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The map label for this gene is pyrDII

Identifier: 226224437

GI number: 226224437

Start: 1895082

End: 1895846

Strand: Reverse

Name: pyrDII

Synonym: Lm4b_01850

Alternate gene names: 226224437

Gene position: 1895846-1895082 (Counterclockwise)

Preceding gene: 226224438

Following gene: 226224436

Centisome position: 65.09

GC content: 42.88

Gene sequence:

>765_bases
GTGTTACAGACGGAAATGAAGGTCATTCAGCAAACCGAAATTGCAGATAAAGTATACGAATTAATTTTGACAGGGGAACG
TGTAGCCGATATGTCACCGGGACAGTTTTTAATGCTGAAACCGAGTCGTTCTGATTTACTTATGAGACGACCGATAAGTA
TTTGTTCTTACGATAAAACCGCAAAGACATGCATTCTGTTGTACCGGATAGAAGGTGACGGGACAAGAGATTTCAGTAAA
CTTTCAGAAGGGGATACTATCGATGTGTTAGGTCCGCTTGGAAAAGGATTCGATATCGACCAGACACCTGCACCAAAAAC
CGCTCTTTTAATCGGGGGTGGAATTGGTGTCCCTCCTATGTATCAACTCGGTAAAGAGTTAGCTGGAAAAGGCGTACAAG
TCACGTTTGTAAATGGATTCCAATCTGCGAAAGATAGTTTTTATGAAAAAGAAATGAATGCATATGGCACAGTTCATATT
GCGACGGTGGACGGCTCACTTGGAACACAAGGTTTCGTCACAGACATCACGAACAATTTTCCAGAAGAACCAGATGTCAT
CTATAGTTGCGGACCAAAAGCGATGCTCCAGGCCGTGAAAGCTAGTTTTCCGGAAACGAAAACATATCTTTCTTTAGAAG
AACGAATGGCATGCGGTATTGGGGCTTGCTACGCTTGTGTTTGTCCAAAAGCAGATGATGCGAAAAAACAATTTAAAGTG
TGCGAAGACGGCCCAGTATTTCGTGCGGATGAGGTGAGTTTATGA

Upstream 100 bases:

>100_bases
CGTGTACTGGAATCGCGCTCTTTTGAACTCGAATCGATGAATACCAGTGAAGTAAAACAACCTAAAGCACGTGTTTAAAT
AGAAGAAACGGGGTGGAACC

Downstream 100 bases:

>100_bases
ACCGATTAGCAGTAGAAATTCCTGGATTATCGCTCAAAAACCCGATTATGCCAGCATCAGGATGTTTTGGCTTCGGACAA
GAATATAGCAAATACTATGA

Product: dihydroorotate dehydrogenase (electron transfer subunit)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLQTEMKVIQQTEIADKVYELILTGERVADMSPGQFLMLKPSRSDLLMRRPISICSYDKTAKTCILLYRIEGDGTRDFSK
LSEGDTIDVLGPLGKGFDIDQTPAPKTALLIGGGIGVPPMYQLGKELAGKGVQVTFVNGFQSAKDSFYEKEMNAYGTVHI
ATVDGSLGTQGFVTDITNNFPEEPDVIYSCGPKAMLQAVKASFPETKTYLSLEERMACGIGACYACVCPKADDAKKQFKV
CEDGPVFRADEVSL

Sequences:

>Translated_254_residues
MLQTEMKVIQQTEIADKVYELILTGERVADMSPGQFLMLKPSRSDLLMRRPISICSYDKTAKTCILLYRIEGDGTRDFSK
LSEGDTIDVLGPLGKGFDIDQTPAPKTALLIGGGIGVPPMYQLGKELAGKGVQVTFVNGFQSAKDSFYEKEMNAYGTVHI
ATVDGSLGTQGFVTDITNNFPEEPDVIYSCGPKAMLQAVKASFPETKTYLSLEERMACGIGACYACVCPKADDAKKQFKV
CEDGPVFRADEVSL
>Mature_254_residues
MLQTEMKVIQQTEIADKVYELILTGERVADMSPGQFLMLKPSRSDLLMRRPISICSYDKTAKTCILLYRIEGDGTRDFSK
LSEGDTIDVLGPLGKGFDIDQTPAPKTALLIGGGIGVPPMYQLGKELAGKGVQVTFVNGFQSAKDSFYEKEMNAYGTVHI
ATVDGSLGTQGFVTDITNNFPEEPDVIYSCGPKAMLQAVKASFPETKTYLSLEERMACGIGACYACVCPKADDAKKQFKV
CEDGPVFRADEVSL

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 27642; Mature: 27642

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTEMKVIQQTEIADKVYELILTGERVADMSPGQFLMLKPSRSDLLMRRPISICSYDKT
CCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEECCCCCCHHHHCCCHHHCCCCC
AKTCILLYRIEGDGTRDFSKLSEGDTIDVLGPLGKGFDIDQTPAPKTALLIGGGIGVPPM
CCEEEEEEEECCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCHH
YQLGKELAGKGVQVTFVNGFQSAKDSFYEKEMNAYGTVHIATVDGSLGTQGFVTDITNNF
HHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEHHHCCC
PEEPDVIYSCGPKAMLQAVKASFPETKTYLSLEERMACGIGACYACVCPKADDAKKQFKV
CCCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHEEECCCCCCCHHHHEE
CEDGPVFRADEVSL
CCCCCEECCCCCCC
>Mature Secondary Structure
MLQTEMKVIQQTEIADKVYELILTGERVADMSPGQFLMLKPSRSDLLMRRPISICSYDKT
CCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEECCCCCCHHHHCCCHHHCCCCC
AKTCILLYRIEGDGTRDFSKLSEGDTIDVLGPLGKGFDIDQTPAPKTALLIGGGIGVPPM
CCEEEEEEEECCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCHH
YQLGKELAGKGVQVTFVNGFQSAKDSFYEKEMNAYGTVHIATVDGSLGTQGFVTDITNNF
HHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEHHHCCC
PEEPDVIYSCGPKAMLQAVKASFPETKTYLSLEERMACGIGACYACVCPKADDAKKQFKV
CCCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHEEECCCCCCCHHHHEE
CEDGPVFRADEVSL
CCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]