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The map label for this gene is sdaAA [H]

Identifier: 226224415

GI number: 226224415

Start: 1873142

End: 1874032

Strand: Reverse

Name: sdaAA [H]

Synonym: Lm4b_01828

Alternate gene names: 226224415

Gene position: 1874032-1873142 (Counterclockwise)

Preceding gene: 226224416

Following gene: 226224414

Centisome position: 64.34

GC content: 45.9

Gene sequence:

>891_bases
ATGTTTAGAACTGTAGCAGAATTAGTAGATATCGCTGAACGCGAGAACTTAACTATTGCTGAAATTATGATCAAGCGTGA
AATGAATATTTCTGGTTTACCGCGGGAAGAAATAACAGCTGCGATGGAACGGAATTTAGATATTATGGAAGAAGCTATTC
GTGAAGGTGAGGCGGGAGTTACTTCTACAACTGGCTTAACAGGCGGAGATGCCGTCCTAATGCAAGACTATATCAAAAAA
GGAAACTTCTTATCAGGCGAAGTGTTACTTGATTCTGTAGCAAAAGCAATCGCGACGAATGAAGTTAATGCTTCGATGGG
CGTTATTTGCGCAACACCAACGGCAGGAAGCGCGGGGGTTGTACCGGGCGTACTTTTTTCCTTAAAAGATCGTCTAGAAA
TGTCGCGTGAGGATATGGTGAACTTTTTATTCACAGCAGGTGCCTTTGGGTATGTTGTTGCGAATAATGCTTTTATAAGT
GGAGCGGCTGGTGGCTGTCAGGCAGAAATTGGCTCAGCAAGTGCGATGGCTTCAGCGGCGATTGTAGCAGCAGCCGGTGG
GACGCCAGAACAATCAGCACACGCGATGGCTATGACAATGAAAAATATGCTTGGACTTGTGTGTGATCCTGTAGCAGGGC
TTGTAGAAGTTCCATGTGTTAAACGTAATGCCCTTGGTTCCTCGCAAGCAATTATTTCAGCAGATATGGCGCTCGCAGGT
ATTAAGAGCCGCATTCCATGTGATGAAGTAATTGAAGCAATGCACCGCGTAGGCTTACAAATGCCAAGCTCTTTAAGAGA
AACGGCAGAAGGAGGATTGGCGGCTACACCGACTGGACGTGCAATTCAGCGGAAGATTTTTGGACTGTCGCCAGAAGATA
AGCGTGAGTGA

Upstream 100 bases:

>100_bases
TGTGTAAAGCCAAATGTGCGTAAACAAAACGTGCATTTGGCTTTATTTTGAGTTGTAAATCAGGTATGTTGGTAAAGGGT
AAAGAAAGTGAGTGTGGACA

Downstream 100 bases:

>100_bases
ACTTAAACGAATCCCGACAACTGAAATCAAAGGAATTGGCGAAGAAACAGCGAAAACGTTAAAAGAGTTAGGTTTATCCA
CCGTGCATGATTTGCTTTGG

Product: L-serine dehydratase (alpha chain)

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MFRTVAELVDIAERENLTIAEIMIKREMNISGLPREEITAAMERNLDIMEEAIREGEAGVTSTTGLTGGDAVLMQDYIKK
GNFLSGEVLLDSVAKAIATNEVNASMGVICATPTAGSAGVVPGVLFSLKDRLEMSREDMVNFLFTAGAFGYVVANNAFIS
GAAGGCQAEIGSASAMASAAIVAAAGGTPEQSAHAMAMTMKNMLGLVCDPVAGLVEVPCVKRNALGSSQAIISADMALAG
IKSRIPCDEVIEAMHRVGLQMPSSLRETAEGGLAATPTGRAIQRKIFGLSPEDKRE

Sequences:

>Translated_296_residues
MFRTVAELVDIAERENLTIAEIMIKREMNISGLPREEITAAMERNLDIMEEAIREGEAGVTSTTGLTGGDAVLMQDYIKK
GNFLSGEVLLDSVAKAIATNEVNASMGVICATPTAGSAGVVPGVLFSLKDRLEMSREDMVNFLFTAGAFGYVVANNAFIS
GAAGGCQAEIGSASAMASAAIVAAAGGTPEQSAHAMAMTMKNMLGLVCDPVAGLVEVPCVKRNALGSSQAIISADMALAG
IKSRIPCDEVIEAMHRVGLQMPSSLRETAEGGLAATPTGRAIQRKIFGLSPEDKRE
>Mature_296_residues
MFRTVAELVDIAERENLTIAEIMIKREMNISGLPREEITAAMERNLDIMEEAIREGEAGVTSTTGLTGGDAVLMQDYIKK
GNFLSGEVLLDSVAKAIATNEVNASMGVICATPTAGSAGVVPGVLFSLKDRLEMSREDMVNFLFTAGAFGYVVANNAFIS
GAAGGCQAEIGSASAMASAAIVAAAGGTPEQSAHAMAMTMKNMLGLVCDPVAGLVEVPCVKRNALGSSQAIISADMALAG
IKSRIPCDEVIEAMHRVGLQMPSSLRETAEGGLAATPTGRAIQRKIFGLSPEDKRE

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=284, Percent_Identity=33.8028169014084, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1788116, Length=181, Percent_Identity=44.7513812154696, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789161, Length=285, Percent_Identity=32.9824561403509, Blast_Score=137, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 30844; Mature: 30844

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRTVAELVDIAERENLTIAEIMIKREMNISGLPREEITAAMERNLDIMEEAIREGEAGV
CHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCC
TSTTGLTGGDAVLMQDYIKKGNFLSGEVLLDSVAKAIATNEVNASMGVICATPTAGSAGV
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
VPGVLFSLKDRLEMSREDMVNFLFTAGAFGYVVANNAFISGAAGGCQAEIGSASAMASAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCEEECCCCCCHHHCCCHHHHHHHH
IVAAAGGTPEQSAHAMAMTMKNMLGLVCDPVAGLVEVPCVKRNALGSSQAIISADMALAG
HEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
IKSRIPCDEVIEAMHRVGLQMPSSLRETAEGGLAATPTGRAIQRKIFGLSPEDKRE
HHCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCEEECCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFRTVAELVDIAERENLTIAEIMIKREMNISGLPREEITAAMERNLDIMEEAIREGEAGV
CHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCC
TSTTGLTGGDAVLMQDYIKKGNFLSGEVLLDSVAKAIATNEVNASMGVICATPTAGSAGV
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
VPGVLFSLKDRLEMSREDMVNFLFTAGAFGYVVANNAFISGAAGGCQAEIGSASAMASAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCEEECCCCCCHHHCCCHHHHHHHH
IVAAAGGTPEQSAHAMAMTMKNMLGLVCDPVAGLVEVPCVKRNALGSSQAIISADMALAG
HEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
IKSRIPCDEVIEAMHRVGLQMPSSLRETAEGGLAATPTGRAIQRKIFGLSPEDKRE
HHCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCEEECCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]