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The map label for this gene is coaD

Identifier: 226224658

GI number: 226224658

Start: 2135389

End: 2135871

Strand: Reverse

Name: coaD

Synonym: Lm4b_02073

Alternate gene names: 226224658

Gene position: 2135871-2135389 (Counterclockwise)

Preceding gene: 226224659

Following gene: 226224657

Centisome position: 73.33

GC content: 40.79

Gene sequence:

>483_bases
ATGGGTGACAAAATTGCCGTTATTCCCGGGACATTTGATCCGATTACGAATGGGCACTTAGACATTATTGAACGGGCAGC
GAAGATTTTTGATGTGCTGTATGTTTCCGTTTTAAACAACTCATCCAAAAAACCACTTTTCACGATAGAAGAGCGGATGG
AAATGATTAGACAAGTAACCGCACATTTGCCAAATGTTCAAGTGGAAAGTGCGAGCGGATTGACTGTTGATTATGCTGCT
ACGCGCGGGGCTACTGCAATTGTCAGAGGGCTTCGAGCGGTGAGTGATTTTGAATACGAGATGCAAATTGCTTCGATGAA
CCGAACGCTCAATGCGGAAATCGAAACATTTTTCATTATGACTAATACGAAATATTCTTTTTTAAGTTCCAGTATGGTAA
AAGAAGTGGCGCAGTATCAAGGTGATATCAGCGAACTTGTTCCTGAAATAGTGAACGAACAAGTACAAGCAAAATTTAAG
TAA

Upstream 100 bases:

>100_bases
AAGCAATCATGCCAGATACAATCGGTAAATTCGAGAAAATCAAATCAGTTTCTTATGGAATTACTGTTTTATCTATATTT
GAATTTCAGGAGGCGTAGAA

Downstream 100 bases:

>100_bases
GTGGGAGATGGACAGAAAATGCGTAAAGAGTGGAAAAAAATAACGGCGATAGTGCTGTTAATTATTATTATAGCGGGCTT
TTTTATTCCAGTTCCGTATT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MGDKIAVIPGTFDPITNGHLDIIERAAKIFDVLYVSVLNNSSKKPLFTIEERMEMIRQVTAHLPNVQVESASGLTVDYAA
TRGATAIVRGLRAVSDFEYEMQIASMNRTLNAEIETFFIMTNTKYSFLSSSMVKEVAQYQGDISELVPEIVNEQVQAKFK

Sequences:

>Translated_160_residues
MGDKIAVIPGTFDPITNGHLDIIERAAKIFDVLYVSVLNNSSKKPLFTIEERMEMIRQVTAHLPNVQVESASGLTVDYAA
TRGATAIVRGLRAVSDFEYEMQIASMNRTLNAEIETFFIMTNTKYSFLSSSMVKEVAQYQGDISELVPEIVNEQVQAKFK
>Mature_159_residues
GDKIAVIPGTFDPITNGHLDIIERAAKIFDVLYVSVLNNSSKKPLFTIEERMEMIRQVTAHLPNVQVESASGLTVDYAAT
RGATAIVRGLRAVSDFEYEMQIASMNRTLNAEIETFFIMTNTKYSFLSSSMVKEVAQYQGDISELVPEIVNEQVQAKFK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=51.9230769230769, Blast_Score=182, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 17857; Mature: 17726

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDKIAVIPGTFDPITNGHLDIIERAAKIFDVLYVSVLNNSSKKPLFTIEERMEMIRQVT
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHH
AHLPNVQVESASGLTVDYAATRGATAIVRGLRAVSDFEYEMQIASMNRTLNAEIETFFIM
HHCCCCEEECCCCCEEEHHHHCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEEEE
TNTKYSFLSSSMVKEVAQYQGDISELVPEIVNEQVQAKFK
ECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GDKIAVIPGTFDPITNGHLDIIERAAKIFDVLYVSVLNNSSKKPLFTIEERMEMIRQVT
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHH
AHLPNVQVESASGLTVDYAATRGATAIVRGLRAVSDFEYEMQIASMNRTLNAEIETFFIM
HHCCCCEEECCCCCEEEHHHHCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEEEE
TNTKYSFLSSSMVKEVAQYQGDISELVPEIVNEQVQAKFK
ECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]