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The map label for this gene is nrdD [H]

Identifier: 226947317

GI number: 226947317

Start: 116913

End: 119054

Strand: Direct

Name: nrdD [H]

Synonym: CLM_0137

Alternate gene names: 226947317

Gene position: 116913-119054 (Clockwise)

Preceding gene: 226947316

Following gene: 226947318

Centisome position: 2.81

GC content: 29.65

Gene sequence:

>2142_bases
ATGCTATATGTTGTGAAAAGAGACGGTAGAAAAGTAGAAATTGATGTTGTTAAAATATCAAATGCTATTAAAGGTGCAGC
AGAAGAAATTGCTTTTGATATGAAGGAAAGTGAAAATATAAGTCTAACTCAAAAGGTTATAAAAAAGATAGAAGATTCTA
ATAAAGAGGAAATATCAGTAGAAGATATACAAAATTTAGTTGAGCATGTTTTAATTGATAGCGGATTTAAAGAAATAGGG
TATGCCTATTCAAATTATAGAAGAGAGAGAACAAAAATAAGAGAAATAAAATCTGAATTGATGACAGCTATAGAAAAAAT
AGGGGTAGAAACAGATAGAGATAACGCGAATGTAGGTAATAATTTCAGCTCTAAATTATTAAGAATAGCTAGTGAATCTA
ACAAATGGTATAATTTAGGGGTTATGCCAAAGCATTTAGCTAAATTACATGAAAATGGAGATATATATTATCATGATTTA
GATAGTTACAATTTAACAGTAAATTGTTTAAATATAGATACAGGGCGAATATTACAAAGAGGATTCAATACGGGTTACGG
TACAATTAATGCTCCAAAGAGAATTGAAAGTGCTGCAGAGTTAAGTTGTATATTACTTCAATCTACTCAAAATGATATGT
TTGGAGGTCAAGCACACGTAAATTTTGATAATGATATGGCTTTATTTATTCCTAATACTAGATCTGAAATAAGAAAAGAA
ATATTAGAAAATTTAAAGGGATTAGAGGTACAAGAAGAAGTTTTAAATAAAGAAAAAATTGATGAATTAGTAGAAGAACG
ATTAAGACTACGCATACATCAAGCTATGCAAGGAATAGTCTATAATTTAAATACTATGCATTCTAGAGCAGGATCACAAG
TACCTTTTAGTTCTATAAATATAGGAATACCTAAAAATAAAGATGCGGCTTTAATATGTGAAATATTTTTAAAAGAGTAT
GAAAAAGGATTAGGAAAAGGTGAACAGCCAATATTCCCTAATATAATATTTAGAGTAAAAGAGGGAGTAAATAGAGAAGA
GAAGGATCCTTACTACTATTTATTTAAATTAGCTGCTAAAATAGCAGGTAAGAGAATGAACCCTACTTTTATGAATATGG
ATTCAGACTTTAACAAAGAATATTATGATAAAGGAATAATACCAGCTACTATGGGATGCAGAACTTATGTATGTTCAAAT
ATAAGTGGTGAAGAAGGACCAGCCGGTAGAGGAAATATAGCTCCAACTACTATAAACCTTCCTAGGGTTGGAATATTAGC
TAAAAAGGATATAAATAAATTTTTTAATTTACTAGATAATAGATTAGAACTAGCAAGAGAATCTTTATTGCATAGATATA
ATGTACTAAAAAAATTAAGAGTTAAAGATTTACCTTTTGTTGTAGGAGAAGGCCTTATGAAGGGTTCAGAAAATTTATTA
CCGGATGATTCTATTGAGCCTATTTTAAAACAAGGGTCTTGGGCTATAGGGTTCATAGGTATAGCAGAAACTTTGACAGC
CCTTATAGGAAGTCATCACGGGGAAACAGAAGAGGCTAAAGAATTAGGGGTAAAAATAGTTTCTCATATAAGAGATTTCT
GTGACAAATATAAAGAAATAGATAAATTAAATTGGAGTTGCTATGCCACACCTGCAGAGGGATTAAGTGGTAAGTTTATT
CTTCAAGATAAAAAAGTTTTTGGAGAAATAAAAGGTGTTACAGATAAGAACTACTATACTAATAGTTATCATATACCAGT
AGGTTTTCCAATATCAATTAAGGAAAAGATAAATATAGAGGCTCCTTATCATAAAATATGTAATGGCGGACATATAAGTT
ATATCGAGTTAGATGATTATCCATCAGAAGAGGTAATTATGGATATAATCCAATATGCATATAGAAATACTAACATATCT
TATATGGGGATAAATTTCCATATAAAATATTGTAGAGAATGTGGAACATATCTTGGAGTAGAGGAAGAAGCTTGTAATAA
TTGTGGAAGTACAAATATACAAGGAATATCTAGAGTAACAGGATATTTAAGCTTAGATGAGAGATTTGGTTCTGGTAAAG
TAGCAGAAAGAGCTGATAGGACATCAAATAATTCTAGTCATAGAAAAATTTATAATGCATAA

