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The map label for this gene is ydiF [H]

Identifier: 226224779

GI number: 226224779

Start: 2254276

End: 2255859

Strand: Reverse

Name: ydiF [H]

Synonym: Lm4b_02197

Alternate gene names: 226224779

Gene position: 2255859-2254276 (Counterclockwise)

Preceding gene: 226224780

Following gene: 226224778

Centisome position: 77.45

GC content: 40.09

Gene sequence:

>1584_bases
TTGTCAAAAGTAATAAAAGCTAGTGAAGCAGCAAAATTATTAAAAGATGGCGATACTGTTGCTTTTAGTGGTTTCGGTTT
AGCTTGTGTTAATGAAGAAATGGCTATCGCGGTTGAAAAGCGTTTTTTAGAAGAAGGGGCACCGCGTAATCTAACAGTTA
TGCATGCTAGTGCGCTTGGTGATCGCAGGGAAAAAGGAATGAGTCACTGGGGACATGAAGGATTAATTAAACGCTGGATT
GGCGGAATTGCGATTGCTTCTCCTAAAATGGCGAAACTAATTGAAGAAGACAAATGTGAAGCATACAATTTACCACAAGG
TGTAATTACGCAATTGTATCGTGAAATTGCAGCTAAACGGCCAGGCGTGATTACAAAAATTGGCATGGGAACATTTGTAG
ATCCACGTATTGAAGGGGCAAAAATGTCTGCGAGTTCTAAAGACAACTTAGTAGAGCTATTGACGATTCACGACGAAGAA
TGGCTATTTTATACAAGTTTCCCAATTCAAGTTGCGCTCATTCGAGGAACTGTGGCAGATGAATTTGGGAACTTAACGTT
AGAAAAAGAAGGCTTACATATGGAAGTCTTACCAATTGCACAGGCAGTTCGAAATTCAGGCGGAATTGTAATCGCTCAAG
TAGAATCTGTTGCGAAAAAAGGATCGCTTAATCCTAAAGATGTTAGAGTTCCAGGAATTTTGGTTGATCATATTATTATT
TCAGAACCGGAAAATCATTTTCAAACTGAAAATACACAGTACAACCCAGCTTTTTCAGGGCATATTCAAGTTCCGCTTGG
AGATATTGAGCCACTTCCGTTAGATGACCGTAAAGTAATTGCGCGTCGTTCAGCAGCAGAACTAGAACCACAAACTATTC
TAAATTTAGGTGTAGGAATTCCGGTGAACGTATCAACTGTAGCAGCGGAAGAGGGCGTGAGTGATCAATTAATACTAACA
ACGGAAGCTGGTTCTGTTGGTGGTGTTCCAGCAGGTTTAGCAGATTTCGGCCATGCTTATAACAGTGAAGCTATTGTCGA
TCATCATTCGCAGTTCGATTTTTACGATGGTGGAGGACTCGATTTATCCGTACTTGGTTTGGCGCAAACCGACGAATCCG
GTAATGTGAATGTCAGCAAGTTTGGCTCAAGAGTTGCTGGCTGCGGTGGATTTATTAATATCTCCCAATCAGCGAAAAAA
TTAATTTTTGCCGGAACTTTTACAGCAGGTGGATTAAAGACGCGTGTAGCTGACGGAAAATTAGAGATTTTACAAGAAGG
AAAAGCTAAAAAGTTTATCAAACAAGTTCAACAAATCACATTTAGTGGCGAATACGCTTCAACGACCGACCAAATCATCC
TCTATGTGACAGAGCGAGCTGTATTCCGTTTAGAAAATGGCAAAATGGTTCTAACAGAAATCGCGCCAGGAGTAGATTTA
GAAAAAGATATCCTTGGACAAATGGAATTCGAACCTGTTATTGCGAGTGATTTAAAAGTAATGGATAGCGGTATGTTTAG
TGAACAATGGGGCGGCTTAAAAACTATTATTGAAAAACAAACAAGAGAGGGAGTATCTATATGA

Upstream 100 bases:

>100_bases
TTATAGAGCTATTTTTGATGTTGGCACGGAAGTTGCTTTATAAAGAACTGCATGTCATTACAAATATATGTGAATAATTG
AACAATGAGGAGTGAGGAAT

Downstream 100 bases:

>100_bases
CAAAAGAAATAAACCGTTGGGGAGTCTTAATTGGCTCTGTTGGTGTTCTGCTTTGTACCGGTGCGGTATATGCATTTAGT
GTTTTTGCTGGACCGCTAAG

Product: propionate CoA-transferase

Products: acetate; propanoyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MSKVIKASEAAKLLKDGDTVAFSGFGLACVNEEMAIAVEKRFLEEGAPRNLTVMHASALGDRREKGMSHWGHEGLIKRWI
GGIAIASPKMAKLIEEDKCEAYNLPQGVITQLYREIAAKRPGVITKIGMGTFVDPRIEGAKMSASSKDNLVELLTIHDEE
WLFYTSFPIQVALIRGTVADEFGNLTLEKEGLHMEVLPIAQAVRNSGGIVIAQVESVAKKGSLNPKDVRVPGILVDHIII
SEPENHFQTENTQYNPAFSGHIQVPLGDIEPLPLDDRKVIARRSAAELEPQTILNLGVGIPVNVSTVAAEEGVSDQLILT
TEAGSVGGVPAGLADFGHAYNSEAIVDHHSQFDFYDGGGLDLSVLGLAQTDESGNVNVSKFGSRVAGCGGFINISQSAKK
LIFAGTFTAGGLKTRVADGKLEILQEGKAKKFIKQVQQITFSGEYASTTDQIILYVTERAVFRLENGKMVLTEIAPGVDL
EKDILGQMEFEPVIASDLKVMDSGMFSEQWGGLKTIIEKQTREGVSI

Sequences:

>Translated_527_residues
MSKVIKASEAAKLLKDGDTVAFSGFGLACVNEEMAIAVEKRFLEEGAPRNLTVMHASALGDRREKGMSHWGHEGLIKRWI
GGIAIASPKMAKLIEEDKCEAYNLPQGVITQLYREIAAKRPGVITKIGMGTFVDPRIEGAKMSASSKDNLVELLTIHDEE
WLFYTSFPIQVALIRGTVADEFGNLTLEKEGLHMEVLPIAQAVRNSGGIVIAQVESVAKKGSLNPKDVRVPGILVDHIII
SEPENHFQTENTQYNPAFSGHIQVPLGDIEPLPLDDRKVIARRSAAELEPQTILNLGVGIPVNVSTVAAEEGVSDQLILT
TEAGSVGGVPAGLADFGHAYNSEAIVDHHSQFDFYDGGGLDLSVLGLAQTDESGNVNVSKFGSRVAGCGGFINISQSAKK
LIFAGTFTAGGLKTRVADGKLEILQEGKAKKFIKQVQQITFSGEYASTTDQIILYVTERAVFRLENGKMVLTEIAPGVDL
EKDILGQMEFEPVIASDLKVMDSGMFSEQWGGLKTIIEKQTREGVSI
>Mature_526_residues
SKVIKASEAAKLLKDGDTVAFSGFGLACVNEEMAIAVEKRFLEEGAPRNLTVMHASALGDRREKGMSHWGHEGLIKRWIG
GIAIASPKMAKLIEEDKCEAYNLPQGVITQLYREIAAKRPGVITKIGMGTFVDPRIEGAKMSASSKDNLVELLTIHDEEW
LFYTSFPIQVALIRGTVADEFGNLTLEKEGLHMEVLPIAQAVRNSGGIVIAQVESVAKKGSLNPKDVRVPGILVDHIIIS
EPENHFQTENTQYNPAFSGHIQVPLGDIEPLPLDDRKVIARRSAAELEPQTILNLGVGIPVNVSTVAAEEGVSDQLILTT
EAGSVGGVPAGLADFGHAYNSEAIVDHHSQFDFYDGGGLDLSVLGLAQTDESGNVNVSKFGSRVAGCGGFINISQSAKKL
IFAGTFTAGGLKTRVADGKLEILQEGKAKKFIKQVQQITFSGEYASTTDQIILYVTERAVFRLENGKMVLTEIAPGVDLE
KDILGQMEFEPVIASDLKVMDSGMFSEQWGGLKTIIEKQTREGVSI

