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The map label for this gene is blaSE [H]

Identifier: 226224474

GI number: 226224474

Start: 1931161

End: 1932513

Strand: Reverse

Name: blaSE [H]

Synonym: Lm4b_01887

Alternate gene names: 226224474

Gene position: 1932513-1931161 (Counterclockwise)

Preceding gene: 226224475

Following gene: 226224473

Centisome position: 66.35

GC content: 36.07

Gene sequence:

>1353_bases
ATGAAAAAGCTTAGAATATTTACTTTGATGCTTGCTTTTGCTCTATTTTTATTAGGTGGAGGAATTGTTGCACAAGCAGC
AGAGGAAGCCCCAATCGATGAAAAGATAGTTGGGGAAACGGTAACAAATGACGGAGAAGAGTTTATAGTCGATGAGATTA
GTGATTTAGAAGATGTTAATTCAACAACGGGGACGTTAGATACATCTGATGAAGTTGAGGTTGATTTATCAGGATTAACT
ATTGAAAATGAGGAAGCCGTTCTAACCCCAGGTTTAAAAACGATTTTTGGCGGAGATGGTAGAAAACTTGTAACAAATAC
AACTCAATATCCATATTCAACGAGCGCTTACCTTGTAATGGAATTTCCAAATGGAAAAACTTATATAGGTAGTGGACAAT
TGATTGGTGAAGATTCTGTACTTACAGCCGCTCATTGTTTATATGGTAAAAAAGATGGTGGATGGGCAAAAAAAGTGACT
GTATATCCTGGATATAATGGCACGAAAGCTCCTTTTGGAACAGCAAAAGCAAGAAAAATGTATGTTCCAAAAGAATGGAC
AAAAAAAGAACCTTCTACAGAAGATTATGGTGTTATTAAATTAGATAAAAATATTGGGACAAAAACTGGAACAATGGGGT
TAACAACTAATACATCTGGTGCAATTACTATTAGTGGTTATCATGGTGACAAAAAAGGGAAATTGTACACTCAAACTGGA
AATATCTCTCAAGTCACTGCAAATAATGTTTTTTATAGATTAGATACAACAGGTGGTAGTAGTGGTAGTGGTGTTTATAA
TTCTAAAAAACAGATTTTAGCAGTAAACGCATATGAATATTTAAATGGTACCGGGGACAACTTTGGTACAAGAATAACAA
AAGAAAAACTAAATAATATTTATACTTGGGCGTTTGACAATAATCTTTCTGTAAGCAAACAAAAAGGGATAAATTACGAG
CTCCACGTCCAAAGTAAGGGATGGATGGGAAACGTTGCTAATAGTATGACTTCGGGCACAGTTGGCCTTGGCTTACGAGC
AGAAGCAATGAAAATTAGTTTATCAGGGATGCCGTATTCTGGAGATATTCAATATCGCTCACATGTACAAGGTAGTGGAT
GGCAAGGTTGGTTGAAAAATGGGGAAATTTCTGGAACTCGTGGACAGTCAAAACGTCTGGAAGCTTTCCAAGTAAAATTA
ACTGGAAATATGGCTAAAAATTATAGTGTGCAGTATAGAGCGCATGTCCAAAATAAAGGTTGGCAAAGTTGGGTTAAAGA
TGGAGCAACAGCAGGAACAACAGGAGAAAGTTTAAGAATAGAAGCTGTACAAATGCGACTAGTTGCAAAATAA

Upstream 100 bases:

>100_bases
TTGGGAAGTTTTAAACTAATTTAAGTTTCAACAATGCGATACAATCAAGTGATTTTTTGATATATTTATTTGCTAATAGA
CAAAAAAAGGAGATGCAACT

Downstream 100 bases:

>100_bases
ATTTAAAAGAATTTGGTGTGTAAAATGCCAAATTCTTTTTCTTTTACCAAATTGATTGAAAAAGTAGAGCTAGTATAGTA
GAATTGAAAAGCAAGCACTT

Product: Hypothetical protein containing ChW-repeats

Products: NA

Alternate protein names: Glutamate-specific endopeptidase; GSE [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MKKLRIFTLMLAFALFLLGGGIVAQAAEEAPIDEKIVGETVTNDGEEFIVDEISDLEDVNSTTGTLDTSDEVEVDLSGLT
IENEEAVLTPGLKTIFGGDGRKLVTNTTQYPYSTSAYLVMEFPNGKTYIGSGQLIGEDSVLTAAHCLYGKKDGGWAKKVT
VYPGYNGTKAPFGTAKARKMYVPKEWTKKEPSTEDYGVIKLDKNIGTKTGTMGLTTNTSGAITISGYHGDKKGKLYTQTG
NISQVTANNVFYRLDTTGGSSGSGVYNSKKQILAVNAYEYLNGTGDNFGTRITKEKLNNIYTWAFDNNLSVSKQKGINYE
LHVQSKGWMGNVANSMTSGTVGLGLRAEAMKISLSGMPYSGDIQYRSHVQGSGWQGWLKNGEISGTRGQSKRLEAFQVKL
TGNMAKNYSVQYRAHVQNKGWQSWVKDGATAGTTGESLRIEAVQMRLVAK

Sequences:

>Translated_450_residues
MKKLRIFTLMLAFALFLLGGGIVAQAAEEAPIDEKIVGETVTNDGEEFIVDEISDLEDVNSTTGTLDTSDEVEVDLSGLT
IENEEAVLTPGLKTIFGGDGRKLVTNTTQYPYSTSAYLVMEFPNGKTYIGSGQLIGEDSVLTAAHCLYGKKDGGWAKKVT
VYPGYNGTKAPFGTAKARKMYVPKEWTKKEPSTEDYGVIKLDKNIGTKTGTMGLTTNTSGAITISGYHGDKKGKLYTQTG
NISQVTANNVFYRLDTTGGSSGSGVYNSKKQILAVNAYEYLNGTGDNFGTRITKEKLNNIYTWAFDNNLSVSKQKGINYE
LHVQSKGWMGNVANSMTSGTVGLGLRAEAMKISLSGMPYSGDIQYRSHVQGSGWQGWLKNGEISGTRGQSKRLEAFQVKL
TGNMAKNYSVQYRAHVQNKGWQSWVKDGATAGTTGESLRIEAVQMRLVAK
>Mature_450_residues
MKKLRIFTLMLAFALFLLGGGIVAQAAEEAPIDEKIVGETVTNDGEEFIVDEISDLEDVNSTTGTLDTSDEVEVDLSGLT
IENEEAVLTPGLKTIFGGDGRKLVTNTTQYPYSTSAYLVMEFPNGKTYIGSGQLIGEDSVLTAAHCLYGKKDGGWAKKVT
VYPGYNGTKAPFGTAKARKMYVPKEWTKKEPSTEDYGVIKLDKNIGTKTGTMGLTTNTSGAITISGYHGDKKGKLYTQTG
NISQVTANNVFYRLDTTGGSSGSGVYNSKKQILAVNAYEYLNGTGDNFGTRITKEKLNNIYTWAFDNNLSVSKQKGINYE
LHVQSKGWMGNVANSMTSGTVGLGLRAEAMKISLSGMPYSGDIQYRSHVQGSGWQGWLKNGEISGTRGQSKRLEAFQVKL
TGNMAKNYSVQYRAHVQNKGWQSWVKDGATAGTTGESLRIEAVQMRLVAK

Specific function: Specific for hydrolysis of peptide bonds on the carboxyl side of acidic amino acid residues, with a strong preference for Glu [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003
- InterPro:   IPR000126
- InterPro:   IPR001254
- InterPro:   IPR008256 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: =3.4.21.19 [H]

Molecular weight: Translated: 48794; Mature: 48794

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS00134 TRYPSIN_HIS ; PS50240 TRYPSIN_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLRIFTLMLAFALFLLGGGIVAQAAEEAPIDEKIVGETVTNDGEEFIVDEISDLEDVN
CCCHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCHHHCCCHHCCCCCEEHHHHHHHHHHCC
STTGTLDTSDEVEVDLSGLTIENEEAVLTPGLKTIFGGDGRKLVTNTTQYPYSTSAYLVM
CCCCCCCCCCCEEEEEECEEECCCCEEECCCCCEEECCCCCEEEECCCCCCCCCCEEEEE
EFPNGKTYIGSGQLIGEDSVLTAAHCLYGKKDGGWAKKVTVYPGYNGTKAPFGTAKARKM
ECCCCCEEECCCCEECCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
YVPKEWTKKEPSTEDYGVIKLDKNIGTKTGTMGLTTNTSGAITISGYHGDKKGKLYTQTG
ECCCHHCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEECC
NISQVTANNVFYRLDTTGGSSGSGVYNSKKQILAVNAYEYLNGTGDNFGTRITKEKLNNI
CEEEEEECCEEEEEECCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCCCCCEEEHHHHCCE
YTWAFDNNLSVSKQKGINYELHVQSKGWMGNVANSMTSGTVGLGLRAEAMKISLSGMPYS
EEEEECCCCCCHHHCCCCEEEEECCCCCCCHHHHCCCCCCEECCEEEEEEEEEECCCCCC
GDIQYRSHVQGSGWQGWLKNGEISGTRGQSKRLEAFQVKLTGNMAKNYSVQYRAHVQNKG
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCC
WQSWVKDGATAGTTGESLRIEAVQMRLVAK
HHHHHHCCCCCCCCCCCEEEEEEEEEEECC
>Mature Secondary Structure
MKKLRIFTLMLAFALFLLGGGIVAQAAEEAPIDEKIVGETVTNDGEEFIVDEISDLEDVN
CCCHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCHHHCCCHHCCCCCEEHHHHHHHHHHCC
STTGTLDTSDEVEVDLSGLTIENEEAVLTPGLKTIFGGDGRKLVTNTTQYPYSTSAYLVM
CCCCCCCCCCCEEEEEECEEECCCCEEECCCCCEEECCCCCEEEECCCCCCCCCCEEEEE
EFPNGKTYIGSGQLIGEDSVLTAAHCLYGKKDGGWAKKVTVYPGYNGTKAPFGTAKARKM
ECCCCCEEECCCCEECCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
YVPKEWTKKEPSTEDYGVIKLDKNIGTKTGTMGLTTNTSGAITISGYHGDKKGKLYTQTG
ECCCHHCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEECC
NISQVTANNVFYRLDTTGGSSGSGVYNSKKQILAVNAYEYLNGTGDNFGTRITKEKLNNI
CEEEEEECCEEEEEECCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCCCCCEEEHHHHCCE
YTWAFDNNLSVSKQKGINYELHVQSKGWMGNVANSMTSGTVGLGLRAEAMKISLSGMPYS
EEEEECCCCCCHHHCCCCEEEEECCCCCCCHHHHCCCCCCEECCEEEEEEEEEECCCCCC
GDIQYRSHVQGSGWQGWLKNGEISGTRGQSKRLEAFQVKLTGNMAKNYSVQYRAHVQNKG
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCC
WQSWVKDGATAGTTGESLRIEAVQMRLVAK
HHHHHHCCCCCCCCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1429718; 1346764 [H]