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The map label for this gene is isdF [H]

Identifier: 226224791

GI number: 226224791

Start: 2276409

End: 2277398

Strand: Reverse

Name: isdF [H]

Synonym: Lm4b_02209

Alternate gene names: 226224791

Gene position: 2277398-2276409 (Counterclockwise)

Preceding gene: 226224792

Following gene: 226224790

Centisome position: 78.19

GC content: 41.11

Gene sequence:

>990_bases
ATGACAATTAAGCAAAAAAGTTCTTTTGGGGCTGTAATTATTTTATTGATTGGGACTATTTTGTGGGCAGTTCAGGCGGG
AAGTTTGTCGATGTCGATTCCAGCTTTTTTGAGTGGGGTTTTTAGTGGCGGAAATGAGATGGTGAATGTCGTGATTGATT
TGCGATTTCCGCGGATTATTATTGCCCTGCTAGCTGGTGCGGCGCTATCGGTTTCAGGGTTGTTACTTCAAGCTGTGATG
CGGAATCCGCTTGCTGATGCTGGGGTGATTGGGATTTCTGCGGGTGCGAAATTTTTTAGTTTTGTGATTATTTTATTTTT
ACCGGAATTATATTTTTGGTTGCCACTTTTTTCTTTTATTGGGGGAGCACTGGCTTGTTTTCTAGTCTTTTTGTTTAGTT
ATCGTTCTGATTTTAATCCGCTTCGTTTTATTATTATTGGGATTGCGATTAATGCGGTTTTTACAGGGCTGAGTGATGCG
TTATCTTCGCAAGTGGCGCTTGTTTCTAGTCAGTCGGCCAGTAGTGCCGCAAGTTTGGCAATGAAAAAATGGTCCGACGT
GGAAACTTTATTGATATATGTAACGATTGGACTGATTTGCGCGCTTTTACTTGCTAAATGGTGCAATGTGTTGGGGCTTG
AGAATAAGATGGCTAGAGGCTTTGGTGTGCCGGTTAATAAGACACGTATTTGGCTGGCATTGATTGCTGTACTCCTTGCG
TCAATTACCACGGCGGTAGTTGGTGTTATTGCGTTTGTTGGTTTACTTGTACCACATATTGCCAGAAAACTAGTTGGCGG
AAATTATCAAATACTTGTGCCGTTTTCAATATTATTTGGGGCTTTATTGCTACTTTTCGCGGATACGCTAGGCAGAACGT
TATTTCAACAAATGGAAATCCCTGCGTCTGTGATTATGCTTATTATTGGTGGTCCGTTCTTAATCTTTTTAATGCGAAAG
GGTGATTTTTATGGAAGTAAGGGACGTTAA

Upstream 100 bases:

>100_bases
GTGAAAAATAATCGGGTGTATGATTTGGATGAAAATTTATTTGGTATGACAGCGAGTTTGAATGCACCAGAAGCACTACA
GGAAATGGAAAAGATGCTTT

Downstream 100 bases:

>100_bases
TTTTAGTTATAATGGAACGGATGCGATTTTAAAAAATGTCTCCTTTACTATCCAGAAAAATAAAATCAATACGATTGTTG
GGCCAAATGGTAGTGGGAAA

Product: ferrichrome ABC transporter (permease)

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron-regulated surface determinant protein F; Staphylococcal iron-regulated protein G [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTIKQKSSFGAVIILLIGTILWAVQAGSLSMSIPAFLSGVFSGGNEMVNVVIDLRFPRIIIALLAGAALSVSGLLLQAVM
RNPLADAGVIGISAGAKFFSFVIILFLPELYFWLPLFSFIGGALACFLVFLFSYRSDFNPLRFIIIGIAINAVFTGLSDA
LSSQVALVSSQSASSAASLAMKKWSDVETLLIYVTIGLICALLLAKWCNVLGLENKMARGFGVPVNKTRIWLALIAVLLA
SITTAVVGVIAFVGLLVPHIARKLVGGNYQILVPFSILFGALLLLFADTLGRTLFQQMEIPASVIMLIIGGPFLIFLMRK
GDFYGSKGR

