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The map label for this gene is gpmA [H]

Identifier: 226223847

GI number: 226223847

Start: 1256142

End: 1256741

Strand: Direct

Name: gpmA [H]

Synonym: Lm4b_01252

Alternate gene names: 226223847

Gene position: 1256142-1256741 (Clockwise)

Preceding gene: 226223844

Following gene: 226223849

Centisome position: 43.13

GC content: 37.67

Gene sequence:

>600_bases
ATGAAAAAGACATTGTATTTAATGCGCCACGGTCAAACATTATTTAATCAACGTAAAAAAATTCAAGGTTTTTGCGATGC
ACCACTTACCGAACTCGGGATTAAACAAGCAAAAATCGCTGGTAGTTACTTTAAAGAAAACAATATAACATTCGATCAAG
CTTACAGTTCCACATCAGAGCGCGCATCTGACACGTTAGAGCTGATTACGGACAAAAGCTATCAACGGTTGAAAGGTTTG
AAAGAATGGAATTTTGGTACTTTTGAAGGCGAGAGCGAAGACCTAAATCCACCGCTACCATATGGAGATTTTTTTGCTGC
GTATGGGGGAGAGCGAGAAGTGGATTTCAGAGATCGTTTAGTAGCAACAATGGAACGTATCATGAGCCAAGATAATCATG
ATACTGTCCTTGCCGTTTCTCACGGAGCTGCCTGTGCCCAATTTGCTAGATATTGGGAAAAAACAAGCAAAATTGGCAAA
GTAACAGGACTGAAGAATTGCTGCATTTTAAAGTTTGAATATGAAAATGGCAGATTTACTTTAGTTAATTTTATTAATCA
TGATTTTGAGAATGGAACGCATATAGAAAGCACTAAATAA

Upstream 100 bases:

>100_bases
ATACTGCGTGAAAGAGGAAAAATTAAGAAGATAAATACTTGACTTGGAGTTACTCCAGGGTGATAAACTAAAGAGAAGAT
ATAGATTCGGAGGAATTTAG

Downstream 100 bases:

>100_bases
AAAAGCACTCGTCATTGAGTGCTTTTTCGCTTCATTGAAACAAATTCTTTATTTTATCCAAAAATCCACCAGTTAACTCA
TTCGCAGTATCTTGCAAGTT

Product: phosphoglycerate mutase 1

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MKKTLYLMRHGQTLFNQRKKIQGFCDAPLTELGIKQAKIAGSYFKENNITFDQAYSSTSERASDTLELITDKSYQRLKGL
KEWNFGTFEGESEDLNPPLPYGDFFAAYGGEREVDFRDRLVATMERIMSQDNHDTVLAVSHGAACAQFARYWEKTSKIGK
VTGLKNCCILKFEYENGRFTLVNFINHDFENGTHIESTK

Sequences:

>Translated_199_residues
MKKTLYLMRHGQTLFNQRKKIQGFCDAPLTELGIKQAKIAGSYFKENNITFDQAYSSTSERASDTLELITDKSYQRLKGL
KEWNFGTFEGESEDLNPPLPYGDFFAAYGGEREVDFRDRLVATMERIMSQDNHDTVLAVSHGAACAQFARYWEKTSKIGK
VTGLKNCCILKFEYENGRFTLVNFINHDFENGTHIESTK
>Mature_199_residues
MKKTLYLMRHGQTLFNQRKKIQGFCDAPLTELGIKQAKIAGSYFKENNITFDQAYSSTSERASDTLELITDKSYQRLKGL
KEWNFGTFEGESEDLNPPLPYGDFFAAYGGEREVDFRDRLVATMERIMSQDNHDTVLAVSHGAACAQFARYWEKTSKIGK
VTGLKNCCILKFEYENGRFTLVNFINHDFENGTHIESTK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324857, Length=162, Percent_Identity=31.4814814814815, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 22784; Mature: 22784

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLYLMRHGQTLFNQRKKIQGFCDAPLTELGIKQAKIAGSYFKENNITFDQAYSSTSE
CCCEEEEECCCHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHCCHHH
RASDTLELITDKSYQRLKGLKEWNFGTFEGESEDLNPPLPYGDFFAAYGGEREVDFRDRL
HHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHH
VATMERIMSQDNHDTVLAVSHGAACAQFARYWEKTSKIGKVTGLKNCCILKFEYENGRFT
HHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEE
LVNFINHDFENGTHIESTK
EEEEHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKKTLYLMRHGQTLFNQRKKIQGFCDAPLTELGIKQAKIAGSYFKENNITFDQAYSSTSE
CCCEEEEECCCHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHCCHHH
RASDTLELITDKSYQRLKGLKEWNFGTFEGESEDLNPPLPYGDFFAAYGGEREVDFRDRL
HHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHH
VATMERIMSQDNHDTVLAVSHGAACAQFARYWEKTSKIGKVTGLKNCCILKFEYENGRFT
HHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEE
LVNFINHDFENGTHIESTK
EEEEHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA