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The map label for this gene is murA [H]

Identifier: 226947383

GI number: 226947383

Start: 187525

End: 188781

Strand: Direct

Name: murA [H]

Synonym: CLM_0203

Alternate gene names: 226947383

Gene position: 187525-188781 (Clockwise)

Preceding gene: 226947382

Following gene: 226947384

Centisome position: 4.51

GC content: 33.25

Gene sequence:

>1257_bases
ATGGATAAGATAGTGGTTAATGGTGGAAGTCAATTAAAAGGTGATGTAAACATAAGTACAGCTAAAAATTCAGTATTACC
AATCATTGCAGGTAGTATATTGAGTGGAAATAAATGCGTTATAGATAATGCACCAATGCTAGAGGATGTATTTGTTATTG
GAGAAATTTTAAAAAGTATTTCAGCCAAAGTTAATATAGATGAGGTTAATAACAGGGTTATAATAGATTCTGAACCAGTG
GATAATTTAGAACCTGATAGTGATTTAGTTAAAAAAATGAGAGCATCATTTTTGCTAATGGGACCTATGATGTCTAGGTT
TGGAAGGTTTAAGATATCATTACCAGGAGGATGTAATATAGGTACAAGACCCATAGATTTACATTTAAAAGGATTCACTG
CCCTTGGAGCAAAAGTTAACATAGGGCATGGTTATGTAGAAGCTGTAGCAGATAAATTGATAGGAAATAAAATTTATTTA
GATTTTCCTTCTGTAGGGGCTACGGAAAATATAATGATGGCATCAGTTATGGCAGAAGGAGAGACCATTATAGAAAATGC
AGCAGAAGAACCAGAAATAGAGGATTTAGGAAGGTTTTTAAACAGCATAGGAGCAAATATTATAGGAGCAGGGACAGATA
CAGTAAGAATAATAGGTGTTAATGAATTAAATGGAACAACACATAGACCTATATATGATAGAATAGAAGCAGGAACTTTT
ATGATAGCTGCTGCCATAACTAAGAGTAGAATAAAAATAAATGGTGTTATAGAAGAACATTTAAAGCCTATAATCGCAAA
GCTTACAGAGATGGGTGTTGATATAAAAATAAAAGGAGAAACTGCTACAGTAGATGGAAGAAAAGTATTAAATCCAGTAG
ATATAAAAACTATGCCCTATCCGGGTTTCCCAACGGATATGCAGGCTCAAATGATGGCTTTATTGGCCACTATAAAAGGA
ACCAGTATTATTACAGAAACTATATTTGAAAATAGATTTATGCATGTATCTGAAATGAAGAGAATGGGTGCAGATGTAAA
AATAGATGGAAGAAGTGCCGTAATAGAAGGTGTAAGTAAATTAACAGGAACAGAAGTTAAAGCTACAGATCTAAGGGCAG
GAGCGGCTCTTATATTATGCGCTCTAGCAGCTGAAGGCAAAACAGAAATAACAGATGTATATCATATAGATAGAGGATAT
GTAAAAATAGAGGAAAAGTTAAATAAATTAGGAGCAAATATTAGACGAGTACATTAA

Upstream 100 bases:

>100_bases
ATTATGCTGTATGTAAATATAATTCAGAAAAAACTTACTTAATATTGGGAACGCCACAGATAAACCTAACATATTAGTAA
TATCGAAATGGAGGATAATA

Downstream 100 bases:

>100_bases
AATTTAATAATTGTGTATGATAAATAACTCATGGTGATTATTTGCTATGAGTTTTTATTATATATATAAACTTTTGAGTT
TATATACTAAGCTTATTTAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MDKIVVNGGSQLKGDVNISTAKNSVLPIIAGSILSGNKCVIDNAPMLEDVFVIGEILKSISAKVNIDEVNNRVIIDSEPV
DNLEPDSDLVKKMRASFLLMGPMMSRFGRFKISLPGGCNIGTRPIDLHLKGFTALGAKVNIGHGYVEAVADKLIGNKIYL
DFPSVGATENIMMASVMAEGETIIENAAEEPEIEDLGRFLNSIGANIIGAGTDTVRIIGVNELNGTTHRPIYDRIEAGTF
MIAAAITKSRIKINGVIEEHLKPIIAKLTEMGVDIKIKGETATVDGRKVLNPVDIKTMPYPGFPTDMQAQMMALLATIKG
TSIITETIFENRFMHVSEMKRMGADVKIDGRSAVIEGVSKLTGTEVKATDLRAGAALILCALAAEGKTEITDVYHIDRGY
VKIEEKLNKLGANIRRVH

Sequences:

