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The map label for this gene is ykhA [H]

Identifier: 226224551

GI number: 226224551

Start: 2014901

End: 2015419

Strand: Reverse

Name: ykhA [H]

Synonym: Lm4b_01965

Alternate gene names: 226224551

Gene position: 2015419-2014901 (Counterclockwise)

Preceding gene: 226224552

Following gene: 226224550

Centisome position: 69.19

GC content: 38.34

Gene sequence:

>519_bases
ATGGAAAAAAGACAAACAAAATTTTGCAAAGAATCACTAGTAATTAAAACAAGCCGGGTTTTCCCGTCGGACACGAATAA
TCATAATACCCTTTTTGGTGGTAGATTGATGACTTATATTGATGATACGGCTTCTATCAGTGCCTCTCGTCATTGTCGTA
CGGAAATTGTCACTGCATCGACAGACTCAGTGGATTTCTTAAAACCGATTAAAAATGATCACTCTGTTTGCTTAGAGTCT
TATGTAGCTTCAACGGGCAGAAGTTCAATGGAAATCTTCGTTAAAATTATTGCGGAGAATTTGAAAACAGGAGAACGTTA
CTTAGCGGCGACATCCTTTTTAACATTTGTAGCGTTGGATGCAGATGGTAAAACTGTAGAAGTGCCACTCGTTAAACCAG
AAACAGAAGAACAAAAAAGAATCCACGCGGGTGCTGAGGCAAGAAGCATTGCTCGTAAAATTCGTTTAAAAGAAAACCAA
TCATTAGCGGAATCATTATCAACAGATATTCCATGGTGA

Upstream 100 bases:

>100_bases
AGAAGCACATAATGGGAAAATTTCGGTTGAAAGCGAATTAGGTAAAGGATCTGATTTTATTATCACTTTGCCTCTCTATA
AATAGATTGGAGCGAAAAAC

Downstream 100 bases:

>100_bases
ATTAATAAAAACTAGCTAAGCAGCTAGTTTTTATTTAATTTAGATAGAAAGCGCTTACGTGAAAAAATATACAAAAGTGC
TTGCCAAAAATTTTTTTCAT

Product: acyl-CoA hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MEKRQTKFCKESLVIKTSRVFPSDTNNHNTLFGGRLMTYIDDTASISASRHCRTEIVTASTDSVDFLKPIKNDHSVCLES
YVASTGRSSMEIFVKIIAENLKTGERYLAATSFLTFVALDADGKTVEVPLVKPETEEQKRIHAGAEARSIARKIRLKENQ
SLAESLSTDIPW

Sequences:

>Translated_172_residues
MEKRQTKFCKESLVIKTSRVFPSDTNNHNTLFGGRLMTYIDDTASISASRHCRTEIVTASTDSVDFLKPIKNDHSVCLES
YVASTGRSSMEIFVKIIAENLKTGERYLAATSFLTFVALDADGKTVEVPLVKPETEEQKRIHAGAEARSIARKIRLKENQ
SLAESLSTDIPW
>Mature_172_residues
MEKRQTKFCKESLVIKTSRVFPSDTNNHNTLFGGRLMTYIDDTASISASRHCRTEIVTASTDSVDFLKPIKNDHSVCLES
YVASTGRSSMEIFVKIIAENLKTGERYLAATSFLTFVALDADGKTVEVPLVKPETEEQKRIHAGAEARSIARKIRLKENQ
SLAESLSTDIPW

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI32528286, Length=138, Percent_Identity=35.5072463768116, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI32528284, Length=138, Percent_Identity=35.5072463768116, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI32528282, Length=138, Percent_Identity=35.5072463768116, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI75709208, Length=138, Percent_Identity=35.5072463768116, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI22165355, Length=154, Percent_Identity=29.2207792207792, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI22165400, Length=154, Percent_Identity=29.2207792207792, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI18640736, Length=149, Percent_Identity=27.5167785234899, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1787506, Length=122, Percent_Identity=31.1475409836066, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 19200; Mature: 19200

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRQTKFCKESLVIKTSRVFPSDTNNHNTLFGGRLMTYIDDTASISASRHCRTEIVTAS
CCCHHHHHHHHHHEEEECCCCCCCCCCCCEEECCEEEEEECCCHHCCCCCCCCEEEEECC
TDSVDFLKPIKNDHSVCLESYVASTGRSSMEIFVKIIAENLKTGERYLAATSFLTFVALD
CCCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEEC
ADGKTVEVPLVKPETEEQKRIHAGAEARSIARKIRLKENQSLAESLSTDIPW
CCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MEKRQTKFCKESLVIKTSRVFPSDTNNHNTLFGGRLMTYIDDTASISASRHCRTEIVTAS
CCCHHHHHHHHHHEEEECCCCCCCCCCCCEEECCEEEEEECCCHHCCCCCCCCEEEEECC
TDSVDFLKPIKNDHSVCLESYVASTGRSSMEIFVKIIAENLKTGERYLAATSFLTFVALD
CCCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEEC
ADGKTVEVPLVKPETEEQKRIHAGAEARSIARKIRLKENQSLAESLSTDIPW
CCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377; 10568751 [H]