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The map label for this gene is rex

Identifier: 226224678

GI number: 226224678

Start: 2150413

End: 2151060

Strand: Reverse

Name: rex

Synonym: Lm4b_02093

Alternate gene names: 226224678

Gene position: 2151060-2150413 (Counterclockwise)

Preceding gene: 226224681

Following gene: 226224675

Centisome position: 73.85

GC content: 37.35

Gene sequence:

>648_bases
ATGATGGAGGAAACAACTAAAATTCCACAAGCGACAGCAAAACGCTTACCATTATATCATCGTTACTTGAAATACTTAGA
TGAGTCAGGTAAGGAACGAGTATCATCTGCGGAATTAAGTGAAGCGGTGAAAGTTGATTCAGCGACTATTCGACGTGATT
TTTCGTACTTTGGCGCATTAGGTAAGAAAGGATACGGGTATAACGTTTCTTACATACTCGACTTTTTCAGCAAAACACTT
AGCCAGGACAAACAGACAAATGTTGCACTAATCGGTGTAGGTAACCTAGGTACAGCATTATTACATTATAATTTCATGAA
AAATAATAATATCAAAATCGTTGCTGCATTTGATGTGGATCCAGCGAAAGTAGGTAGTGTTCAACAAGATATTCCAATCT
ATCATTTGAATGATATGGAAGAAATTGTTCGTGAAAACGGTGTGGAAGTAGTTATTCTGACAGTTCCAGCTGACGAAGCG
CAAGTAACGGTTGATCGTTTAATTGAAGCAGATGTAAAAGGTATTCTAAACTTTACACCAGCTCGTATCAGTGTTCCGAA
ACAAGTTCGTGTGCACCATATCGATCTTACAACGGAATTACAAACGTTAATCTATTTCCTGGAAAATTATCCAGCGAAAA
CAGAATAA

Upstream 100 bases:

>100_bases
TTGTGAAATGTTTATAGTATATAAGCAAGCATGTGAAAGGAAGTACAGTTCACAATAGCTTCAACTTCAGAAAAAATTAA
AAGAAGAAGGGACAGAAGGC

Downstream 100 bases:

>100_bases
AAAAACCTGTAGAAGGTAAGCAACACTTACTTTCTACAGGTTTTTTTTACGTCTTTTAAGTCCAGTGATAATCAGACCGA
TGCCAATACCAAAATCCATT

Product: redox-sensing transcriptional repressor Rex

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MMEETTKIPQATAKRLPLYHRYLKYLDESGKERVSSAELSEAVKVDSATIRRDFSYFGALGKKGYGYNVSYILDFFSKTL
SQDKQTNVALIGVGNLGTALLHYNFMKNNNIKIVAAFDVDPAKVGSVQQDIPIYHLNDMEEIVRENGVEVVILTVPADEA
QVTVDRLIEADVKGILNFTPARISVPKQVRVHHIDLTTELQTLIYFLENYPAKTE

Sequences:

>Translated_215_residues
MMEETTKIPQATAKRLPLYHRYLKYLDESGKERVSSAELSEAVKVDSATIRRDFSYFGALGKKGYGYNVSYILDFFSKTL
SQDKQTNVALIGVGNLGTALLHYNFMKNNNIKIVAAFDVDPAKVGSVQQDIPIYHLNDMEEIVRENGVEVVILTVPADEA
QVTVDRLIEADVKGILNFTPARISVPKQVRVHHIDLTTELQTLIYFLENYPAKTE
>Mature_215_residues
MMEETTKIPQATAKRLPLYHRYLKYLDESGKERVSSAELSEAVKVDSATIRRDFSYFGALGKKGYGYNVSYILDFFSKTL
SQDKQTNVALIGVGNLGTALLHYNFMKNNNIKIVAAFDVDPAKVGSVQQDIPIYHLNDMEEIVRENGVEVVILTVPADEA
QVTVDRLIEADVKGILNFTPARISVPKQVRVHHIDLTTELQTLIYFLENYPAKTE

Specific function: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state

COG id: COG2344

COG function: function code R; AT-rich DNA-binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory rex family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): REX_LISIN (P60383)

Other databases:

- EMBL:   AL596171
- PIR:   AG1704
- RefSeq:   NP_471511.1
- ProteinModelPortal:   P60383
- SMR:   P60383
- GeneID:   1130909
- GenomeReviews:   AL592022_GR
- KEGG:   lin:lin2178
- GenoList:   LIN2178
- HOGENOM:   HBG482264
- OMA:   TRGVGYD
- ProtClustDB:   PRK05472
- BioCyc:   LINN272626:LIN2178-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_01131
- InterPro:   IPR003781
- InterPro:   IPR016040
- InterPro:   IPR009718
- InterPro:   IPR022876
- InterPro:   IPR011991
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00881

Pfam domain/function: PF02629 CoA_binding; PF06971 Put_DNA-bind_N

EC number: NA

Molecular weight: Translated: 24200; Mature: 24200

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEETTKIPQATAKRLPLYHRYLKYLDESGKERVSSAELSEAVKVDSATIRRDFSYFGAL
CCCCHHCCCHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
GKKGYGYNVSYILDFFSKTLSQDKQTNVALIGVGNLGTALLHYNFMKNNNIKIVAAFDVD
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHEEEEEECCCEEEEEEECCC
PAKVGSVQQDIPIYHLNDMEEIVRENGVEVVILTVPADEAQVTVDRLIEADVKGILNFTP
HHHCCCCCCCCCEEEECCHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
ARISVPKQVRVHHIDLTTELQTLIYFLENYPAKTE
CEECCCCEEEEEEEEHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMEETTKIPQATAKRLPLYHRYLKYLDESGKERVSSAELSEAVKVDSATIRRDFSYFGAL
CCCCHHCCCHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
GKKGYGYNVSYILDFFSKTLSQDKQTNVALIGVGNLGTALLHYNFMKNNNIKIVAAFDVD
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHEEEEEECCCEEEEEEECCC
PAKVGSVQQDIPIYHLNDMEEIVRENGVEVVILTVPADEAQVTVDRLIEADVKGILNFTP
HHHCCCCCCCCCEEEECCHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
ARISVPKQVRVHHIDLTTELQTLIYFLENYPAKTE
CEECCCCEEEEEEEEHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669