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The map label for this gene is groES

Identifier: 226224675

GI number: 226224675

Start: 2148975

End: 2149259

Strand: Reverse

Name: groES

Synonym: Lm4b_02090

Alternate gene names: 226224675

Gene position: 2149259-2148975 (Counterclockwise)

Preceding gene: 226224678

Following gene: 226224674

Centisome position: 73.79

GC content: 39.3

Gene sequence:

>285_bases
TTGTTAAAACCATTAGGAGATCGTGTTGTAATTGAAGTACTTGAAGCAGAGGAAAAAACAGCGAGTGGGATTGTATTACC
AGACTCTGCCAAAGAAAAACCGCAATCAGGGAAAATTGTTGCAGTCGGTTCAGGTCGTGTGCTAGATAATGGCACAAAAG
AACCACTTGAAGTTGCAGAAGGTGACACGGTTATCTTCGCAAAATACTCTGGAACAGAAGTGACGTATGAAGGAACTGAC
TATCTGATTTTACGTGAAAGTGACATTTTAGCAATTACTAAATAA

Upstream 100 bases:

>100_bases
CATTTTTTATTCAGTTTGGTATCATAATAACTGTATTAGCACTCTAATGTGCCGAGTGCTAAAATGAAAAATGTAATTAT
ATCAGAGGAGGTCATTTACA

Downstream 100 bases:

>100_bases
TTAAAAAAAGAAATAATCGGAGGGAAATATAAAATGGCAAAAGATATTAAATTTAGTGAAGATGCTCGTCGTGCCATGTT
ACGTGGTGTCGACCAATTAG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MLKPLGDRVVIEVLEAEEKTASGIVLPDSAKEKPQSGKIVAVGSGRVLDNGTKEPLEVAEGDTVIFAKYSGTEVTYEGTD
YLILRESDILAITK

Sequences:

>Translated_94_residues
MLKPLGDRVVIEVLEAEEKTASGIVLPDSAKEKPQSGKIVAVGSGRVLDNGTKEPLEVAEGDTVIFAKYSGTEVTYEGTD
YLILRESDILAITK
>Mature_94_residues
MLKPLGDRVVIEVLEAEEKTASGIVLPDSAKEKPQSGKIVAVGSGRVLDNGTKEPLEVAEGDTVIFAKYSGTEVTYEGTD
YLILRESDILAITK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Escherichia coli, GI1790585, Length=94, Percent_Identity=45.7446808510638, Blast_Score=77, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555568, Length=91, Percent_Identity=40.6593406593407, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6324594, Length=89, Percent_Identity=39.3258426966292, Blast_Score=62, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356029, Length=91, Percent_Identity=43.956043956044, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10065; Mature: 10065

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPLGDRVVIEVLEAEEKTASGIVLPDSAKEKPQSGKIVAVGSGRVLDNGTKEPLEVAE
CCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEECCEEECCCCCCCCEECC
GDTVIFAKYSGTEVTYEGTDYLILRESDILAITK
CCEEEEEEECCCEEEECCCCEEEEECCCEEEEEC
>Mature Secondary Structure
MLKPLGDRVVIEVLEAEEKTASGIVLPDSAKEKPQSGKIVAVGSGRVLDNGTKEPLEVAE
CCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEECCEEECCCCCCCCEECC
GDTVIFAKYSGTEVTYEGTDYLILRESDILAITK
CCEEEEEEECCCEEEECCCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]