Click here to switch to the map view.

The map label for this gene is ipk [H]

Identifier: 226947344

GI number: 226947344

Start: 152310

End: 153152

Strand: Direct

Name: ipk [H]

Synonym: CLM_0164

Alternate gene names: 226947344

Gene position: 152310-153152 (Clockwise)

Preceding gene: 226947343

Following gene: 226947345

Centisome position: 3.67

GC content: 27.64

Gene sequence:

>843_bases
ATGTTATCAAAAGCTCATGCTAAAGTAAATTTATCCTTAGACGTAATAGGAAAAAGAAAAGATGGATATCATCTTTTAAA
GATGTTAATGCAGACCATAGATTTATATGATTTAATAGAAATAAAAAAAATAAAAAAAGGTATAATAATAGATTGTGATA
GAGAGTATATACCTAAAGATAGGAGAAATTTGGCATATAAAGCAGCAGAACTATTTTTAGATAGATACAATATAGATTCT
GGAGTTAGAATAGATATAACTAAAAATATACCAGTAGCAGCAGGATTAGCAGGGGGAAGCACAGATGCAGCTACAGTCTT
GAAAATAATGAGGGATATATTTAGACCAGACATAAGTAATGAAGAATTAAAAGAGATAGCTTTAGATATTGGGGCAGATG
TGCCGTTTTGTATAGAAGGTGGGACAGCTCTTTGTGAAGGTATAGGAGAGAAAATTACTCCTATAAAAAATTTTAAGAAT
CAAATATTAGTATTAGTTAAGCCTAATTTTGGGTTATCTACAAAAGATGTATACAATAATTTAAAAGTAGAAAAAATATA
TATTCATCCTAATACAACAAAATTAATACAATCAATAGAAGAAGATAATTTGAAATCTGTAGCTAGAAATATGAGGAATG
TCTTAGAAAATGTTACATTAAGAAAATATAAGGCATTAAATTCTATAAAAAGTAATTTTATAGAGTTAGGAGCATTAGGA
AGTATGATGAGTGGTAGCGGACCAAGTGTATTTGGATTATTTGATGATATGCTAAAGGCTCAAATATGTTATGATAATAT
GAAAGAGAAGTATAAAGAAGTATTTATAACAAGAACAATATAA

Upstream 100 bases:

>100_bases
TAGCATAGGATTAAAGCTACAATTTATGAATATCATGATTGTAGCTTTAATTTTTTTGATGTATTATATATTCTATAATA
TATATTTTTGGAGGAATAAA

Downstream 100 bases:

>100_bases
TAGTTGAAAGACCATAGAAATATATTTTAAGAATTATTTATATGGTCTTTTTTTTTTATTATCTTACTAGTTGTACATAA
AGCTAAAGTTTTTACCTAAA

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MLSKAHAKVNLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKGIIIDCDREYIPKDRRNLAYKAAELFLDRYNIDS
GVRIDITKNIPVAAGLAGGSTDAATVLKIMRDIFRPDISNEELKEIALDIGADVPFCIEGGTALCEGIGEKITPIKNFKN
QILVLVKPNFGLSTKDVYNNLKVEKIYIHPNTTKLIQSIEEDNLKSVARNMRNVLENVTLRKYKALNSIKSNFIELGALG
SMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI

Sequences:

>Translated_280_residues
MLSKAHAKVNLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKGIIIDCDREYIPKDRRNLAYKAAELFLDRYNIDS
GVRIDITKNIPVAAGLAGGSTDAATVLKIMRDIFRPDISNEELKEIALDIGADVPFCIEGGTALCEGIGEKITPIKNFKN
QILVLVKPNFGLSTKDVYNNLKVEKIYIHPNTTKLIQSIEEDNLKSVARNMRNVLENVTLRKYKALNSIKSNFIELGALG
SMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI
>Mature_280_residues
MLSKAHAKVNLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKGIIIDCDREYIPKDRRNLAYKAAELFLDRYNIDS
GVRIDITKNIPVAAGLAGGSTDAATVLKIMRDIFRPDISNEELKEIALDIGADVPFCIEGGTALCEGIGEKITPIKNFKN
QILVLVKPNFGLSTKDVYNNLKVEKIYIHPNTTKLIQSIEEDNLKSVARNMRNVLENVTLRKYKALNSIKSNFIELGALG
SMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=273, Percent_Identity=31.1355311355311, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 31467; Mature: 31467

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKAHAKVNLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKGIIIDCDREYIPKD
CCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHCCCH
RRNLAYKAAELFLDRYNIDSGVRIDITKNIPVAAGLAGGSTDAATVLKIMRDIFRPDISN
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCH
EELKEIALDIGADVPFCIEGGTALCEGIGEKITPIKNFKNQILVLVKPNFGLSTKDVYNN
HHHHHHHHHHCCCCCEEECCCHHHHHHCCCCCCHHHCCCCCEEEEECCCCCCCHHHHHCC
LKVEKIYIHPNTTKLIQSIEEDNLKSVARNMRNVLENVTLRKYKALNSIKSNFIELGALG
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MLSKAHAKVNLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKGIIIDCDREYIPKD
CCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHCCCH
RRNLAYKAAELFLDRYNIDSGVRIDITKNIPVAAGLAGGSTDAATVLKIMRDIFRPDISN
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCH
EELKEIALDIGADVPFCIEGGTALCEGIGEKITPIKNFKNQILVLVKPNFGLSTKDVYNN
HHHHHHHHHHCCCCCEEECCCHHHHHHCCCCCCHHHCCCCCEEEEECCCCCCCHHHHHCC
LKVEKIYIHPNTTKLIQSIEEDNLKSVARNMRNVLENVTLRKYKALNSIKSNFIELGALG
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA