Click here to switch to the map view.

The map label for this gene is pyrR

Identifier: 226224443

GI number: 226224443

Start: 1903837

End: 1904388

Strand: Reverse

Name: pyrR

Synonym: Lm4b_01856

Alternate gene names: 226224443

Gene position: 1904388-1903837 (Counterclockwise)

Preceding gene: 226224446

Following gene: 226224442

Centisome position: 65.38

GC content: 42.57

Gene sequence:

>552_bases
ATGCAAAAACAAGTAGTTGTCATGGACGAGGCGGCAATCAAACGTGCGCTCACTCGAGTAAGTTACGAAATCATCGAGCG
GAATAAAGGCACGAAGAATTTAGCGCTTGTCGGTATTAAGACGCGTGGTATCTATCTTGCAGAGCGTTTGCATAAGCGTA
TACTTGAAATTGAGGGTATTGATGTTCCAGTTGGAGATATTGATATTACACTTTACCGAGATGATTTATCTTTCAAAGAT
GATAAGACTCGCGAACCCGCTGTACATGGGACGAACATTCCATTCGATATTAATGGAAAAAAAGTCGTTCTTGTAGATGA
TGTGCTTTATACAGGTCGAACTGTGCGTGCCGCAATGGACGCATTAATGGATGTAGGTAGACCTGCGCAAATTCACCTTG
CAGTGCTTGCTGATCGGGGCCATAGAGAGCTACCGATTAGAGCAGATTATGTAGGGAAAAACATTCCGACATCAGGAAAC
GAACGAGTAGAAGTTCGCCTAACCGATGTGGACAACGAAGAAGATGCGGTTATTATTAACAAAAATGAATAA

Upstream 100 bases:

>100_bases
GAAGGTGACGATAATTTGACGGGTTAATTGTATACTCGTACGCGTTCCCTTGCTTACACTGGCAGAGGGTTATTTTTTTG
CACAAAAGGAGAGATTTCGG

Downstream 100 bases:

>100_bases
CAATGTAACACTTTTTTAAAAGCAGTCCTGTGAGGCTGACAAAGAGTGATTAATTTCTATAGGGGATTATTCTATACTCT
TTGTCGACACAGACAAGGGG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MQKQVVVMDEAAIKRALTRVSYEIIERNKGTKNLALVGIKTRGIYLAERLHKRILEIEGIDVPVGDIDITLYRDDLSFKD
DKTREPAVHGTNIPFDINGKKVVLVDDVLYTGRTVRAAMDALMDVGRPAQIHLAVLADRGHRELPIRADYVGKNIPTSGN
ERVEVRLTDVDNEEDAVIINKNE

Sequences:

>Translated_183_residues
MQKQVVVMDEAAIKRALTRVSYEIIERNKGTKNLALVGIKTRGIYLAERLHKRILEIEGIDVPVGDIDITLYRDDLSFKD
DKTREPAVHGTNIPFDINGKKVVLVDDVLYTGRTVRAAMDALMDVGRPAQIHLAVLADRGHRELPIRADYVGKNIPTSGN
ERVEVRLTDVDNEEDAVIINKNE
>Mature_183_residues
MQKQVVVMDEAAIKRALTRVSYEIIERNKGTKNLALVGIKTRGIYLAERLHKRILEIEGIDVPVGDIDITLYRDDLSFKD
DKTREPAVHGTNIPFDINGKKVVLVDDVLYTGRTVRAAMDALMDVGRPAQIHLAVLADRGHRELPIRADYVGKNIPTSGN
ERVEVRLTDVDNEEDAVIINKNE

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20539; Mature: 20539

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKQVVVMDEAAIKRALTRVSYEIIERNKGTKNLALVGIKTRGIYLAERLHKRILEIEGI
CCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHEECCC
DVPVGDIDITLYRDDLSFKDDKTREPAVHGTNIPFDINGKKVVLVDDVLYTGRTVRAAMD
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCEEEEEECEECCCCHHHHHHH
ALMDVGRPAQIHLAVLADRGHRELPIRADYVGKNIPTSGNERVEVRLTDVDNEEDAVIIN
HHHHCCCCCEEEEEEEECCCCCCCCEEHHHCCCCCCCCCCCEEEEEEEECCCCCCEEEEE
KNE
CCC
>Mature Secondary Structure
MQKQVVVMDEAAIKRALTRVSYEIIERNKGTKNLALVGIKTRGIYLAERLHKRILEIEGI
CCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHEECCC
DVPVGDIDITLYRDDLSFKDDKTREPAVHGTNIPFDINGKKVVLVDDVLYTGRTVRAAMD
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCEEEEEECEECCCCHHHHHHH
ALMDVGRPAQIHLAVLADRGHRELPIRADYVGKNIPTSGNERVEVRLTDVDNEEDAVIIN
HHHHCCCCCEEEEEEEECCCCCCCCEEHHHCCCCCCCCCCCEEEEEEEECCCCCCEEEEE
KNE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]