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The map label for this gene is yxdK [H]

Identifier: 226947550

GI number: 226947550

Start: 407960

End: 408940

Strand: Direct

Name: yxdK [H]

Synonym: CLM_0387

Alternate gene names: 226947550

Gene position: 407960-408940 (Clockwise)

Preceding gene: 226947549

Following gene: 226947551

Centisome position: 9.82

GC content: 26.71

Gene sequence:

>981_bases
ATGAAGTTATTTATAAAAGACAATAAAGGATATATAGTTGTATATTTTATAAGTATTTTTATTACATTGGGATACTTAGC
TCTTTCAGGATTTGTACAAATTGGTGAGTACTTATATATAGTATTATTTAATACATTTATTTTAGGATGCTTTTTATTTT
TTAGATATTATAAGAGTAAAGAGGTATATAGATTTTTAGATGAGGGTCTAAATAATTTAGATGAATCTTTTTTAGATTTA
GGAAATTCAGTTTTAGGGGAAGGTATCTCTAATATTTTAAAGAAAGAGCATAATTTATATGAAGCTGAAACTATAAAACA
CAATAAGGCTTATAATGATCATCTAACATTTATAAATCAATGGGTTCATCAGATGAAAACACCTCTATCAGTAATTCAAC
TACAAATGCAAGAATACGAGGGAGAAGAACCTTTTGATAGTATGAAGGTGGAGATAAGTAAATTAAATAGAGGATTAAAT
ATGGCTATGTATTTTGCTAGACTTGATTCTTTTCAAAAAGATTTCATAGTAGAAAAATTTTCTTTATATAATTTAGTTAT
GAGTAAAGTTAATGAAGAAAAGCAGATATTTATTAAAAATAGGATATTACCAAAAGTTGAAATAGATGATTCTATAGAAG
TATACAGCGATGTTAAATGGATGAAATTTGTATTAGAACAGCTCATTGTTAATGGAGTAAAATATTCCAAAGATAAGGGG
AAAGAACTGATTATAAGAGCTTATGATGAGGAAAATGCTGTTAAGTTAAGTGTAATTGATAAAGGTGTAGGAATACCAAA
AAAAGATATTAAAAGAGTTTTCGATCCATTTTTTACAGGGGAAAATGGACGTAATTTTGGAGAATCTACTGGAATGGGAT
TACATATAGTTAAAAGGATTTGTGACAGTTTAGGGCATAATGTATTTATAGAGTCTAAGGTTTCAGAGGGAACAACTGTT
TCCATAATATTTAAAAAGTAG

Upstream 100 bases:

>100_bases
AATAAGAAAAAGACTTCATGAGTTAGGAATAGAAGACGGAATAGAAACCGTAAGAGGTGTGGGATATAGATTGAATAAAA
CTTGGTAGGGAGCAGAAAAA

Downstream 100 bases:

>100_bases
GGTATCATATTTAATATATAAATAGGATAGATAGTTTAAAACTATACTATTCTATTTTTTTATTAATTAATAAGTGTGAC
ATACATGTCATACTTATGTA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKLFIKDNKGYIVVYFISIFITLGYLALSGFVQIGEYLYIVLFNTFILGCFLFFRYYKSKEVYRFLDEGLNNLDESFLDL
GNSVLGEGISNILKKEHNLYEAETIKHNKAYNDHLTFINQWVHQMKTPLSVIQLQMQEYEGEEPFDSMKVEISKLNRGLN
MAMYFARLDSFQKDFIVEKFSLYNLVMSKVNEEKQIFIKNRILPKVEIDDSIEVYSDVKWMKFVLEQLIVNGVKYSKDKG
KELIIRAYDEENAVKLSVIDKGVGIPKKDIKRVFDPFFTGENGRNFGESTGMGLHIVKRICDSLGHNVFIESKVSEGTTV
SIIFKK

Sequences:

>Translated_326_residues
MKLFIKDNKGYIVVYFISIFITLGYLALSGFVQIGEYLYIVLFNTFILGCFLFFRYYKSKEVYRFLDEGLNNLDESFLDL
GNSVLGEGISNILKKEHNLYEAETIKHNKAYNDHLTFINQWVHQMKTPLSVIQLQMQEYEGEEPFDSMKVEISKLNRGLN
MAMYFARLDSFQKDFIVEKFSLYNLVMSKVNEEKQIFIKNRILPKVEIDDSIEVYSDVKWMKFVLEQLIVNGVKYSKDKG
KELIIRAYDEENAVKLSVIDKGVGIPKKDIKRVFDPFFTGENGRNFGESTGMGLHIVKRICDSLGHNVFIESKVSEGTTV
SIIFKK
>Mature_326_residues
MKLFIKDNKGYIVVYFISIFITLGYLALSGFVQIGEYLYIVLFNTFILGCFLFFRYYKSKEVYRFLDEGLNNLDESFLDL
GNSVLGEGISNILKKEHNLYEAETIKHNKAYNDHLTFINQWVHQMKTPLSVIQLQMQEYEGEEPFDSMKVEISKLNRGLN
MAMYFARLDSFQKDFIVEKFSLYNLVMSKVNEEKQIFIKNRILPKVEIDDSIEVYSDVKWMKFVLEQLIVNGVKYSKDKG
KELIIRAYDEENAVKLSVIDKGVGIPKKDIKRVFDPFFTGENGRNFGESTGMGLHIVKRICDSLGHNVFIESKVSEGTTV
SIIFKK

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=213, Percent_Identity=23.4741784037559, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=24.7826086956522, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37845; Mature: 37845

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFIKDNKGYIVVYFISIFITLGYLALSGFVQIGEYLYIVLFNTFILGCFLFFRYYKSK
CEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVYRFLDEGLNNLDESFLDLGNSVLGEGISNILKKEHNLYEAETIKHNKAYNDHLTFINQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHH
WVHQMKTPLSVIQLQMQEYEGEEPFDSMKVEISKLNRGLNMAMYFARLDSFQKDFIVEKF
HHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
SLYNLVMSKVNEEKQIFIKNRILPKVEIDDSIEVYSDVKWMKFVLEQLIVNGVKYSKDKG
HHHHHHHHHCCCHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KELIIRAYDEENAVKLSVIDKGVGIPKKDIKRVFDPFFTGENGRNFGESTGMGLHIVKRI
CEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
CDSLGHNVFIESKVSEGTTVSIIFKK
HHHCCCCEEEEEECCCCCEEEEEEEC
>Mature Secondary Structure
MKLFIKDNKGYIVVYFISIFITLGYLALSGFVQIGEYLYIVLFNTFILGCFLFFRYYKSK
CEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVYRFLDEGLNNLDESFLDLGNSVLGEGISNILKKEHNLYEAETIKHNKAYNDHLTFINQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHH
WVHQMKTPLSVIQLQMQEYEGEEPFDSMKVEISKLNRGLNMAMYFARLDSFQKDFIVEKF
HHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
SLYNLVMSKVNEEKQIFIKNRILPKVEIDDSIEVYSDVKWMKFVLEQLIVNGVKYSKDKG
HHHHHHHHHCCCHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KELIIRAYDEENAVKLSVIDKGVGIPKKDIKRVFDPFFTGENGRNFGESTGMGLHIVKRI
CEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
CDSLGHNVFIESKVSEGTTVSIIFKK
HHHCCCCEEEEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]