Specific function: Unknown

COG id: COG4670

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae AtoD [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=500, Percent_Identity=24, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI11545841, Length=508, Percent_Identity=24.0157480314961, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1787985, Length=504, Percent_Identity=44.047619047619, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1788552, Length=239, Percent_Identity=30.9623430962343, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788551, Length=245, Percent_Identity=25.3061224489796, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17531517, Length=417, Percent_Identity=23.7410071942446, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24655794, Length=517, Percent_Identity=24.3713733075435, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21358325, Length=517, Percent_Identity=24.3713733075435, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014388
- InterPro:   IPR004165 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: 2.8.3.1

Molecular weight: Translated: 56873; Mature: 56742

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVIKASEAAKLLKDGDTVAFSGFGLACVNEEMAIAVEKRFLEEGAPRNLTVMHASALG
CCCCHHHHHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEEHHHHC
DRREKGMSHWGHEGLIKRWIGGIAIASPKMAKLIEEDKCEAYNLPQGVITQLYREIAAKR
HHHHHHHHHCCHHHHHHHHHCCEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
PGVITKIGMGTFVDPRIEGAKMSASSKDNLVELLTIHDEEWLFYTSFPIQVALIRGTVAD
CCCEEEECCCCCCCCCCCCCEECCCCCCCEEEEEEEECCCEEEEECCCEEEEEEECHHHH
EFGNLTLEKEGLHMEVLPIAQAVRNSGGIVIAQVESVAKKGSLNPKDVRVPGILVDHIII
HHCCEEEECCCCEEEEHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCEECCCEEEEEEEE
SEPENHFQTENTQYNPAFSGHIQVPLGDIEPLPLDDRKVIARRSAAELEPQTILNLGVGI
CCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCHHHCCCHHHHHCCCCC
PVNVSTVAAEEGVSDQLILTTEAGSVGGVPAGLADFGHAYNSEAIVDHHSQFDFYDGGGL
CCCEEEEHHCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCCEEECCCCCCEECCCCC
DLSVLGLAQTDESGNVNVSKFGSRVAGCGGFINISQSAKKLIFAGTFTAGGLKTRVADGK
EEEEEEEEECCCCCCEEHHHHCCHHHCCCCEEECCCCCCEEEEEEEECCCCCEEEECCCH
LEILQEGKAKKFIKQVQQITFSGEYASTTDQIILYVTERAVFRLENGKMVLTEIAPGVDL
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEECCCCEEEEECCCCCCC
EKDILGQMEFEPVIASDLKVMDSGMFSEQWGGLKTIIEKQTREGVSI
CHHHHCCCCCCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKVIKASEAAKLLKDGDTVAFSGFGLACVNEEMAIAVEKRFLEEGAPRNLTVMHASALG
CCCHHHHHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEEHHHHC
DRREKGMSHWGHEGLIKRWIGGIAIASPKMAKLIEEDKCEAYNLPQGVITQLYREIAAKR
HHHHHHHHHCCHHHHHHHHHCCEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
PGVITKIGMGTFVDPRIEGAKMSASSKDNLVELLTIHDEEWLFYTSFPIQVALIRGTVAD
CCCEEEECCCCCCCCCCCCCEECCCCCCCEEEEEEEECCCEEEEECCCEEEEEEECHHHH
EFGNLTLEKEGLHMEVLPIAQAVRNSGGIVIAQVESVAKKGSLNPKDVRVPGILVDHIII
HHCCEEEECCCCEEEEHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCEECCCEEEEEEEE
SEPENHFQTENTQYNPAFSGHIQVPLGDIEPLPLDDRKVIARRSAAELEPQTILNLGVGI
CCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCHHHCCCHHHHHCCCCC
PVNVSTVAAEEGVSDQLILTTEAGSVGGVPAGLADFGHAYNSEAIVDHHSQFDFYDGGGL
CCCEEEEHHCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCCEEECCCCCCEECCCCC
DLSVLGLAQTDESGNVNVSKFGSRVAGCGGFINISQSAKKLIFAGTFTAGGLKTRVADGK
EEEEEEEEECCCCCCEEHHHHCCHHHCCCCEEECCCCCCEEEEEEEECCCCCEEEECCCH
LEILQEGKAKKFIKQVQQITFSGEYASTTDQIILYVTERAVFRLENGKMVLTEIAPGVDL
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEECCCCEEEEECCCCCCC
EKDILGQMEFEPVIASDLKVMDSGMFSEQWGGLKTIIEKQTREGVSI
CHHHHCCCCCCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acetyl-CoA; propanoate

Specific reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 3541912; 7984428 [H]