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The map label for this gene is cmk

Identifier: 226224543

GI number: 226224543

Start: 2001949

End: 2002623

Strand: Reverse

Name: cmk

Synonym: Lm4b_01956

Alternate gene names: 226224543

Gene position: 2002623-2001949 (Counterclockwise)

Preceding gene: 226224544

Following gene: 226224542

Centisome position: 68.76

GC content: 38.96

Gene sequence:

>675_bases
ATGACTAAAAAGATATGTATCGCGATTGATGGACCGGCTGCGGCTGGGAAAAGCACGGTGGCGAAAATCGTTGCAAAAAA
ATTGCGCTTTGTCTATATTGATACGGGTGCCATGTATCGTGCAGTAACCTATATCGCTTTAAAAAATAACATCGCATATG
AAGACGAAAAAGCTATAGCTACTTTACTCCAAAAAACAGTTATTCGTTTTGAACCTGGCGAAGTACAACAAGTATTTGTA
GGTGAAGAAAATGTCACAGAAGTGATTCGTTCTTTAGAAGTGACCAATCATGTATCTATCGTTGCCGCACACCCGTCTAT
TCGTGAAGCACTCCAAGAACGTCAACAAGTTTTTGCTACAGAAGGCGGAATTGTAATGGATGGTCGTGATATCGGTACTG
CAGTTCTTCCTAACGCCGAACTAAAAATATTCTTACTAGCAAGCGTAGAAGAACGAGCGGAACGTCGCTATAAAGAGAAT
ATGGCGAAAGGTTTTGCTGGAGATTTAGGCCAACTCAAAAAAGAAATTGAAGAACGAGATCATTTAGATTATACAAGAAC
ACACTCCCCCTTAAAAAAAGCAGATGATGCCATTGAAGTAGATACAACATCAATGTCGATTGATGAAGTAGCCAATAAAA
TTCTTTCACTAGCAGAACTAAAAATCAATAATTAG

Upstream 100 bases:

>100_bases
AGATTACGATAGCAAAAAAGCACGGATGAAATTAATGGTACTTTTAGCATCACAAGAAGAAATTAATCAAACCAATTTCA
GATAAAAGGAGTTTTATTTT

Downstream 100 bases:

>100_bases
CAAAAAAGTGCTACATTTTCTTAACTAAATGGAAATGTAGCACTTTTTTAATTTAACCGTGAAAGGCTAAACAAACGAAG
CGATTTCACGCCCTGTAGGC

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTKKICIAIDGPAAAGKSTVAKIVAKKLRFVYIDTGAMYRAVTYIALKNNIAYEDEKAIATLLQKTVIRFEPGEVQQVFV
GEENVTEVIRSLEVTNHVSIVAAHPSIREALQERQQVFATEGGIVMDGRDIGTAVLPNAELKIFLLASVEERAERRYKEN
MAKGFAGDLGQLKKEIEERDHLDYTRTHSPLKKADDAIEVDTTSMSIDEVANKILSLAELKINN

Sequences:

>Translated_224_residues
MTKKICIAIDGPAAAGKSTVAKIVAKKLRFVYIDTGAMYRAVTYIALKNNIAYEDEKAIATLLQKTVIRFEPGEVQQVFV
GEENVTEVIRSLEVTNHVSIVAAHPSIREALQERQQVFATEGGIVMDGRDIGTAVLPNAELKIFLLASVEERAERRYKEN
MAKGFAGDLGQLKKEIEERDHLDYTRTHSPLKKADDAIEVDTTSMSIDEVANKILSLAELKINN
>Mature_223_residues
TKKICIAIDGPAAAGKSTVAKIVAKKLRFVYIDTGAMYRAVTYIALKNNIAYEDEKAIATLLQKTVIRFEPGEVQQVFVG
EENVTEVIRSLEVTNHVSIVAAHPSIREALQERQQVFATEGGIVMDGRDIGTAVLPNAELKIFLLASVEERAERRYKENM
AKGFAGDLGQLKKEIEERDHLDYTRTHSPLKKADDAIEVDTTSMSIDEVANKILSLAELKINN

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787139, Length=218, Percent_Identity=42.2018348623853, Blast_Score=161, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003136
- InterPro:   IPR011994 [H]

Pfam domain/function: PF02224 Cytidylate_kin [H]

EC number: =2.7.4.14 [H]

Molecular weight: Translated: 24803; Mature: 24672

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKICIAIDGPAAAGKSTVAKIVAKKLRFVYIDTGAMYRAVTYIALKNNIAYEDEKAIA
CCCEEEEEECCCCCCCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHEECCCCCCHHHHHH
TLLQKTVIRFEPGEVQQVFVGEENVTEVIRSLEVTNHVSIVAAHPSIREALQERQQVFAT
HHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHC
EGGIVMDGRDIGTAVLPNAELKIFLLASVEERAERRYKENMAKGFAGDLGQLKKEIEERD
CCCEEECCCCCCCEECCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
HLDYTRTHSPLKKADDAIEVDTTSMSIDEVANKILSLAELKINN
CCCHHHCCCCHHHCCCCEEECCCCCCHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
TKKICIAIDGPAAAGKSTVAKIVAKKLRFVYIDTGAMYRAVTYIALKNNIAYEDEKAIA
CCEEEEEECCCCCCCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHEECCCCCCHHHHHH
TLLQKTVIRFEPGEVQQVFVGEENVTEVIRSLEVTNHVSIVAAHPSIREALQERQQVFAT
HHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHC
EGGIVMDGRDIGTAVLPNAELKIFLLASVEERAERRYKENMAKGFAGDLGQLKKEIEERD
CCCEEECCCCCCCEECCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
HLDYTRTHSPLKKADDAIEVDTTSMSIDEVANKILSLAELKINN
CCCHHHCCCCHHHCCCCEEECCCCCCHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]