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The map label for this gene is fnr [H]

Identifier: 226223854

GI number: 226223854

Start: 1261191

End: 1261850

Strand: Direct

Name: fnr [H]

Synonym: Lm4b_01259

Alternate gene names: 226223854

Gene position: 1261191-1261850 (Clockwise)

Preceding gene: 226223851

Following gene: 226223856

Centisome position: 43.3

GC content: 33.48

Gene sequence:

>660_bases
ATGAAGCAAAATATTCTTAATAATTATGTGAGCACAAATGATTTTCCAGTTATTACAAGGGGAAAACGTAAATATTTAAC
TTACGAAGGACTTGAAGATTCATATGTGTACATACTTAAAAAAGGGATTATTAAAACGAGTATTATTTCAAGGGATGGCA
GGGAATTTAATTTAAACTACATTAATAAAATGGACATTATCTCACTTTTAAAAGATGAGTATTCGCAGTTTGCCAATGCG
CCGTTTAACATTCGTGTGGAGTCAGACACAGCAGAACTATATCAAGTTGACCGGGTAAGGTTTTGGAAAGACGTGAATCG
TGATGTGGATTTGCAAATTTATGTGAAAGATTATTACCGTACGAGGCTGCTACAATCCATAAAAAAAATGCAGCAAATGC
TAATGAATGGGAAACTTGGAGCAATTTGTACGCAACTCTATGAACTTTATACGCTTTTTGGAGTGGAAATTGCGCCTGAT
CAGTATTTGATTGATTTTCTAGTAAGTAATGAAGAAATTGGTCATTTTTGCGGGATTAACTCCGCAAGCAGTGTGAACCG
GATTTTCCAACAACTCAAAAAAGAAGGCGTCATTACGATGCAAAACCGCTATATTATTATTAAAAAATTAGATGTTATTC
AAGAAAACGTTATTTTTTAA

Upstream 100 bases:

>100_bases
GATATATACAAATTTGTATAACATATGTTGAAAAAATAGGGAATAGTATTTTGTATGATTAATATGCTTTAACTGGAATG
ACAAAAAGGAGGTTAAGAAC

Downstream 100 bases:

>100_bases
CAGTAGAAAAGCACTGCAATCAATATTTGCAGTGCTTTTCTATCCTCTTTTTTTAAATGAATATCGAATCCTAAGTGTGA
TGAGCCCGATGATGATTAAT

Product: regulator of the Fnr CRP family (including PrfA)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKQNILNNYVSTNDFPVITRGKRKYLTYEGLEDSYVYILKKGIIKTSIISRDGREFNLNYINKMDIISLLKDEYSQFANA
PFNIRVESDTAELYQVDRVRFWKDVNRDVDLQIYVKDYYRTRLLQSIKKMQQMLMNGKLGAICTQLYELYTLFGVEIAPD
QYLIDFLVSNEEIGHFCGINSASSVNRIFQQLKKEGVITMQNRYIIIKKLDVIQENVIF

Sequences:

>Translated_219_residues
MKQNILNNYVSTNDFPVITRGKRKYLTYEGLEDSYVYILKKGIIKTSIISRDGREFNLNYINKMDIISLLKDEYSQFANA
PFNIRVESDTAELYQVDRVRFWKDVNRDVDLQIYVKDYYRTRLLQSIKKMQQMLMNGKLGAICTQLYELYTLFGVEIAPD
QYLIDFLVSNEEIGHFCGINSASSVNRIFQQLKKEGVITMQNRYIIIKKLDVIQENVIF
>Mature_219_residues
MKQNILNNYVSTNDFPVITRGKRKYLTYEGLEDSYVYILKKGIIKTSIISRDGREFNLNYINKMDIISLLKDEYSQFANA
PFNIRVESDTAELYQVDRVRFWKDVNRDVDLQIYVKDYYRTRLLQSIKKMQQMLMNGKLGAICTQLYELYTLFGVEIAPD
QYLIDFLVSNEEIGHFCGINSASSVNRIFQQLKKEGVITMQNRYIIIKKLDVIQENVIF

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25782; Mature: 25782

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQNILNNYVSTNDFPVITRGKRKYLTYEGLEDSYVYILKKGIIKTSIISRDGREFNLNY
CCCCHHHHHCCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEECCCH
INKMDIISLLKDEYSQFANAPFNIRVESDTAELYQVDRVRFWKDVNRDVDLQIYVKDYYR
HHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
TRLLQSIKKMQQMLMNGKLGAICTQLYELYTLFGVEIAPDQYLIDFLVSNEEIGHFCGIN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEECCCHHHHHHHHCCCCCCHHCCCC
SASSVNRIFQQLKKEGVITMQNRYIIIKKLDVIQENVIF
CHHHHHHHHHHHHHCCCEEEECCEEEEEEHHHHHHHCCC
>Mature Secondary Structure
MKQNILNNYVSTNDFPVITRGKRKYLTYEGLEDSYVYILKKGIIKTSIISRDGREFNLNY
CCCCHHHHHCCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEECCCH
INKMDIISLLKDEYSQFANAPFNIRVESDTAELYQVDRVRFWKDVNRDVDLQIYVKDYYR
HHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
TRLLQSIKKMQQMLMNGKLGAICTQLYELYTLFGVEIAPDQYLIDFLVSNEEIGHFCGIN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEECCCHHHHHHHHCCCCCCHHCCCC
SASSVNRIFQQLKKEGVITMQNRYIIIKKLDVIQENVIF
CHHHHHHHHHHHHHCCCEEEECCEEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]