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The map label for this gene is gpsA

Identifier: 226224540

GI number: 226224540

Start: 1997952

End: 1998968

Strand: Reverse

Name: gpsA

Synonym: Lm4b_01953

Alternate gene names: 226224540

Gene position: 1998968-1997952 (Counterclockwise)

Preceding gene: 226224541

Following gene: 226224539

Centisome position: 68.63

GC content: 39.63

Gene sequence:

>1017_bases
ATGACACAGAAAAAAGTAGCTATTCTTGGCGCTGGAAGTTGGGGAACAGGTCTTGCACTTGTCCTAGCTGATAATAATCA
TCAACCAGTTATTTGGGGAAACTTAGATAAAATTGTGAATGAAATTAACGAATCGCACACGAATAGTCACTATTTGCCAG
ATATTATTTTACCAACTGAGGTAAAAGCGACATTGTCACTTGATGAAGCTATTGATGGTGCAGAAATTGTCGTAATTGCT
ATTCCAACAAATGCGATGCGAATCGTTTGTAAGCAGTTAAATGAAGCGCTAAAAGAACCAACCATTTTAGTGCATGTGAG
TAAAGGTATTGAACCAGAAACAAATCTTCGAATGTCCGAAGTGATTGAAGACGAAATAGATGCGTCCAAACGTAAAGCGC
TTGTTGTTCTTTCTGGACCAAGTCATGCGGAAGAAGTTGCGCTTCGTCATCCGACAACACTTTGTGCGAGCTGTAAAGAT
TTATCAGCTGCTGAAATTGTTCAAGATCGTTTCATCAATAATAATTTGCGTATTTATACGAATGATGATGTGATTGGTGC
AGAAATTGGTGGCGCGCTGAAAAATATTATCGCACTAGGTGCAGGAATTTCTGACGGCCTTGGTTATGGCGATAATGCTA
AAGCGGCACTAATGACTCGCGGGATGGCAGAAATCACTCGTCTCGGTGTTGCTGTTGGCTCTAATCCGCAAACATTTTAC
GGATTGACAGGTATTGGTGACTTAATCGTTACTTGTACTAGTGTGCATTCACGTAATTGGCGTGCTGGTAATATGCTAGG
TAAAGGCGAGAATTTAGATGAAGTATTAGAAAAAATGGGCATGGTCGTTGAAGGTGTTCGAACAGCTAAAGCAGTACATG
GTTGGGCGAAAAAACTAGATATTGATATGCCAATTACCGAATCGATTTACGCGATTTTATTCGAAAATAAAGATGCTCGC
GAAGCAGTTGATTTATTAATGGGTCGCGAAAAAAAGATCGAAAAAGAATCATTTTAA

Upstream 100 bases:

>100_bases
TTCTTAGAAAACCGGATTAGAGAGGCATTTCCGTTTGAGGGTACGCCAATTCGAGTAATTGCTCGTAAGCGTAAGTAAAG
TTTTCGGGAGGAAAAATATA

Downstream 100 bases:

>100_bases
TAGAAAGAGTCAGAATGGGCTATCCGCTTATTTTGGCTCTTTTTTTATGAAATATGCTAGAATGTAGCAGAAGAGCCAAA
TAATAAAAAGTAGGTGGATA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTQKKVAILGAGSWGTGLALVLADNNHQPVIWGNLDKIVNEINESHTNSHYLPDIILPTEVKATLSLDEAIDGAEIVVIA
IPTNAMRIVCKQLNEALKEPTILVHVSKGIEPETNLRMSEVIEDEIDASKRKALVVLSGPSHAEEVALRHPTTLCASCKD
LSAAEIVQDRFINNNLRIYTNDDVIGAEIGGALKNIIALGAGISDGLGYGDNAKAALMTRGMAEITRLGVAVGSNPQTFY
GLTGIGDLIVTCTSVHSRNWRAGNMLGKGENLDEVLEKMGMVVEGVRTAKAVHGWAKKLDIDMPITESIYAILFENKDAR
EAVDLLMGREKKIEKESF

Sequences:

>Translated_338_residues
MTQKKVAILGAGSWGTGLALVLADNNHQPVIWGNLDKIVNEINESHTNSHYLPDIILPTEVKATLSLDEAIDGAEIVVIA
IPTNAMRIVCKQLNEALKEPTILVHVSKGIEPETNLRMSEVIEDEIDASKRKALVVLSGPSHAEEVALRHPTTLCASCKD
LSAAEIVQDRFINNNLRIYTNDDVIGAEIGGALKNIIALGAGISDGLGYGDNAKAALMTRGMAEITRLGVAVGSNPQTFY
GLTGIGDLIVTCTSVHSRNWRAGNMLGKGENLDEVLEKMGMVVEGVRTAKAVHGWAKKLDIDMPITESIYAILFENKDAR
EAVDLLMGREKKIEKESF
>Mature_337_residues
TQKKVAILGAGSWGTGLALVLADNNHQPVIWGNLDKIVNEINESHTNSHYLPDIILPTEVKATLSLDEAIDGAEIVVIAI
PTNAMRIVCKQLNEALKEPTILVHVSKGIEPETNLRMSEVIEDEIDASKRKALVVLSGPSHAEEVALRHPTTLCASCKDL
SAAEIVQDRFINNNLRIYTNDDVIGAEIGGALKNIIALGAGISDGLGYGDNAKAALMTRGMAEITRLGVAVGSNPQTFYG
LTGIGDLIVTCTSVHSRNWRAGNMLGKGENLDEVLEKMGMVVEGVRTAKAVHGWAKKLDIDMPITESIYAILFENKDARE
AVDLLMGREKKIEKESF

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=348, Percent_Identity=30.7471264367816, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI24307999, Length=347, Percent_Identity=29.6829971181556, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1790037, Length=340, Percent_Identity=39.1176470588235, Blast_Score=266, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI32564399, Length=347, Percent_Identity=31.4121037463977, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32564403, Length=355, Percent_Identity=31.5492957746479, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI193210136, Length=355, Percent_Identity=31.5492957746479, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17507425, Length=350, Percent_Identity=30, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193210134, Length=347, Percent_Identity=28.5302593659942, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324513, Length=345, Percent_Identity=30.7246376811594, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6320181, Length=353, Percent_Identity=29.1784702549575, Blast_Score=132, Evalue=5e-32,
Organism=Drosophila melanogaster, GI17136202, Length=350, Percent_Identity=29.4285714285714, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136204, Length=342, Percent_Identity=30.1169590643275, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136200, Length=342, Percent_Identity=30.1169590643275, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI22026922, Length=357, Percent_Identity=26.6106442577031, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45551945, Length=288, Percent_Identity=28.8194444444444, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281362270, Length=288, Percent_Identity=28.8194444444444, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24648969, Length=236, Percent_Identity=29.6610169491525, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36499; Mature: 36368

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKKVAILGAGSWGTGLALVLADNNHQPVIWGNLDKIVNEINESHTNSHYLPDIILPTE
CCCCEEEEEECCCCCCCEEEEEECCCCCCEEECCHHHHHHHHHHHCCCCCCCCCEECCCC
VKATLSLDEAIDGAEIVVIAIPTNAMRIVCKQLNEALKEPTILVHVSKGIEPETNLRMSE
CEEEEEHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHH
VIEDEIDASKRKALVVLSGPSHAEEVALRHPTTLCASCKDLSAAEIVQDRFINNNLRIYT
HHHHHHCCCCCEEEEEEECCCCHHHHHHCCCHHHHHCCCCCCHHHHHHHHHCCCCEEEEE
NDDVIGAEIGGALKNIIALGAGISDGLGYGDNAKAALMTRGMAEITRLGVAVGSNPQTFY
CCCEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEE
GLTGIGDLIVTCTSVHSRNWRAGNMLGKGENLDEVLEKMGMVVEGVRTAKAVHGWAKKLD
ECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IDMPITESIYAILFENKDAREAVDLLMGREKKIEKESF
CCCCCHHHEEEEEECCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TQKKVAILGAGSWGTGLALVLADNNHQPVIWGNLDKIVNEINESHTNSHYLPDIILPTE
CCCEEEEEECCCCCCCEEEEEECCCCCCEEECCHHHHHHHHHHHCCCCCCCCCEECCCC
VKATLSLDEAIDGAEIVVIAIPTNAMRIVCKQLNEALKEPTILVHVSKGIEPETNLRMSE
CEEEEEHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHH
VIEDEIDASKRKALVVLSGPSHAEEVALRHPTTLCASCKDLSAAEIVQDRFINNNLRIYT
HHHHHHCCCCCEEEEEEECCCCHHHHHHCCCHHHHHCCCCCCHHHHHHHHHCCCCEEEEE
NDDVIGAEIGGALKNIIALGAGISDGLGYGDNAKAALMTRGMAEITRLGVAVGSNPQTFY
CCCEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEE
GLTGIGDLIVTCTSVHSRNWRAGNMLGKGENLDEVLEKMGMVVEGVRTAKAVHGWAKKLD
ECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IDMPITESIYAILFENKDAREAVDLLMGREKKIEKESF
CCCCCHHHEEEEEECCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]