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The map label for this gene is dra

Identifier: 226224593

GI number: 226224593

Start: 2057717

End: 2058388

Strand: Reverse

Name: dra

Synonym: Lm4b_02007

Alternate gene names: 226224593

Gene position: 2058388-2057717 (Counterclockwise)

Preceding gene: 226224594

Following gene: 226224592

Centisome position: 70.67

GC content: 42.26

Gene sequence:

>672_bases
ATGACAATTGCCAAAATGATCGATCACACTGCTTTAAAACCAGACACAACGAAAGAACAAATTTTAACACTAACAAAAGA
AGCGAGAGAATACGGTTTTGCTTCCGTATGCGTAAATCCAACTTGGGTAAAACTATCCGCTGAACAACTTGCTGGAGCAG
AATCCGTAGTATGTACTGTTATCGGTTTCCCACTAGGAGCGAATACCCCTGAAGTAAAAGCATTTGAAGTAAAAGATGCT
ATCCAAAACGGTGCAAAAGAAGTGGATATGGTTATTAATATCGGCGCACTAAAAGACAAAGACGACGAACTAGTAGAACG
TGATATTCGCGCTGTAGTCGATGCTGCCAAAGGAAAAGCATTAGTAAAAGTAATTATCGAAACTTGCCTATTAACAGACG
AAGAAAAAGTTCGCGCATGTGAAATCGCTGTAAAAGCGGGAACAGACTTCGTTAAAACATCCACTGGATTCTCCACAGGT
GGCGCAACTGCCGAAGATATCGCCTTAATGCGTAAAACTGTAGGACCAAACATCGGCGTAAAAGCATCTGGTGGGGTTCG
TACGAAAGAAGACGTAGAAAAAATGATCGAAGCAGGCGCAACTCGTATTGGCGCAAGTGCAGGTGTCGCAATTGTTTCCG
GCGAAAAACCAGCCAAACCAGATAATTACTAA

Upstream 100 bases:

>100_bases
CCGCAAAACAACTACTTGAACAAAATTTCATCAATTAGTTTACAAATGTTCTGTAGTGCGATATGATGAAACCAAATCCA
ATTTTAAAGGAGTTTTTAAA

Downstream 100 bases:

>100_bases
TTTTGGATGAAACCCCTTTATTATTATTCTTAAATGTGGCAAAATAAGGAGAATAGATAATCTGACTGGGGGAGTTTAAA
TGGCTGCAACCATCCGCGAA

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTIAKMIDHTALKPDTTKEQILTLTKEAREYGFASVCVNPTWVKLSAEQLAGAESVVCTVIGFPLGANTPEVKAFEVKDA
IQNGAKEVDMVINIGALKDKDDELVERDIRAVVDAAKGKALVKVIIETCLLTDEEKVRACEIAVKAGTDFVKTSTGFSTG
GATAEDIALMRKTVGPNIGVKASGGVRTKEDVEKMIEAGATRIGASAGVAIVSGEKPAKPDNY

Sequences:

>Translated_223_residues
MTIAKMIDHTALKPDTTKEQILTLTKEAREYGFASVCVNPTWVKLSAEQLAGAESVVCTVIGFPLGANTPEVKAFEVKDA
IQNGAKEVDMVINIGALKDKDDELVERDIRAVVDAAKGKALVKVIIETCLLTDEEKVRACEIAVKAGTDFVKTSTGFSTG
GATAEDIALMRKTVGPNIGVKASGGVRTKEDVEKMIEAGATRIGASAGVAIVSGEKPAKPDNY
>Mature_222_residues
TIAKMIDHTALKPDTTKEQILTLTKEAREYGFASVCVNPTWVKLSAEQLAGAESVVCTVIGFPLGANTPEVKAFEVKDAI
QNGAKEVDMVINIGALKDKDDELVERDIRAVVDAAKGKALVKVIIETCLLTDEEKVRACEIAVKAGTDFVKTSTGFSTGG
ATAEDIALMRKTVGPNIGVKASGGVRTKEDVEKMIEAGATRIGASAGVAIVSGEKPAKPDNY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI116063554, Length=169, Percent_Identity=34.9112426035503, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790841, Length=214, Percent_Identity=35.0467289719626, Blast_Score=94, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17533015, Length=235, Percent_Identity=28.5106382978723, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.4 [H]

Molecular weight: Translated: 23509; Mature: 23378

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAKMIDHTALKPDTTKEQILTLTKEAREYGFASVCVNPTWVKLSAEQLAGAESVVCTV
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCEEEEEEHHHHCCCHHEEEEE
IGFPLGANTPEVKAFEVKDAIQNGAKEVDMVINIGALKDKDDELVERDIRAVVDAAKGKA
EECCCCCCCCCCEEEHHHHHHHCCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHH
LVKVIIETCLLTDEEKVRACEIAVKAGTDFVKTSTGFSTGGATAEDIALMRKTVGPNIGV
HHHHHHHHHHCCCHHHHHHEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCE
KASGGVRTKEDVEKMIEAGATRIGASAGVAIVSGEKPAKPDNY
ECCCCCCCHHHHHHHHHHCCHHCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TIAKMIDHTALKPDTTKEQILTLTKEAREYGFASVCVNPTWVKLSAEQLAGAESVVCTV
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCEEEEEEHHHHCCCHHEEEEE
IGFPLGANTPEVKAFEVKDAIQNGAKEVDMVINIGALKDKDDELVERDIRAVVDAAKGKA
EECCCCCCCCCCEEEHHHHHHHCCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHH
LVKVIIETCLLTDEEKVRACEIAVKAGTDFVKTSTGFSTGGATAEDIALMRKTVGPNIGV
HHHHHHHHHHCCCHHHHHHEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCE
KASGGVRTKEDVEKMIEAGATRIGASAGVAIVSGEKPAKPDNY
ECCCCCCCHHHHHHHHHHCCHHCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]