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The map label for this gene is macB [H]

Identifier: 226947311

GI number: 226947311

Start: 111605

End: 112813

Strand: Direct

Name: macB [H]

Synonym: CLM_0130

Alternate gene names: 226947311

Gene position: 111605-112813 (Clockwise)

Preceding gene: 226947310

Following gene: 226947312

Centisome position: 2.69

GC content: 29.86

Gene sequence:

>1209_bases
ATGAAATTTTTAGAAAATTTGAAAATGGCTTTAGATAGCATAAAATCAAATAAAATGCGATCTTTTTTAACTATGCTAGG
CATCATTATAGGAATAAGCTCTGTTATAACCATAGTATCTTTAGGAAAAGGTGGACAAAACACTATAACTGGCGAATTTG
AAAAAATAGGATCTGCTACAGTAAGTATAAAAGTAGATGGATCAAAGGCAAGCAGTAATGATTATATAAAGCAAGAAGAT
GTTGATATAATAAAGAATAAAATAGAAAAAGTTAAATATGTTGCACCAATAGTTTCAAGACCTGGATCTGTAACAGAAGG
AACAAAAAATAAAAAATTATATATAGATGGTTCAACTCCAGATGTACAGTATGTTACTAATGCTGAAATGGTTTATGGAA
GATTCTTCAATGAGGGAGAACATGTAGAAGGTAAACCTGTAGTTATAATAGATGAAAGATCAGCAAGAAATATTTTTGGA
ACAGAGGATGTAGTTGGAAGGAAACTAAAAATAAGTGCTAAAACATCTAGTAAACAGGTTACTGTTATAGGTGTCAGTAA
ATCAGAGTCAGGACCTTTTTCTGGGGGCGGTGAGGATAGTCCTATATTTTTAACGTGTCCTATAAATTTTTTAAAAGATT
TATATCCCGAGGATTTTATTATAGATAGTCTATATATTATAGCAACAGATAAAAATGATACTGAAGAAGTCGGAGTTATG
GCTAAAAATATATTAGAAAATAGACATCATAATAAAGGAAAAGATATGTATAAAGTTGAAAACATGTTAAAACAATTAGA
TGAAGTAAATAAAGTTATAGGAATATTTACTACATTTATTGGAGCAGTAGCAGCTATATCCTTATTAGTTGGGGGTATAG
GAGTTATGAATATAATGTTAGTATCCGTTACAGAAAGAACTAGAGAAATAGGGATAAGAAAAGCATTAGGGGCTACTACT
AAGAATATATTGATACAGTTTTTAACGGAATCTGTAATAATATCCTTAATAGGTGGGCTTATAGGAATGATACTAGGTAT
AGTATTTGCGGAAATTATAGGAAAGTTTATAAAGATATCTCCATCAGTATCTATAGCAGCTATACTCATAGCCATATTAT
TTTCTTCTTCTGTAGGAATATTTTTTGGTATATACCCAGCCAAAAAAGCAGCAAAGCTAAATCCAATAGATGCATTAAGA
TATGAATAA

Upstream 100 bases:

>100_bases
CTCATGAACCTGATATTGCTAAATATACTAAAAGAGTAGTTAAATTTAGAGATGGCCATATAGTATCAGATGAAAAAGTT
TTAAATAGGGAGATAGTAGA

Downstream 100 bases:

>100_bases
AGTTTAGGGCATTTGCTTATAACCTTATAAGTGATATAATTACACTATGAATTTACTTTGAAATATATAGGAGGTTTTTT
AATGAGTAATTGTGATAGCT

Product: putative macrolide efflux ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MKFLENLKMALDSIKSNKMRSFLTMLGIIIGISSVITIVSLGKGGQNTITGEFEKIGSATVSIKVDGSKASSNDYIKQED
VDIIKNKIEKVKYVAPIVSRPGSVTEGTKNKKLYIDGSTPDVQYVTNAEMVYGRFFNEGEHVEGKPVVIIDERSARNIFG
TEDVVGRKLKISAKTSSKQVTVIGVSKSESGPFSGGGEDSPIFLTCPINFLKDLYPEDFIIDSLYIIATDKNDTEEVGVM
AKNILENRHHNKGKDMYKVENMLKQLDEVNKVIGIFTTFIGAVAAISLLVGGIGVMNIMLVSVTERTREIGIRKALGATT
KNILIQFLTESVIISLIGGLIGMILGIVFAEIIGKFIKISPSVSIAAILIAILFSSSVGIFFGIYPAKKAAKLNPIDALR
YE