>Translated_418_residues
MDKIVVNGGSQLKGDVNISTAKNSVLPIIAGSILSGNKCVIDNAPMLEDVFVIGEILKSISAKVNIDEVNNRVIIDSEPV
DNLEPDSDLVKKMRASFLLMGPMMSRFGRFKISLPGGCNIGTRPIDLHLKGFTALGAKVNIGHGYVEAVADKLIGNKIYL
DFPSVGATENIMMASVMAEGETIIENAAEEPEIEDLGRFLNSIGANIIGAGTDTVRIIGVNELNGTTHRPIYDRIEAGTF
MIAAAITKSRIKINGVIEEHLKPIIAKLTEMGVDIKIKGETATVDGRKVLNPVDIKTMPYPGFPTDMQAQMMALLATIKG
TSIITETIFENRFMHVSEMKRMGADVKIDGRSAVIEGVSKLTGTEVKATDLRAGAALILCALAAEGKTEITDVYHIDRGY
VKIEEKLNKLGANIRRVH
>Mature_418_residues
MDKIVVNGGSQLKGDVNISTAKNSVLPIIAGSILSGNKCVIDNAPMLEDVFVIGEILKSISAKVNIDEVNNRVIIDSEPV
DNLEPDSDLVKKMRASFLLMGPMMSRFGRFKISLPGGCNIGTRPIDLHLKGFTALGAKVNIGHGYVEAVADKLIGNKIYL
DFPSVGATENIMMASVMAEGETIIENAAEEPEIEDLGRFLNSIGANIIGAGTDTVRIIGVNELNGTTHRPIYDRIEAGTF
MIAAAITKSRIKINGVIEEHLKPIIAKLTEMGVDIKIKGETATVDGRKVLNPVDIKTMPYPGFPTDMQAQMMALLATIKG
TSIITETIFENRFMHVSEMKRMGADVKIDGRSAVIEGVSKLTGTEVKATDLRAGAALILCALAAEGKTEITDVYHIDRGY
VKIEEKLNKLGANIRRVH

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=47.9713603818616, Blast_Score=377, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45083; Mature: 45083

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVVNGGSQLKGDVNISTAKNSVLPIIAGSILSGNKCVIDNAPMLEDVFVIGEILKSI
CCEEEECCCCCEECCEEEECCCCCEEEEEECCEECCCEEEECCCCHHHHHHHHHHHHHHH
SAKVNIDEVNNRVIIDSEPVDNLEPDSDLVKKMRASFLLMGPMMSRFGRFKISLPGGCNI
CCEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
GTRPIDLHLKGFTALGAKVNIGHGYVEAVADKLIGNKIYLDFPSVGATENIMMASVMAEG
CCCEEEEEEECEEEECCEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCC
ETIIENAAEEPEIEDLGRFLNSIGANIIGAGTDTVRIIGVNELNGTTHRPIYDRIEAGTF
HHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEEEECCCCCCCCCHHHHHCCCCE
MIAAAITKSRIKINGVIEEHLKPIIAKLTEMGVDIKIKGETATVDGRKVLNPVDIKTMPY
EEEEEHHHCEEEEECHHHHHHHHHHHHHHHCCCEEEECCCEEEECCHHCCCCCCCEECCC
PGFPTDMQAQMMALLATIKGTSIITETIFENRFMHVSEMKRMGADVKIDGRSAVIEGVSK
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHCCCCEEECCHHHHHHHHHH
LTGTEVKATDLRAGAALILCALAAEGKTEITDVYHIDRGYVKIEEKLNKLGANIRRVH
HCCCCEEEHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCEEEHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDKIVVNGGSQLKGDVNISTAKNSVLPIIAGSILSGNKCVIDNAPMLEDVFVIGEILKSI
CCEEEECCCCCEECCEEEECCCCCEEEEEECCEECCCEEEECCCCHHHHHHHHHHHHHHH
SAKVNIDEVNNRVIIDSEPVDNLEPDSDLVKKMRASFLLMGPMMSRFGRFKISLPGGCNI
CCEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
GTRPIDLHLKGFTALGAKVNIGHGYVEAVADKLIGNKIYLDFPSVGATENIMMASVMAEG
CCCEEEEEEECEEEECCEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCC
ETIIENAAEEPEIEDLGRFLNSIGANIIGAGTDTVRIIGVNELNGTTHRPIYDRIEAGTF
HHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEEEECCCCCCCCCHHHHHCCCCE
MIAAAITKSRIKINGVIEEHLKPIIAKLTEMGVDIKIKGETATVDGRKVLNPVDIKTMPY
EEEEEHHHCEEEEECHHHHHHHHHHHHHHHCCCEEEECCCEEEECCHHCCCCCCCEECCC
PGFPTDMQAQMMALLATIKGTSIITETIFENRFMHVSEMKRMGADVKIDGRSAVIEGVSK
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHCCCCEEECCHHHHHHHHHH
LTGTEVKATDLRAGAALILCALAAEGKTEITDVYHIDRGYVKIEEKLNKLGANIRRVH
HCCCCEEEHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCEEEHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]