Upstream 100 bases:

>100_bases
CGGTATATTTATTTAAATATAAAATTGCTGAAAAAAATTTAAGATAGTATAATGTTCAAAGTACATATACACAATATGTT
GTAGGTAGGAGGAATATAGT

Downstream 100 bases:

>100_bases
ATTGAGGTGTTTGGCTATGGAGAATAAATATTTACAAGTAGCAGGCTTTTTAGATAATTCCTTAGTTAATGGATTAGGAC
TAAGGTCAGTAGTATTTGTA

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 713

Protein sequence:

>713_residues
MLYVVKRDGRKVEIDVVKISNAIKGAAEEIAFDMKESENISLTQKVIKKIEDSNKEEISVEDIQNLVEHVLIDSGFKEIG
YAYSNYRRERTKIREIKSELMTAIEKIGVETDRDNANVGNNFSSKLLRIASESNKWYNLGVMPKHLAKLHENGDIYYHDL
DSYNLTVNCLNIDTGRILQRGFNTGYGTINAPKRIESAAELSCILLQSTQNDMFGGQAHVNFDNDMALFIPNTRSEIRKE
ILENLKGLEVQEEVLNKEKIDELVEERLRLRIHQAMQGIVYNLNTMHSRAGSQVPFSSINIGIPKNKDAALICEIFLKEY
EKGLGKGEQPIFPNIIFRVKEGVNREEKDPYYYLFKLAAKIAGKRMNPTFMNMDSDFNKEYYDKGIIPATMGCRTYVCSN
ISGEEGPAGRGNIAPTTINLPRVGILAKKDINKFFNLLDNRLELARESLLHRYNVLKKLRVKDLPFVVGEGLMKGSENLL
PDDSIEPILKQGSWAIGFIGIAETLTALIGSHHGETEEAKELGVKIVSHIRDFCDKYKEIDKLNWSCYATPAEGLSGKFI
LQDKKVFGEIKGVTDKNYYTNSYHIPVGFPISIKEKINIEAPYHKICNGGHISYIELDDYPSEEVIMDIIQYAYRNTNIS
YMGINFHIKYCRECGTYLGVEEEACNNCGSTNIQGISRVTGYLSLDERFGSGKVAERADRTSNNSSHRKIYNA

Sequences:

>Translated_713_residues
MLYVVKRDGRKVEIDVVKISNAIKGAAEEIAFDMKESENISLTQKVIKKIEDSNKEEISVEDIQNLVEHVLIDSGFKEIG
YAYSNYRRERTKIREIKSELMTAIEKIGVETDRDNANVGNNFSSKLLRIASESNKWYNLGVMPKHLAKLHENGDIYYHDL
DSYNLTVNCLNIDTGRILQRGFNTGYGTINAPKRIESAAELSCILLQSTQNDMFGGQAHVNFDNDMALFIPNTRSEIRKE
ILENLKGLEVQEEVLNKEKIDELVEERLRLRIHQAMQGIVYNLNTMHSRAGSQVPFSSINIGIPKNKDAALICEIFLKEY
EKGLGKGEQPIFPNIIFRVKEGVNREEKDPYYYLFKLAAKIAGKRMNPTFMNMDSDFNKEYYDKGIIPATMGCRTYVCSN
ISGEEGPAGRGNIAPTTINLPRVGILAKKDINKFFNLLDNRLELARESLLHRYNVLKKLRVKDLPFVVGEGLMKGSENLL
PDDSIEPILKQGSWAIGFIGIAETLTALIGSHHGETEEAKELGVKIVSHIRDFCDKYKEIDKLNWSCYATPAEGLSGKFI
LQDKKVFGEIKGVTDKNYYTNSYHIPVGFPISIKEKINIEAPYHKICNGGHISYIELDDYPSEEVIMDIIQYAYRNTNIS
YMGINFHIKYCRECGTYLGVEEEACNNCGSTNIQGISRVTGYLSLDERFGSGKVAERADRTSNNSSHRKIYNA
>Mature_713_residues
MLYVVKRDGRKVEIDVVKISNAIKGAAEEIAFDMKESENISLTQKVIKKIEDSNKEEISVEDIQNLVEHVLIDSGFKEIG
YAYSNYRRERTKIREIKSELMTAIEKIGVETDRDNANVGNNFSSKLLRIASESNKWYNLGVMPKHLAKLHENGDIYYHDL
DSYNLTVNCLNIDTGRILQRGFNTGYGTINAPKRIESAAELSCILLQSTQNDMFGGQAHVNFDNDMALFIPNTRSEIRKE
ILENLKGLEVQEEVLNKEKIDELVEERLRLRIHQAMQGIVYNLNTMHSRAGSQVPFSSINIGIPKNKDAALICEIFLKEY
EKGLGKGEQPIFPNIIFRVKEGVNREEKDPYYYLFKLAAKIAGKRMNPTFMNMDSDFNKEYYDKGIIPATMGCRTYVCSN
ISGEEGPAGRGNIAPTTINLPRVGILAKKDINKFFNLLDNRLELARESLLHRYNVLKKLRVKDLPFVVGEGLMKGSENLL
PDDSIEPILKQGSWAIGFIGIAETLTALIGSHHGETEEAKELGVKIVSHIRDFCDKYKEIDKLNWSCYATPAEGLSGKFI
LQDKKVFGEIKGVTDKNYYTNSYHIPVGFPISIKEKINIEAPYHKICNGGHISYIELDDYPSEEVIMDIIQYAYRNTNIS
YMGINFHIKYCRECGTYLGVEEEACNNCGSTNIQGISRVTGYLSLDERFGSGKVAERADRTSNNSSHRKIYNA

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=728, Percent_Identity=31.456043956044, Blast_Score=325, Evalue=7e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 80721; Mature: 80721

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYVVKRDGRKVEIDVVKISNAIKGAAEEIAFDMKESENISLTQKVIKKIEDSNKEEISV
CEEEEECCCCEEEEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEH
EDIQNLVEHVLIDSGFKEIGYAYSNYRRERTKIREIKSELMTAIEKIGVETDRDNANVGN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NFSSKLLRIASESNKWYNLGVMPKHLAKLHENGDIYYHDLDSYNLTVNCLNIDTGRILQR
CHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCEEEEECCCCEEEEEEEECCHHHHHHH
GFNTGYGTINAPKRIESAAELSCILLQSTQNDMFGGQAHVNFDNDMALFIPNTRSEIRKE
CCCCCCCCCCCCHHHHHHHHEEEEEEECCCCCCCCCEEEEECCCCEEEEECCCHHHHHHH
ILENLKGLEVQEEVLNKEKIDELVEERLRLRIHQAMQGIVYNLNTMHSRAGSQVPFSSIN
HHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
IGIPKNKDAALICEIFLKEYEKGLGKGEQPIFPNIIFRVKEGVNREEKDPYYYLFKLAAK
ECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
IAGKRMNPTFMNMDSDFNKEYYDKGIIPATMGCRTYVCSNISGEEGPAGRGNIAPTTINL
HHCCCCCCEEECCCCCCCHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEECC
PRVGILAKKDINKFFNLLDNRLELARESLLHRYNVLKKLRVKDLPFVVGEGLMKGSENLL
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
PDDSIEPILKQGSWAIGFIGIAETLTALIGSHHGETEEAKELGVKIVSHIRDFCDKYKEI
CCCCHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DKLNWSCYATPAEGLSGKFILQDKKVFGEIKGVTDKNYYTNSYHIPVGFPISIKEKINIE
HCCCCEEEECCCCCCCCEEEEECHHHHHHHCCCCCCCEECCEEEEECCCCEEECCCEECC
APYHKICNGGHISYIELDDYPSEEVIMDIIQYAYRNTNISYMGINFHIKYCRECGTYLGV
CCHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHCCC
EEEACNNCGSTNIQGISRVTGYLSLDERFGSGKVAERADRTSNNSSHRKIYNA
CHHHHCCCCCCCCCHHHHHHHHEEEHHHCCCCCHHHHHHCCCCCCCCCEECCC
>Mature Secondary Structure
MLYVVKRDGRKVEIDVVKISNAIKGAAEEIAFDMKESENISLTQKVIKKIEDSNKEEISV
CEEEEECCCCEEEEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEH
EDIQNLVEHVLIDSGFKEIGYAYSNYRRERTKIREIKSELMTAIEKIGVETDRDNANVGN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NFSSKLLRIASESNKWYNLGVMPKHLAKLHENGDIYYHDLDSYNLTVNCLNIDTGRILQR
CHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCEEEEECCCCEEEEEEEECCHHHHHHH
GFNTGYGTINAPKRIESAAELSCILLQSTQNDMFGGQAHVNFDNDMALFIPNTRSEIRKE
CCCCCCCCCCCCHHHHHHHHEEEEEEECCCCCCCCCEEEEECCCCEEEEECCCHHHHHHH
ILENLKGLEVQEEVLNKEKIDELVEERLRLRIHQAMQGIVYNLNTMHSRAGSQVPFSSIN
HHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
IGIPKNKDAALICEIFLKEYEKGLGKGEQPIFPNIIFRVKEGVNREEKDPYYYLFKLAAK
ECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
IAGKRMNPTFMNMDSDFNKEYYDKGIIPATMGCRTYVCSNISGEEGPAGRGNIAPTTINL
HHCCCCCCEEECCCCCCCHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEECC
PRVGILAKKDINKFFNLLDNRLELARESLLHRYNVLKKLRVKDLPFVVGEGLMKGSENLL
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
PDDSIEPILKQGSWAIGFIGIAETLTALIGSHHGETEEAKELGVKIVSHIRDFCDKYKEI
CCCCHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DKLNWSCYATPAEGLSGKFILQDKKVFGEIKGVTDKNYYTNSYHIPVGFPISIKEKINIE
HCCCCEEEECCCCCCCCEEEEECHHHHHHHCCCCCCCEECCEEEEECCCCEEECCCEECC
APYHKICNGGHISYIELDDYPSEEVIMDIIQYAYRNTNISYMGINFHIKYCRECGTYLGV
CCHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHCCC
EEEACNNCGSTNIQGISRVTGYLSLDERFGSGKVAERADRTSNNSSHRKIYNA
CHHHHCCCCCCCCCHHHHHHHHEEEHHHCCCCCHHHHHHCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]