Sequences:

>Translated_402_residues
MKFLENLKMALDSIKSNKMRSFLTMLGIIIGISSVITIVSLGKGGQNTITGEFEKIGSATVSIKVDGSKASSNDYIKQED
VDIIKNKIEKVKYVAPIVSRPGSVTEGTKNKKLYIDGSTPDVQYVTNAEMVYGRFFNEGEHVEGKPVVIIDERSARNIFG
TEDVVGRKLKISAKTSSKQVTVIGVSKSESGPFSGGGEDSPIFLTCPINFLKDLYPEDFIIDSLYIIATDKNDTEEVGVM
AKNILENRHHNKGKDMYKVENMLKQLDEVNKVIGIFTTFIGAVAAISLLVGGIGVMNIMLVSVTERTREIGIRKALGATT
KNILIQFLTESVIISLIGGLIGMILGIVFAEIIGKFIKISPSVSIAAILIAILFSSSVGIFFGIYPAKKAAKLNPIDALR
YE
>Mature_402_residues
MKFLENLKMALDSIKSNKMRSFLTMLGIIIGISSVITIVSLGKGGQNTITGEFEKIGSATVSIKVDGSKASSNDYIKQED
VDIIKNKIEKVKYVAPIVSRPGSVTEGTKNKKLYIDGSTPDVQYVTNAEMVYGRFFNEGEHVEGKPVVIIDERSARNIFG
TEDVVGRKLKISAKTSSKQVTVIGVSKSESGPFSGGGEDSPIFLTCPINFLKDLYPEDFIIDSLYIIATDKNDTEEVGVM
AKNILENRHHNKGKDMYKVENMLKQLDEVNKVIGIFTTFIGAVAAISLLVGGIGVMNIMLVSVTERTREIGIRKALGATT
KNILIQFLTESVIISLIGGLIGMILGIVFAEIIGKFIKISPSVSIAAILIAILFSSSVGIFFGIYPAKKAAKLNPIDALR
YE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=417, Percent_Identity=34.2925659472422, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43645; Mature: 43645

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLENLKMALDSIKSNKMRSFLTMLGIIIGISSVITIVSLGKGGQNTITGEFEKIGSAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEE
VSIKVDGSKASSNDYIKQEDVDIIKNKIEKVKYVAPIVSRPGSVTEGTKNKKLYIDGSTP
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCC
DVQYVTNAEMVYGRFFNEGEHVEGKPVVIIDERSARNIFGTEDVVGRKLKISAKTSSKQV
CEEEEECCHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCHHHCCCEEEEEECCCCCEE
TVIGVSKSESGPFSGGGEDSPIFLTCPINFLKDLYPEDFIIDSLYIIATDKNDTEEVGVM
EEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHCCCCCEEECCEEEEEECCCCHHHHHHH
AKNILENRHHNKGKDMYKVENMLKQLDEVNKVIGIFTTFIGAVAAISLLVGGIGVMNIML
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVTERTREIGIRKALGATTKNILIQFLTESVIISLIGGLIGMILGIVFAEIIGKFIKIS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSVSIAAILIAILFSSSVGIFFGIYPAKKAAKLNPIDALRYE
CCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MKFLENLKMALDSIKSNKMRSFLTMLGIIIGISSVITIVSLGKGGQNTITGEFEKIGSAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEE
VSIKVDGSKASSNDYIKQEDVDIIKNKIEKVKYVAPIVSRPGSVTEGTKNKKLYIDGSTP
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCC
DVQYVTNAEMVYGRFFNEGEHVEGKPVVIIDERSARNIFGTEDVVGRKLKISAKTSSKQV
CEEEEECCHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCHHHCCCEEEEEECCCCCEE
TVIGVSKSESGPFSGGGEDSPIFLTCPINFLKDLYPEDFIIDSLYIIATDKNDTEEVGVM
EEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHCCCCCEEECCEEEEEECCCCHHHHHHH
AKNILENRHHNKGKDMYKVENMLKQLDEVNKVIGIFTTFIGAVAAISLLVGGIGVMNIML
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVTERTREIGIRKALGATTKNILIQFLTESVIISLIGGLIGMILGIVFAEIIGKFIKIS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSVSIAAILIAILFSSSVGIFFGIYPAKKAAKLNPIDALRYE
CCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA