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The map label for this gene is glmM

Identifier: 226224724

GI number: 226224724

Start: 2197422

End: 2198774

Strand: Reverse

Name: glmM

Synonym: Lm4b_02140

Alternate gene names: 226224724

Gene position: 2198774-2197422 (Counterclockwise)

Preceding gene: 226224725

Following gene: 226224722

Centisome position: 75.49

GC content: 39.1

Gene sequence:

>1353_bases
ATGGGTAAATATTTTGGTACGGATGGAGTTAGAGGTGTTGCAAACTCTGAATTAACACCAGAACTTGCATTCAGATTAGG
TAGAATGGGTGGGTATGTTTTAACCCGTCACGTAGGGGAACATCCACGTGTTCTTGTAGCTCGTGATACACGTATATCTG
GAGAAATGCTTGAATCCGCTTTAATCGCAGGACTTGTTTCTGTAGGGATTGAAGTAATGCGTCTAGGAGTTATCTCCACA
CCAGGTGTAGCTTATTTAACAAAAGCACAAGGCGCTTCTGCTAGTGTAATGATCTCCGCCAGCCATAATCCAGTGGATGA
TAACGGTATTAAATTCTTTGGTTCTGACGGCTTTAAATTGTCAGATGATCAGGAAGAAGAAATTGAACAGCTTCTTGATA
CAGCAGAAGATACGCTACCTCGACCAAGTGGAGAAGGTCTTGGGACAGTGAGCGATTATTTTGAAGGCAAACAAAAATAT
ATTCAATACTTGAAACAAACAATCGAAAATGACTTTAATGGATATCACATTGCACTTGATTGTGCGAATGGTGCAACTTC
AGGTCTTGCAACGCATTTATTTGCAGATTTAGATGCGGATATTAGTTCGATGGGAGCGTCTCCAAACGGTTTAAATATCA
ATGATGGCGTCGGATCTACACATCCAGAAGCATTAGCTGCCTTTGTTTTAGATAAAAAAGCAGATGTTGGTTTAGCTTTT
GATGGCGATGGCGACCGTGTTATTGCAATAGACGAAATTGGTCAAATTGTCGATGGAGATAAAATTATGTTTATCTGCGC
GAAATATTTACGTGAACAAGGCTTATTAAATAACAACACAATTGTATCAACAGTTATGAGTAATCTAGGCTTCTATAAAG
GTTTGAAAGAGCTTGAGATTGAAGATGTACAAACTGCAGTGGGTGACCGTTATGTAGTAGAAGCTATGCGTGAAGGTAAT
TATAATCTTGGCGGAGAACAATCTGGTCATATTATTTTCTTAGATCATAATACAACTGGTGATGGACTTCTTTCAGGAAT
CCAATTAATCAACGTGATGAAAGCAACTGGGAAAAAATTATCTGAGCTTGCGGCTGAAATGAAAACATTCCCGCAAAAAC
TAGAAAACATCCGTGTAAGTGATAAAAACCATGTAACAGATAATCCGAAAGTAAGTAAAGTAATCGGTGAAGTAGAAGCT
GAAATGGCTGGTAATGGTCGAGTTCTTGTTCGCCCATCAGGTACAGAACCATTAGTAAGAGTGATGGTAGAAGCTGCTAC
GAAAGAAGAAACAGACGAATATTGTGAACGTATTTCAGCGGTTGTTCGTTCAGAAATGGCACTTAACGATTAA

Upstream 100 bases:

>100_bases
TTGAGATTAGCAAAGATAGAACCAGCATTTGACAAAGTAATGATGAAATGACAAACAAAAATCATTTAGATAATGAATGA
CTTAGAAGGAGAGTAATGAA

Downstream 100 bases:

>100_bases
AACAACAAACAAAAAATCCTGATGATAAACTTCATCAGGATTTTATTTCTTTTAATAGAATGATTTGATCTAAGCAAGCA
ATGCCGTTTTCGATAATTGT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MGKYFGTDGVRGVANSELTPELAFRLGRMGGYVLTRHVGEHPRVLVARDTRISGEMLESALIAGLVSVGIEVMRLGVIST
PGVAYLTKAQGASASVMISASHNPVDDNGIKFFGSDGFKLSDDQEEEIEQLLDTAEDTLPRPSGEGLGTVSDYFEGKQKY
IQYLKQTIENDFNGYHIALDCANGATSGLATHLFADLDADISSMGASPNGLNINDGVGSTHPEALAAFVLDKKADVGLAF
DGDGDRVIAIDEIGQIVDGDKIMFICAKYLREQGLLNNNTIVSTVMSNLGFYKGLKELEIEDVQTAVGDRYVVEAMREGN
YNLGGEQSGHIIFLDHNTTGDGLLSGIQLINVMKATGKKLSELAAEMKTFPQKLENIRVSDKNHVTDNPKVSKVIGEVEA
EMAGNGRVLVRPSGTEPLVRVMVEAATKEETDEYCERISAVVRSEMALND

