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The map label for this gene is ykvY [H]

Identifier: 226947575

GI number: 226947575

Start: 433051

End: 434133

Strand: Direct

Name: ykvY [H]

Synonym: CLM_0412

Alternate gene names: 226947575

Gene position: 433051-434133 (Clockwise)

Preceding gene: 226947574

Following gene: 226947576

Centisome position: 10.42

GC content: 30.29

Gene sequence:

>1083_bases
ATGAACCAAGAAAGACTTAATAAAGTTTTAGAGGGAATGAAAGAAAGAGAAATTCCTCAAATGTTGATTTCAGATGCACC
AGCTATATTTTATTTAACAGGAAAATGGATTCATACAGGAGAAAGATTAATAGCTCTTTACCTTAATGAAAATGGAAACC
ATAAATTATTTATAAATGAATTATTCCCAGTAACTGAAGACTTAGGAGTAGAAAAAGTTTGGTTTAATGATAACCAAGAT
GGAGTAGAAATAATTTCTAAATATGTTGAAAAAGATAAAGTAATGGGTGTAGATAAAAATTGGCCAGCACGTTTTTTATT
AAGACTTATGGAATTACAAGGCGGAAGCAAATTTGTTAATGGTTCAATAATAATAGATAGAGCAAGAATGTTCAAAGATG
AAAAAGAAAAAGAATTAATGAGAGCTTCATCAAAAGCAAATGACGCTGCTATGGAAAAATTATATAACTTATTTAAAGAA
AATCAAGATTTATCAGAAAAAGAAGTTGGTGAAAGACTTGCAAAAATTTATAGTGACTTAGGTGCAGAAAGATTCTCATT
TGATCCAATAGTAGGATATGGAGCAAATGCAGCAGATCCACATCATGAAAATGATGGTTCTAAACTTAAAGAAGGAGATT
GCATAGTTTTAGATATAGGTTGTGTAAAAGATTCTTATTGTTCAGATATGACTAGAGTTTTCTTCTATAAAAGTGTTCCA
GAACATTCAAAAAAAGTTTATGATACAGTAGTAGCTGCTAATATGGCAGGTATAGCTGCTGTTAAACCAGGAGTAAGATT
CTGTGATATAGATAAAGCTTCTAGAGATGTTATAGAAAAAGCTGGATATGGAAAATACTTTACTCATAGAACAGGACATT
CAATTGGTATAGAAGATCACGATTTAGGAGACGTTTCAGCAGTTAACACTGAAGAAATAAAACCAGGAATGATATTCTCA
ATAGAACCAGGTATATACTTACCAGGTGAAGTTGGTGTTAGAATAGAAGACTTAGTTTTAGTAACAGAAGACGGTTGTGA
AGTTTTAAATAAATATAGTAAAGAGTTAACTATAATAGAATAA

Upstream 100 bases:

>100_bases
TATCTAAAGGATAGTCTCTTTCACAAATAAATATTGATTTTGTTTCTCTTTTATTATATAGAGAATAAAAAAATAAATAT
AATTATAGGAGTGGATTTTT

Downstream 100 bases:

>100_bases
ATTTTTTATATAAGTATCCTATAAACAGTACCCTTTAGTAATAAAAATAACTATGTAAAAAGTATATTATAAAATATATT
TTTTCATAGTTATTTTTTTA

Product: metallopeptidase, family M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MNQERLNKVLEGMKEREIPQMLISDAPAIFYLTGKWIHTGERLIALYLNENGNHKLFINELFPVTEDLGVEKVWFNDNQD
GVEIISKYVEKDKVMGVDKNWPARFLLRLMELQGGSKFVNGSIIIDRARMFKDEKEKELMRASSKANDAAMEKLYNLFKE
NQDLSEKEVGERLAKIYSDLGAERFSFDPIVGYGANAADPHHENDGSKLKEGDCIVLDIGCVKDSYCSDMTRVFFYKSVP
EHSKKVYDTVVAANMAGIAAVKPGVRFCDIDKASRDVIEKAGYGKYFTHRTGHSIGIEDHDLGDVSAVNTEEIKPGMIFS
IEPGIYLPGEVGVRIEDLVLVTEDGCEVLNKYSKELTIIE

Sequences:

>Translated_360_residues
MNQERLNKVLEGMKEREIPQMLISDAPAIFYLTGKWIHTGERLIALYLNENGNHKLFINELFPVTEDLGVEKVWFNDNQD
GVEIISKYVEKDKVMGVDKNWPARFLLRLMELQGGSKFVNGSIIIDRARMFKDEKEKELMRASSKANDAAMEKLYNLFKE
NQDLSEKEVGERLAKIYSDLGAERFSFDPIVGYGANAADPHHENDGSKLKEGDCIVLDIGCVKDSYCSDMTRVFFYKSVP
EHSKKVYDTVVAANMAGIAAVKPGVRFCDIDKASRDVIEKAGYGKYFTHRTGHSIGIEDHDLGDVSAVNTEEIKPGMIFS
IEPGIYLPGEVGVRIEDLVLVTEDGCEVLNKYSKELTIIE
>Mature_360_residues
MNQERLNKVLEGMKEREIPQMLISDAPAIFYLTGKWIHTGERLIALYLNENGNHKLFINELFPVTEDLGVEKVWFNDNQD
GVEIISKYVEKDKVMGVDKNWPARFLLRLMELQGGSKFVNGSIIIDRARMFKDEKEKELMRASSKANDAAMEKLYNLFKE
NQDLSEKEVGERLAKIYSDLGAERFSFDPIVGYGANAADPHHENDGSKLKEGDCIVLDIGCVKDSYCSDMTRVFFYKSVP
EHSKKVYDTVVAANMAGIAAVKPGVRFCDIDKASRDVIEKAGYGKYFTHRTGHSIGIEDHDLGDVSAVNTEEIKPGMIFS
IEPGIYLPGEVGVRIEDLVLVTEDGCEVLNKYSKELTIIE

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=268, Percent_Identity=26.1194029850746, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI149589008, Length=322, Percent_Identity=26.7080745341615, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI260593665, Length=323, Percent_Identity=27.2445820433437, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI260593663, Length=267, Percent_Identity=26.5917602996255, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1788728, Length=238, Percent_Identity=40.3361344537815, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789275, Length=267, Percent_Identity=22.8464419475655, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17508215, Length=299, Percent_Identity=28.0936454849498, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17509539, Length=231, Percent_Identity=27.7056277056277, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507601, Length=256, Percent_Identity=28.125, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320922, Length=245, Percent_Identity=23.265306122449, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19920384, Length=285, Percent_Identity=25.2631578947368, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40551; Mature: 40551

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQERLNKVLEGMKEREIPQMLISDAPAIFYLTGKWIHTGERLIALYLNENGNHKLFINE
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEECCCEEEEEEEECCCCEEEEECC
LFPVTEDLGVEKVWFNDNQDGVEIISKYVEKDKVMGVDKNWPARFLLRLMELQGGSKFVN
CCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCEEEC
GSIIIDRARMFKDEKEKELMRASSKANDAAMEKLYNLFKENQDLSEKEVGERLAKIYSDL
CCEEEEHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GAERFSFDPIVGYGANAADPHHENDGSKLKEGDCIVLDIGCVKDSYCSDMTRVFFYKSVP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
EHSKKVYDTVVAANMAGIAAVKPGVRFCDIDKASRDVIEKAGYGKYFTHRTGHSIGIEDH
HHHHHHHHHHHHHHHCCHHEECCCCEEECCCHHHHHHHHHCCCCCCEECCCCCCCCCCCC
DLGDVSAVNTEEIKPGMIFSIEPGIYLPGEVGVRIEDLVLVTEDGCEVLNKYSKELTIIE
CCCCCCCCCHHHCCCCEEEEECCCEECCCCCCCEEEEEEEEECCHHHHHHHHCCCEEEEC
>Mature Secondary Structure
MNQERLNKVLEGMKEREIPQMLISDAPAIFYLTGKWIHTGERLIALYLNENGNHKLFINE
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEECCCEEEEEEEECCCCEEEEECC
LFPVTEDLGVEKVWFNDNQDGVEIISKYVEKDKVMGVDKNWPARFLLRLMELQGGSKFVN
CCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCEEEC
GSIIIDRARMFKDEKEKELMRASSKANDAAMEKLYNLFKENQDLSEKEVGERLAKIYSDL
CCEEEEHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GAERFSFDPIVGYGANAADPHHENDGSKLKEGDCIVLDIGCVKDSYCSDMTRVFFYKSVP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
EHSKKVYDTVVAANMAGIAAVKPGVRFCDIDKASRDVIEKAGYGKYFTHRTGHSIGIEDH
HHHHHHHHHHHHHHHCCHHEECCCCEEECCCHHHHHHHHHCCCCCCEECCCCCCCCCCCC
DLGDVSAVNTEEIKPGMIFSIEPGIYLPGEVGVRIEDLVLVTEDGCEVLNKYSKELTIIE
CCCCCCCCCHHHCCCCEEEEECCCEECCCCCCCEEEEEEEEECCHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]