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The map label for this gene is frwB [H]

Identifier: 226224743

GI number: 226224743

Start: 2221920

End: 2222231

Strand: Reverse

Name: frwB [H]

Synonym: Lm4b_02160

Alternate gene names: 226224743

Gene position: 2222231-2221920 (Counterclockwise)

Preceding gene: 226224744

Following gene: 226224742

Centisome position: 76.29

GC content: 35.26

Gene sequence:

>312_bases
ATGAATATTATTGGAATAGCAGCTTGTACATCGGGAATCGCACATACGTATATTGCTAAAGAAAAACTAACAAAAGCAGG
GACAGCGCTTGGTCACAACGTTCATATTGAAACACAAGGAACAATTGGTATCGAAGACGAGCTTTCAGCAGAACAAGTGA
AAAATGCCGATGTAGTTATTATTGCTGCCGATATTAAAATTAGCGGAAAGGATCGTTTTAAAGGAAAACGAGTTGTCGAA
ATTCCAACAGACCTAGCGATTAAAGCACCAAAACAAATTATTAATAAAATAGACAAAGAAATAAATAACTAG

Upstream 100 bases:

>100_bases
ACTTGCGGACGATGAGGTGATTGGCCAATTTCAAACTGTAAAAACAAAAGAAGATTTAATTAAGTTGTTAGCCAAAAATC
AGGATTAGGAGGAGTTTGGA

Downstream 100 bases:

>100_bases
GGAGTGAACCGGTATGATGAAAAAACTGCAAATCAAAAAACATGCACTTACAGCGATTTCGTATATGTTACCGTTAGTTG
TTGCCTCGGGGTTACTTATT

Product: PTS system, fructose-specific enzyme IIB component

Products: NA

Alternate protein names: PTS system fructose-like EIIB component 2 [H]

Number of amino acids: Translated: 103; Mature: 103

Protein sequence:

>103_residues
MNIIGIAACTSGIAHTYIAKEKLTKAGTALGHNVHIETQGTIGIEDELSAEQVKNADVVIIAADIKISGKDRFKGKRVVE
IPTDLAIKAPKQIINKIDKEINN

Sequences:

>Translated_103_residues
MNIIGIAACTSGIAHTYIAKEKLTKAGTALGHNVHIETQGTIGIEDELSAEQVKNADVVIIAADIKISGKDRFKGKRVVE
IPTDLAIKAPKQIINKIDKEINN
>Mature_103_residues
MNIIGIAACTSGIAHTYIAKEKLTKAGTALGHNVHIETQGTIGIEDELSAEQVKNADVVIIAADIKISGKDRFKGKRVVE
IPTDLAIKAPKQIINKIDKEINN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1445

COG function: function code G; Phosphotransferase system fructose-specific component IIB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790387, Length=96, Percent_Identity=47.9166666666667, Blast_Score=92, Evalue=4e-21,
Organism=Escherichia coli, GI87082348, Length=99, Percent_Identity=42.4242424242424, Blast_Score=88, Evalue=1e-19,
Organism=Escherichia coli, GI1786951, Length=94, Percent_Identity=41.4893617021277, Blast_Score=81, Evalue=1e-17,
Organism=Escherichia coli, GI1790390, Length=100, Percent_Identity=34, Blast_Score=81, Evalue=1e-17,
Organism=Escherichia coli, GI1788730, Length=99, Percent_Identity=35.3535353535354, Blast_Score=67, Evalue=2e-13,
Organism=Escherichia coli, GI1788492, Length=94, Percent_Identity=35.1063829787234, Blast_Score=65, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003353 [H]

Pfam domain/function: PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 11045; Mature: 11045

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIGIAACTSGIAHTYIAKEKLTKAGTALGHNVHIETQGTIGIEDELSAEQVKNADVVI
CCEEEEEHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHCCCCCEEE
IAADIKISGKDRFKGKRVVEIPTDLAIKAPKQIINKIDKEINN
EEECEEECCCCCCCCCEEEECCCCCEEECHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIIGIAACTSGIAHTYIAKEKLTKAGTALGHNVHIETQGTIGIEDELSAEQVKNADVVI
CCEEEEEHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHCCCCCEEE
IAADIKISGKDRFKGKRVVEIPTDLAIKAPKQIINKIDKEINN
EEECEEECCCCCCCCCEEEECCCCCEEECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]