Sequences:

>Translated_450_residues
MGKYFGTDGVRGVANSELTPELAFRLGRMGGYVLTRHVGEHPRVLVARDTRISGEMLESALIAGLVSVGIEVMRLGVIST
PGVAYLTKAQGASASVMISASHNPVDDNGIKFFGSDGFKLSDDQEEEIEQLLDTAEDTLPRPSGEGLGTVSDYFEGKQKY
IQYLKQTIENDFNGYHIALDCANGATSGLATHLFADLDADISSMGASPNGLNINDGVGSTHPEALAAFVLDKKADVGLAF
DGDGDRVIAIDEIGQIVDGDKIMFICAKYLREQGLLNNNTIVSTVMSNLGFYKGLKELEIEDVQTAVGDRYVVEAMREGN
YNLGGEQSGHIIFLDHNTTGDGLLSGIQLINVMKATGKKLSELAAEMKTFPQKLENIRVSDKNHVTDNPKVSKVIGEVEA
EMAGNGRVLVRPSGTEPLVRVMVEAATKEETDEYCERISAVVRSEMALND
>Mature_449_residues
GKYFGTDGVRGVANSELTPELAFRLGRMGGYVLTRHVGEHPRVLVARDTRISGEMLESALIAGLVSVGIEVMRLGVISTP
GVAYLTKAQGASASVMISASHNPVDDNGIKFFGSDGFKLSDDQEEEIEQLLDTAEDTLPRPSGEGLGTVSDYFEGKQKYI
QYLKQTIENDFNGYHIALDCANGATSGLATHLFADLDADISSMGASPNGLNINDGVGSTHPEALAAFVLDKKADVGLAFD
GDGDRVIAIDEIGQIVDGDKIMFICAKYLREQGLLNNNTIVSTVMSNLGFYKGLKELEIEDVQTAVGDRYVVEAMREGNY
NLGGEQSGHIIFLDHNTTGDGLLSGIQLINVMKATGKKLSELAAEMKTFPQKLENIRVSDKNHVTDNPKVSKVIGEVEAE
MAGNGRVLVRPSGTEPLVRVMVEAATKEETDEYCERISAVVRSEMALND

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1789566, Length=453, Percent_Identity=44.8123620309051, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1788361, Length=460, Percent_Identity=26.304347826087, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR018247
- InterPro:   IPR006352 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 48430; Mature: 48299

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00018 EF_HAND_1 ; PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYFGTDGVRGVANSELTPELAFRLGRMGGYVLTRHVGEHPRVLVARDTRISGEMLESA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEHHCCCCCCEEEEECCCCCHHHHHHH
LIAGLVSVGIEVMRLGVISTPGVAYLTKAQGASASVMISASHNPVDDNGIKFFGSDGFKL
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCC
SDDQEEEIEQLLDTAEDTLPRPSGEGLGTVSDYFEGKQKYIQYLKQTIENDFNGYHIALD
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
CANGATSGLATHLFADLDADISSMGASPNGLNINDGVGSTHPEALAAFVLDKKADVGLAF
CCCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEE
DGDGDRVIAIDEIGQIVDGDKIMFICAKYLREQGLLNNNTIVSTVMSNLGFYKGLKELEI
ECCCCEEEEHHHHCHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
EDVQTAVGDRYVVEAMREGNYNLGGEQSGHIIFLDHNTTGDGLLSGIQLINVMKATGKKL
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
SELAAEMKTFPQKLENIRVSDKNHVTDNPKVSKVIGEVEAEMAGNGRVLVRPSGTEPLVR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
VMVEAATKEETDEYCERISAVVRSEMALND
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKYFGTDGVRGVANSELTPELAFRLGRMGGYVLTRHVGEHPRVLVARDTRISGEMLESA
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEHHCCCCCCEEEEECCCCCHHHHHHH
LIAGLVSVGIEVMRLGVISTPGVAYLTKAQGASASVMISASHNPVDDNGIKFFGSDGFKL
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCC
SDDQEEEIEQLLDTAEDTLPRPSGEGLGTVSDYFEGKQKYIQYLKQTIENDFNGYHIALD
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
CANGATSGLATHLFADLDADISSMGASPNGLNINDGVGSTHPEALAAFVLDKKADVGLAF
CCCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEE
DGDGDRVIAIDEIGQIVDGDKIMFICAKYLREQGLLNNNTIVSTVMSNLGFYKGLKELEI
ECCCCEEEEHHHHCHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
EDVQTAVGDRYVVEAMREGNYNLGGEQSGHIIFLDHNTTGDGLLSGIQLINVMKATGKKL
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
SELAAEMKTFPQKLENIRVSDKNHVTDNPKVSKVIGEVEAEMAGNGRVLVRPSGTEPLVR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
VMVEAATKEETDEYCERISAVVRSEMALND
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]