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The map label for this gene is bmrR [H]

Identifier: 226225273

GI number: 226225273

Start: 2767831

End: 2768565

Strand: Direct

Name: bmrR [H]

Synonym: Lm4b_02696

Alternate gene names: 226225273

Gene position: 2767831-2768565 (Clockwise)

Preceding gene: 226225271

Following gene: 226225274

Centisome position: 95.03

GC content: 42.45

Gene sequence:

>735_bases
GTGGAACCGCTTTTTTCCATTGGGGAAATGGCAAAGAAAAGCCAACTCTCCATCCAACGACTGCGCTATTATGATAAAAT
TGGGCTTTTGGTCCCGGCTTTTACCGATCCAACTTCTGGATATCGCTACTACAAAACGGCTCAAGAAGAACAACTCAACC
TCATTCAAGCGTTGCAGTATATGGGGTTTTCCTTGCAAGAACTGAAACAATACCTCGACAAAAACACATCGGAAAGCTTG
CCCGATTTGCTTATAAAATACCAACAAAAATTAATGGATGAAGAAGCTCGCATTGCCCGTAAAAAATGGCTTATTGACCG
TTATCAAGGTTTGTTAAAACGGGAAACTGACACGACAAAACCTCTAACCGCGGTCCGACTTTTGCTTACAGAGCCACTTC
TAACGCCTGTTCATGCGGATATTTTAAACGACCCGGCTTTTCATCAAGAAGTGCAGAAAACCGTGAGCCGCCTTGGTCTT
TCGAAAAGCTATCAGCAGTTTCCTGGTTATTGTATTTTAGACGGGCAGACTTATCTTTTCATTGAGTTAGATCATTCTAT
TGGCGCGCCTGGTGAACGGCGTTTGTTATCAAGCGAGCGGCAAGCTTTTGTCACGCCGCAAAACTGGGAAACTCCTCTAG
AAAATGAAAATTACCTTTTACAAGAAACGGTGGCTTGGATTAATCAAGAGCTGGTTCGTGGTTATTCCTATGAAACAAAA
TTAACTTTTGAATAG

Upstream 100 bases:

>100_bases
TTTTTCCACAATAATTTTCATTTTTTTCACCTCTCGCTTTGAATTACCTTTATGATAAAGTGTATAGTAACTATAGAGTC
AAGACGAAAGGGTGATAAAT

Downstream 100 bases:

>100_bases
ATATTTTAGAAAGATTGGTTATAATAGAAAGAAATAACGTGGAGGTGGGCGCCGTGGAAATCAAGCAAATCAAAGCAAAA
GACACGCAAGATATTAGGCA

Product: merR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MEPLFSIGEMAKKSQLSIQRLRYYDKIGLLVPAFTDPTSGYRYYKTAQEEQLNLIQALQYMGFSLQELKQYLDKNTSESL
PDLLIKYQQKLMDEEARIARKKWLIDRYQGLLKRETDTTKPLTAVRLLLTEPLLTPVHADILNDPAFHQEVQKTVSRLGL
SKSYQQFPGYCILDGQTYLFIELDHSIGAPGERRLLSSERQAFVTPQNWETPLENENYLLQETVAWINQELVRGYSYETK
LTFE

Sequences:

>Translated_244_residues
MEPLFSIGEMAKKSQLSIQRLRYYDKIGLLVPAFTDPTSGYRYYKTAQEEQLNLIQALQYMGFSLQELKQYLDKNTSESL
PDLLIKYQQKLMDEEARIARKKWLIDRYQGLLKRETDTTKPLTAVRLLLTEPLLTPVHADILNDPAFHQEVQKTVSRLGL
SKSYQQFPGYCILDGQTYLFIELDHSIGAPGERRLLSSERQAFVTPQNWETPLENENYLLQETVAWINQELVRGYSYETK
LTFE
>Mature_244_residues
MEPLFSIGEMAKKSQLSIQRLRYYDKIGLLVPAFTDPTSGYRYYKTAQEEQLNLIQALQYMGFSLQELKQYLDKNTSESL
PDLLIKYQQKLMDEEARIARKKWLIDRYQGLLKRETDTTKPLTAVRLLLTEPLLTPVHADILNDPAFHQEVQKTVSRLGL
SKSYQQFPGYCILDGQTYLFIELDHSIGAPGERRLLSSERQAFVTPQNWETPLENENYLLQETVAWINQELVRGYSYETK
LTFE

Specific function: Activates transcription of the bmr gene in response to structurally dissimilar drugs. Binds rhodamine as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010499
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011256 [H]

Pfam domain/function: PF06445 AraC_E_bind; PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 28455; Mature: 28455

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLFSIGEMAKKSQLSIQRLRYYDKIGLLVPAFTDPTSGYRYYKTAQEEQLNLIQALQY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHCCHHHHHHHHHHHHH
MGFSLQELKQYLDKNTSESLPDLLIKYQQKLMDEEARIARKKWLIDRYQGLLKRETDTTK
HCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLTAVRLLLTEPLLTPVHADILNDPAFHQEVQKTVSRLGLSKSYQQFPGYCILDGQTYLF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCEEEE
IELDHSIGAPGERRLLSSERQAFVTPQNWETPLENENYLLQETVAWINQELVRGYSYETK
EEECCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
LTFE
EECC
>Mature Secondary Structure
MEPLFSIGEMAKKSQLSIQRLRYYDKIGLLVPAFTDPTSGYRYYKTAQEEQLNLIQALQY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHCCHHHHHHHHHHHHH
MGFSLQELKQYLDKNTSESLPDLLIKYQQKLMDEEARIARKKWLIDRYQGLLKRETDTTK
HCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLTAVRLLLTEPLLTPVHADILNDPAFHQEVQKTVSRLGLSKSYQQFPGYCILDGQTYLF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCEEEE
IELDHSIGAPGERRLLSSERQAFVTPQNWETPLENENYLLQETVAWINQELVRGYSYETK
EEECCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
LTFE
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7961792; 8969508; 9384377; 10568751; 10025401; 11201751 [H]