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHEECCCCCCEE
LTTSMEHHSNDLPWRDKYNVDYIEVDDCGRLVMEDLRSKLIRYGDKVKLVTIAGASNVTG
EEEEHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
YINPIYDIAKLVHEFGCKILVDGAQLVPHCKLSMKPHDSLEHIDYLAFSAHKMYAPFGIG
CCCHHHHHHHHHHHCCCEEEECCCHHCCCCEECCCCCCCHHHHHHHHHHHHHEECCCCCE
VLIGPKETFERGNPDYKGGGTVNVVTKDYVLWTDPPEKDEAGTPNVMGVIALAKAIDTMT
EEECCHHHHHCCCCCCCCCCEEEEEEECEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
GIGMKNIEIYEQDIFEYAFRKIAQIPDIKIYSCKNLDYPRVAIIPFNISGMHHSITAEIL
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHH
SKEFGIAVRNGCFCAQPYVQKILNIPKEEIGSYANEPMNKRPGMVRLSFGMYNDIYEIDF
HHHCCEEEECCEEECCHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHH
LVMALNKIVQNKNKYLEKYG
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA