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The map label for this gene is mdxF [H]

Identifier: 226224731

GI number: 226224731

Start: 2206772

End: 2208079

Strand: Reverse

Name: mdxF [H]

Synonym: Lm4b_02148

Alternate gene names: 226224731

Gene position: 2208079-2206772 (Counterclockwise)

Preceding gene: 226224732

Following gene: 226224730

Centisome position: 75.81

GC content: 37.31

Gene sequence:

>1308_bases
ATGAAACTAGAACAAAAACAAATTAAAAATGTTCGTCAAGCGACTTTGTTATCAATCATTCCGGGACTTGGTCAATTTTA
TAATAAGCAAAATTTTAAAGGGATTGTCTTTTTCGCACTATTTGCTTTGTTTATCATAGAATTTTTTGCAGTTGGGCTGA
ATGCACTGATTGGCCTTGTAACACTTGGATCTGTACCGGGTGTAGACCATTCCTTATTTTTAATGATTGAAGGTACTTTA
CAATTAATTGTGACATTACTATTTATAGGCTTTTGGTTTATAAATATTTTCGATGCAAGACGCGTGGCTATGCAGTGGAA
CCTAGGTGAAACTGTTAACCGTTCTGCGATTGCTATTATAAAAAATATGCTCGACAAAGGTTTCCCGTACTTACTTACAT
TACCTGCATACTTAGTGATGACTTTTGTTATTATTTTCCCAGTTCTTGTTACTCTTTTCATGGCATTTACCAACTATGAT
TTTTACCATATTCCGCCAGCGAACTTAATTGACTGGGTTGGATTTAAGAACTTCTTTAATATTTTCTTCCTAAGTTCGTA
TCGTGACACGTTCCTAAGCGTATTTTCGTGGACACTCATTTGGACAATCTGTGCCACTTCTTTACAAATTGTCGTTGGTG
TATTCACGGCGATTGTTGCGAACCAAAGCTTTATTAAAGGGAAACGTCTTTTTGGGGTAGTTTTCTTACTTCCTTGGGCG
GTACCAGCATTTATTACAATTATGAGTTTTTCCAATATGTTTAACGACAGTATTGGCGCAATCAACTCGCAAGTCATTCC
ACTTCTAAACCATTTGCCATTTGTTGATATCAATGCGATTGCTTGGAAAACAGATCCTTTCTGGACAAAAGTGGCGCTGA
TTAGTATTCAAGGTTGGCTTGGTTTTCCGTATATTTACGTTATGGTTACTGGGGTGCTTCAAGCAATTCCTGGTGAACTA
TACGAAGCAGCTAGAATTGATGGTGCAAGTGCGATTCAACGTTTCCGTAAAATTACATTACCGATGATTTTATTTGTAAC
CGCGCCGGTATTTATTACGCAATATACATTTAACTTCAACAACTTTTCGATAATATACTTATTCAATGAAGGTGGTCCCG
GAAGTGTCGGAGCAGGCGCAGGATCAACCGATATCTTAATTTCATGGATTTATAAATTAACAACAGGTACTTCGCCACAA
TACGCTGTAGCTGCTGCTGTGACGCTTCTTATCTCTATTATCGTTATTACTGTTTCGATGATTGCCTTTAAGAAGACGAA
TGCCTTTGGGAACGAGGAGATGATGTAA

Upstream 100 bases:

>100_bases
ATATACTAAATAATAATGATTTGGCGGGGCAAAGATAGCGCGCTCCGCCATTTTTTTCAACTTAGCTAGTGAATCTATAT
CTAGAATTGAGGGTAACAAA

Downstream 100 bases:

>100_bases
ATGAGAGACTTTATGAAAGATCAGCGGACAACAAAGTTCTTAACACAGTTTTTCACGTATTTGTTTTTAACCGTGCTAAC
GATTATTATTTTGTATCCGA

Product: maltodextrin ABC-transport system (permease)

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MKLEQKQIKNVRQATLLSIIPGLGQFYNKQNFKGIVFFALFALFIIEFFAVGLNALIGLVTLGSVPGVDHSLFLMIEGTL
QLIVTLLFIGFWFINIFDARRVAMQWNLGETVNRSAIAIIKNMLDKGFPYLLTLPAYLVMTFVIIFPVLVTLFMAFTNYD
FYHIPPANLIDWVGFKNFFNIFFLSSYRDTFLSVFSWTLIWTICATSLQIVVGVFTAIVANQSFIKGKRLFGVVFLLPWA
VPAFITIMSFSNMFNDSIGAINSQVIPLLNHLPFVDINAIAWKTDPFWTKVALISIQGWLGFPYIYVMVTGVLQAIPGEL
YEAARIDGASAIQRFRKITLPMILFVTAPVFITQYTFNFNNFSIIYLFNEGGPGSVGAGAGSTDILISWIYKLTTGTSPQ
YAVAAAVTLLISIIVITVSMIAFKKTNAFGNEEMM

Sequences:

>Translated_435_residues
MKLEQKQIKNVRQATLLSIIPGLGQFYNKQNFKGIVFFALFALFIIEFFAVGLNALIGLVTLGSVPGVDHSLFLMIEGTL
QLIVTLLFIGFWFINIFDARRVAMQWNLGETVNRSAIAIIKNMLDKGFPYLLTLPAYLVMTFVIIFPVLVTLFMAFTNYD
FYHIPPANLIDWVGFKNFFNIFFLSSYRDTFLSVFSWTLIWTICATSLQIVVGVFTAIVANQSFIKGKRLFGVVFLLPWA
VPAFITIMSFSNMFNDSIGAINSQVIPLLNHLPFVDINAIAWKTDPFWTKVALISIQGWLGFPYIYVMVTGVLQAIPGEL
YEAARIDGASAIQRFRKITLPMILFVTAPVFITQYTFNFNNFSIIYLFNEGGPGSVGAGAGSTDILISWIYKLTTGTSPQ
YAVAAAVTLLISIIVITVSMIAFKKTNAFGNEEMM
>Mature_435_residues
MKLEQKQIKNVRQATLLSIIPGLGQFYNKQNFKGIVFFALFALFIIEFFAVGLNALIGLVTLGSVPGVDHSLFLMIEGTL
QLIVTLLFIGFWFINIFDARRVAMQWNLGETVNRSAIAIIKNMLDKGFPYLLTLPAYLVMTFVIIFPVLVTLFMAFTNYD
FYHIPPANLIDWVGFKNFFNIFFLSSYRDTFLSVFSWTLIWTICATSLQIVVGVFTAIVANQSFIKGKRLFGVVFLLPWA
VPAFITIMSFSNMFNDSIGAINSQVIPLLNHLPFVDINAIAWKTDPFWTKVALISIQGWLGFPYIYVMVTGVLQAIPGEL
YEAARIDGASAIQRFRKITLPMILFVTAPVFITQYTFNFNNFSIIYLFNEGGPGSVGAGAGSTDILISWIYKLTTGTSPQ
YAVAAAVTLLISIIVITVSMIAFKKTNAFGNEEMM

Specific function: Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790465, Length=259, Percent_Identity=35.9073359073359, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1787570, Length=237, Percent_Identity=29.535864978903, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789861, Length=309, Percent_Identity=27.5080906148867, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 48661; Mature: 48661

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEQKQIKNVRQATLLSIIPGLGQFYNKQNFKGIVFFALFALFIIEFFAVGLNALIGLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGSVPGVDHSLFLMIEGTLQLIVTLLFIGFWFINIFDARRVAMQWNLGETVNRSAIAII
HHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHH
KNMLDKGFPYLLTLPAYLVMTFVIIFPVLVTLFMAFTNYDFYHIPPANLIDWVGFKNFFN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHH
IFFLSSYRDTFLSVFSWTLIWTICATSLQIVVGVFTAIVANQSFIKGKRLFGVVFLLPWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VPAFITIMSFSNMFNDSIGAINSQVIPLLNHLPFVDINAIAWKTDPFWTKVALISIQGWL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECEEEECCCCCHHEEEEEEEECHH
GFPYIYVMVTGVLQAIPGELYEAARIDGASAIQRFRKITLPMILFVTAPVFITQYTFNFN
HHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC
NFSIIYLFNEGGPGSVGAGAGSTDILISWIYKLTTGTSPQYAVAAAVTLLISIIVITVSM
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
IAFKKTNAFGNEEMM
HHHHHCCCCCCCCCC
>Mature Secondary Structure
MKLEQKQIKNVRQATLLSIIPGLGQFYNKQNFKGIVFFALFALFIIEFFAVGLNALIGLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGSVPGVDHSLFLMIEGTLQLIVTLLFIGFWFINIFDARRVAMQWNLGETVNRSAIAII
HHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHH
KNMLDKGFPYLLTLPAYLVMTFVIIFPVLVTLFMAFTNYDFYHIPPANLIDWVGFKNFFN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHH
IFFLSSYRDTFLSVFSWTLIWTICATSLQIVVGVFTAIVANQSFIKGKRLFGVVFLLPWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VPAFITIMSFSNMFNDSIGAINSQVIPLLNHLPFVDINAIAWKTDPFWTKVALISIQGWL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECEEEECCCCCHHEEEEEEEECHH
GFPYIYVMVTGVLQAIPGELYEAARIDGASAIQRFRKITLPMILFVTAPVFITQYTFNFN
HHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC
NFSIIYLFNEGGPGSVGAGAGSTDILISWIYKLTTGTSPQYAVAAAVTLLISIIVITVSM
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
IAFKKTNAFGNEEMM
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]