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The map label for this gene is mrp [H]

Identifier: 226947312

GI number: 226947312

Start: 112895

End: 113737

Strand: Direct

Name: mrp [H]

Synonym: CLM_0131

Alternate gene names: 226947312

Gene position: 112895-113737 (Clockwise)

Preceding gene: 226947311

Following gene: 226947313

Centisome position: 2.72

GC content: 32.62

Gene sequence:

>843_bases
ATGAGTAATTGTGATAGCTGTGCTAGTAAAGGAACATGTAACAGTGAGGGAAGCTGCTCCAAGGAAACTTTTAAATATGG
AAATGCAAAAAATATCATAGGTGTAATTAGTGGAAAAGGTGGAGTAGGGAAATCAACAATAACGGGAATATTAGCTACTA
AATTAAGAGAAGAAGGCTATAAAGTAGGCGTATTAGATGGTGATATAACAGGGCCATCTATGCCAAGGTTTTTCGGTATT
AGTGATAAAAGAGCAACTATAATTCCAACGGGAGAAAATGAAGAAGTTAAAATAATACCCGTAGAAACCAAAACAGGAAT
AAAAGTAATGTCTTTAAATTTATTAACAGAACAAGAAGAAGCTCCTGTTATATGGAGAGGACCTGTAATAACAGGAGTTC
TGACTCAAATGTATACTGATACTGAGTGGGGTGAACTAGATTACTTACTTATAGATATGCCTCCGGGAACTGGTGACATA
GCATTAACTGTAATGCAAAGTTTACCTGTCACAAATATGGTGGTTGTTTCTACACCTCAAGATATGGTTTCTATGATAGT
TAAGAAAGTAGTTATAATGATAGAAAAAATGGGAATAGAGGTTTTAGGCGTAGTAGAAAATATGTCTTATATAAAATGTG
GAAGTTGTGGAGAAAAGCTAAATGTATTTAGTAAAAAGTCAGCAGAAGAACAAGCAGAATATCTAAATATACCACTAATA
GCAGATATGCCCATAAATCTTGATTTGTCTGAGGAAATGGAAAAGGGAGAAGTAGAGACATTTATTATAAATAATGAGGA
ATATGCTCAATTATATAATAACTTTAAAAATTTATATAAATAA

Upstream 100 bases:

>100_bases
TGCATTAAGATATGAATAAAGTTTAGGGCATTTGCTTATAACCTTATAAGTGATATAATTACACTATGAATTTACTTTGA
AATATATAGGAGGTTTTTTA

Downstream 100 bases:

>100_bases
TAATAAGGCTTCAATGAATATTCATTGAGGCCTTATTATTATTTATATTTAAAATATAGTTATGTTATCTTAGGAATAAA
AAAACTATAAAAGTTCAATA

Product: MRP protein-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSNCDSCASKGTCNSEGSCSKETFKYGNAKNIIGVISGKGGVGKSTITGILATKLREEGYKVGVLDGDITGPSMPRFFGI
SDKRATIIPTGENEEVKIIPVETKTGIKVMSLNLLTEQEEAPVIWRGPVITGVLTQMYTDTEWGELDYLLIDMPPGTGDI
ALTVMQSLPVTNMVVVSTPQDMVSMIVKKVVIMIEKMGIEVLGVVENMSYIKCGSCGEKLNVFSKKSAEEQAEYLNIPLI
ADMPINLDLSEEMEKGEVETFIINNEEYAQLYNNFKNLYK

Sequences:

>Translated_280_residues
MSNCDSCASKGTCNSEGSCSKETFKYGNAKNIIGVISGKGGVGKSTITGILATKLREEGYKVGVLDGDITGPSMPRFFGI
SDKRATIIPTGENEEVKIIPVETKTGIKVMSLNLLTEQEEAPVIWRGPVITGVLTQMYTDTEWGELDYLLIDMPPGTGDI
ALTVMQSLPVTNMVVVSTPQDMVSMIVKKVVIMIEKMGIEVLGVVENMSYIKCGSCGEKLNVFSKKSAEEQAEYLNIPLI
ADMPINLDLSEEMEKGEVETFIINNEEYAQLYNNFKNLYK
>Mature_279_residues
SNCDSCASKGTCNSEGSCSKETFKYGNAKNIIGVISGKGGVGKSTITGILATKLREEGYKVGVLDGDITGPSMPRFFGIS
DKRATIIPTGENEEVKIIPVETKTGIKVMSLNLLTEQEEAPVIWRGPVITGVLTQMYTDTEWGELDYLLIDMPPGTGDIA
LTVMQSLPVTNMVVVSTPQDMVSMIVKKVVIMIEKMGIEVLGVVENMSYIKCGSCGEKLNVFSKKSAEEQAEYLNIPLIA
DMPINLDLSEEMEKGEVETFIINNEEYAQLYNNFKNLYK

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=241, Percent_Identity=36.9294605809129, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI157384956, Length=245, Percent_Identity=35.5102040816327, Blast_Score=164, Evalue=6e-41,
Organism=Homo sapiens, GI118572611, Length=300, Percent_Identity=31.6666666666667, Blast_Score=153, Evalue=2e-37,
Organism=Escherichia coli, GI87082045, Length=248, Percent_Identity=42.3387096774194, Blast_Score=191, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI25143050, Length=290, Percent_Identity=34.4827586206897, Blast_Score=160, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6322188, Length=230, Percent_Identity=40, Blast_Score=166, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6321347, Length=272, Percent_Identity=30.8823529411765, Blast_Score=129, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24667611, Length=221, Percent_Identity=41.6289592760181, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI221511043, Length=246, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI19921440, Length=272, Percent_Identity=33.0882352941176, Blast_Score=131, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR000808 [H]

Pfam domain/function: PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 30610; Mature: 30479

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNCDSCASKGTCNSEGSCSKETFKYGNAKNIIGVISGKGGVGKSTITGILATKLREEGY
CCCCHHHHCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
KVGVLDGDITGPSMPRFFGISDKRATIIPTGENEEVKIIPVETKTGIKVMSLNLLTEQEE
EEEEEECCCCCCCCCCEECCCCCCEEEEECCCCCCEEEEEECCCCCEEEEEEEEEECCCC
APVIWRGPVITGVLTQMYTDTEWGELDYLLIDMPPGTGDIALTVMQSLPVTNMVVVSTPQ
CCEEEECCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHEEHHHCCCCEEEEEECCH
DMVSMIVKKVVIMIEKMGIEVLGVVENMSYIKCGSCGEKLNVFSKKSAEEQAEYLNIPLI
HHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCHHHHHHCCCHHHHHHHCCCCEE
ADMPINLDLSEEMEKGEVETFIINNEEYAQLYNNFKNLYK
ECCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNCDSCASKGTCNSEGSCSKETFKYGNAKNIIGVISGKGGVGKSTITGILATKLREEGY
CCCHHHHCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
KVGVLDGDITGPSMPRFFGISDKRATIIPTGENEEVKIIPVETKTGIKVMSLNLLTEQEE
EEEEEECCCCCCCCCCEECCCCCCEEEEECCCCCCEEEEEECCCCCEEEEEEEEEECCCC
APVIWRGPVITGVLTQMYTDTEWGELDYLLIDMPPGTGDIALTVMQSLPVTNMVVVSTPQ
CCEEEECCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHEEHHHCCCCEEEEEECCH
DMVSMIVKKVVIMIEKMGIEVLGVVENMSYIKCGSCGEKLNVFSKKSAEEQAEYLNIPLI
HHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCHHHHHHCCCHHHHHHHCCCCEE
ADMPINLDLSEEMEKGEVETFIINNEEYAQLYNNFKNLYK
ECCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842; 7559358 [H]