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The map label for this gene is glmS [H]

Identifier: 226224597

GI number: 226224597

Start: 2060947

End: 2062011

Strand: Reverse

Name: glmS [H]

Synonym: Lm4b_02011

Alternate gene names: 226224597

Gene position: 2062011-2060947 (Counterclockwise)

Preceding gene: 226224598

Following gene: 226224596

Centisome position: 70.79

GC content: 39.53

Gene sequence:

>1065_bases
ATGAAAAACATGGATTATTATATCCGGTCGGAACAAAGTGTTTATGAAAATATCATCCGAAGTCGAAAAGATCTTTTACA
AAAGGTCATTCAAATGGAGAAAGTGGACTATCAAGCAATTGTTATTTTTGCAACAGGTTCTAGTTCTAATGCGGCATTTG
CAGCGCAGTTATATATGTCGGATAAACTCGCTATTCCCGTATATGTGGAAGAACCGTCTACTGCAGGAAATTACATGCTT
CACTTAAACAAAAACACCTTATACATCGCTATATCACAAGGTGGGCACAGTTATTCCACTATTCATCTCGTAAAAGAAAT
TGAGCGTCAAGGTGGCATTGTTTTCACTTTAACGAGCGACTTAACAAGCCCGATTGCGAAAGAAAGTACGCGGGCAATTG
ATCTCGGGATGGGGATAGAAGAGATGCCATATGTCACGCTTGGTTATAGCGCAACCATTCTCATGTTGAATTTAATGGCG
CTTGAGCTAGCCCTTTTACAAGAGAAAATGTTGGAAGAAGAATATCAAGCGGAAATTGCAGAATTGAAAAAAATTACCGC
TAATTTACCAAAAGTGGTAGAGAAATCAGCAGCTTGGGTAGACGCGCATACACAGGAATTGATGGAAGCGGAACGAGTTT
TCTTCATAGGATACGGCGCTGCTTATGGTGTAGCGCGCGAAGGAGAAACAAAAGTAACAGAAACCATCCGGATTACAGCT
TTTGGTAAGGAGTTAGAAGAATATATGCACGGACCTTATATAGGTTTATCCGAGCAAGACTATATTATCTTCCTTGAACC
TCAAGGCTTACTAGAAGACCGCGCAGAAAAATTAAAACAATTTTTACAAGGCCATGTAAAGAAAATCCGAACATTTTATG
CGGATGCAGGCGGGGAAAAGGCAGATGATTTATTACTCGGTGTGCGGGCAGCAGAACTTCTGACACCGCTGTTTATGACT
ATTCCGGTTCATTTATTATCCTTTGAAATTTCCAAGAAAAAAGGAATTAATTTAGAAGTATCCGCTTTTCCGGAGTTTGA
CCAAATAACGAAATCCAAAATTTAA

Upstream 100 bases:

>100_bases
AGATAAAAAAGGACTAAAAGCACATTGGATTCTTTTATTAATCGCAGGAATTGGAATTTTAGGAGCGTTCACAGGTTTAT
TAAAATAAGTAGGTGAAAAA

Downstream 100 bases:

>100_bases
TCAAAGAAAGTAGGAATGAATAGTGCTAAAATTTGATGAACAAAAAGTGAGAGAAAACATGGAAGGAGCGCTAAAATTAC
GCCCGCAAATTAATGAAGTA

Product: glucosamine-fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKNMDYYIRSEQSVYENIIRSRKDLLQKVIQMEKVDYQAIVIFATGSSSNAAFAAQLYMSDKLAIPVYVEEPSTAGNYML
HLNKNTLYIAISQGGHSYSTIHLVKEIERQGGIVFTLTSDLTSPIAKESTRAIDLGMGIEEMPYVTLGYSATILMLNLMA
LELALLQEKMLEEEYQAEIAELKKITANLPKVVEKSAAWVDAHTQELMEAERVFFIGYGAAYGVAREGETKVTETIRITA
FGKELEEYMHGPYIGLSEQDYIIFLEPQGLLEDRAEKLKQFLQGHVKKIRTFYADAGGEKADDLLLGVRAAELLTPLFMT
IPVHLLSFEISKKKGINLEVSAFPEFDQITKSKI

Sequences:

>Translated_354_residues
MKNMDYYIRSEQSVYENIIRSRKDLLQKVIQMEKVDYQAIVIFATGSSSNAAFAAQLYMSDKLAIPVYVEEPSTAGNYML
HLNKNTLYIAISQGGHSYSTIHLVKEIERQGGIVFTLTSDLTSPIAKESTRAIDLGMGIEEMPYVTLGYSATILMLNLMA
LELALLQEKMLEEEYQAEIAELKKITANLPKVVEKSAAWVDAHTQELMEAERVFFIGYGAAYGVAREGETKVTETIRITA
FGKELEEYMHGPYIGLSEQDYIIFLEPQGLLEDRAEKLKQFLQGHVKKIRTFYADAGGEKADDLLLGVRAAELLTPLFMT
IPVHLLSFEISKKKGINLEVSAFPEFDQITKSKI
>Mature_354_residues
MKNMDYYIRSEQSVYENIIRSRKDLLQKVIQMEKVDYQAIVIFATGSSSNAAFAAQLYMSDKLAIPVYVEEPSTAGNYML
HLNKNTLYIAISQGGHSYSTIHLVKEIERQGGIVFTLTSDLTSPIAKESTRAIDLGMGIEEMPYVTLGYSATILMLNLMA
LELALLQEKMLEEEYQAEIAELKKITANLPKVVEKSAAWVDAHTQELMEAERVFFIGYGAAYGVAREGETKVTETIRITA
FGKELEEYMHGPYIGLSEQDYIIFLEPQGLLEDRAEKLKQFLQGHVKKIRTFYADAGGEKADDLLLGVRAAELLTPLFMT
IPVHLLSFEISKKKGINLEVSAFPEFDQITKSKI

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Escherichia coli, GI1790167, Length=318, Percent_Identity=23.5849056603774, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17539970, Length=314, Percent_Identity=22.9299363057325, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 39779; Mature: 39779

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNMDYYIRSEQSVYENIIRSRKDLLQKVIQMEKVDYQAIVIFATGSSSNAAFAAQLYMS
CCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEEEEC
DKLAIPVYVEEPSTAGNYMLHLNKNTLYIAISQGGHSYSTIHLVKEIERQGGIVFTLTSD
CCEEEEEEEECCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCH
LTSPIAKESTRAIDLGMGIEEMPYVTLGYSATILMLNLMALELALLQEKMLEEEYQAEIA
HCCHHHHHCCCEEEECCCHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKKITANLPKVVEKSAAWVDAHTQELMEAERVFFIGYGAAYGVAREGETKVTETIRITA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECHHHCCCCCCCCCEEEEEEEEE
FGKELEEYMHGPYIGLSEQDYIIFLEPQGLLEDRAEKLKQFLQGHVKKIRTFYADAGGEK
EHHHHHHHHCCCEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ADDLLLGVRAAELLTPLFMTIPVHLLSFEISKKKGINLEVSAFPEFDQITKSKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCHHHHHHCCC
>Mature Secondary Structure
MKNMDYYIRSEQSVYENIIRSRKDLLQKVIQMEKVDYQAIVIFATGSSSNAAFAAQLYMS
CCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEEEEC
DKLAIPVYVEEPSTAGNYMLHLNKNTLYIAISQGGHSYSTIHLVKEIERQGGIVFTLTSD
CCEEEEEEEECCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCH
LTSPIAKESTRAIDLGMGIEEMPYVTLGYSATILMLNLMALELALLQEKMLEEEYQAEIA
HCCHHHHHCCCEEEECCCHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKKITANLPKVVEKSAAWVDAHTQELMEAERVFFIGYGAAYGVAREGETKVTETIRITA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECHHHCCCCCCCCCEEEEEEEEE
FGKELEEYMHGPYIGLSEQDYIIFLEPQGLLEDRAEKLKQFLQGHVKKIRTFYADAGGEK
EHHHHHHHHCCCEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ADDLLLGVRAAELLTPLFMTIPVHLLSFEISKKKGINLEVSAFPEFDQITKSKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]