Sequences:

>Translated_329_residues
MTIKQKSSFGAVIILLIGTILWAVQAGSLSMSIPAFLSGVFSGGNEMVNVVIDLRFPRIIIALLAGAALSVSGLLLQAVM
RNPLADAGVIGISAGAKFFSFVIILFLPELYFWLPLFSFIGGALACFLVFLFSYRSDFNPLRFIIIGIAINAVFTGLSDA
LSSQVALVSSQSASSAASLAMKKWSDVETLLIYVTIGLICALLLAKWCNVLGLENKMARGFGVPVNKTRIWLALIAVLLA
SITTAVVGVIAFVGLLVPHIARKLVGGNYQILVPFSILFGALLLLFADTLGRTLFQQMEIPASVIMLIIGGPFLIFLMRK
GDFYGSKGR
>Mature_328_residues
TIKQKSSFGAVIILLIGTILWAVQAGSLSMSIPAFLSGVFSGGNEMVNVVIDLRFPRIIIALLAGAALSVSGLLLQAVMR
NPLADAGVIGISAGAKFFSFVIILFLPELYFWLPLFSFIGGALACFLVFLFSYRSDFNPLRFIIIGIAINAVFTGLSDAL
SSQVALVSSQSASSAASLAMKKWSDVETLLIYVTIGLICALLLAKWCNVLGLENKMARGFGVPVNKTRIWLALIAVLLAS
ITTAVVGVIAFVGLLVPHIARKLVGGNYQILVPFSILFGALLLLFADTLGRTLFQQMEIPASVIMLIIGGPFLIFLMRKG
DFYGSKGR

Specific function: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=311, Percent_Identity=33.1189710610932, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786347, Length=274, Percent_Identity=33.2116788321168, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786805, Length=299, Percent_Identity=35.7859531772575, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790741, Length=283, Percent_Identity=31.8021201413428, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786804, Length=301, Percent_Identity=31.2292358803987, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788004, Length=275, Percent_Identity=29.4545454545455, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35188; Mature: 35057

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKQKSSFGAVIILLIGTILWAVQAGSLSMSIPAFLSGVFSGGNEMVNVVIDLRFPRII
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHEEHEEECHHHHHH
IALLAGAALSVSGLLLQAVMRNPLADAGVIGISAGAKFFSFVIILFLPELYFWLPLFSFI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGALACFLVFLFSYRSDFNPLRFIIIGIAINAVFTGLSDALSSQVALVSSQSASSAASLA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MKKWSDVETLLIYVTIGLICALLLAKWCNVLGLENKMARGFGVPVNKTRIWLALIAVLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHH
SITTAVVGVIAFVGLLVPHIARKLVGGNYQILVPFSILFGALLLLFADTLGRTLFQQMEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
PASVIMLIIGGPFLIFLMRKGDFYGSKGR
CHHHHHHHHCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TIKQKSSFGAVIILLIGTILWAVQAGSLSMSIPAFLSGVFSGGNEMVNVVIDLRFPRII
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHEEHEEECHHHHHH
IALLAGAALSVSGLLLQAVMRNPLADAGVIGISAGAKFFSFVIILFLPELYFWLPLFSFI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGALACFLVFLFSYRSDFNPLRFIIIGIAINAVFTGLSDALSSQVALVSSQSASSAASLA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MKKWSDVETLLIYVTIGLICALLLAKWCNVLGLENKMARGFGVPVNKTRIWLALIAVLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHH
SITTAVVGVIAFVGLLVPHIARKLVGGNYQILVPFSILFGALLLLFADTLGRTLFQQMEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
PASVIMLIIGGPFLIFLMRKGDFYGSKGR
CHHHHHHHHCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA