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The map label for this gene is yggV [C]

Identifier: 226223839

GI number: 226223839

Start: 1246062

End: 1246673

Strand: Direct

Name: yggV [C]

Synonym: Lm4b_01244

Alternate gene names: 226223839

Gene position: 1246062-1246673 (Clockwise)

Preceding gene: 226223838

Following gene: 226223840

Centisome position: 42.78

GC content: 40.36

Gene sequence:

>612_bases
ATGAGTAAAATTATTATCGCTACCGCAAACAAAGGAAAAGCAAAAGAATTCGAAAAAATCTTTGCGAAATTTAATATCGA
AGTAGCAACCCTTGCTGATTTTCCAGAAATTGGTGAAATAGAAGAAACTGGAACAACCTTTGCCGAAAATGCCGCTCTTA
AAGCAGAAACGGTCGCTAGCGTGTTAAATCAAACCGTCATTGCTGATGATTCTGGTTTAATCGTAGACGCGCTTGACGGA
GCTCCTGGCGTCTATTCCGCACGTTATGCAGGTATCGCTCACGATGATGCCAAAAATAACGAAAAACTACTTAAAAACTT
AGAAGGTGTTGAACCGGACAAAAGAACGGCTCGTTTCCACTGTACACTTGCTGTAGCCACACCTTCTGAGAAAACATCTT
TTTATACCGGTGAAGTAGAGGGCGTTATCGCAGAACAACTATGCGGCACAAATGGCTTTGGCTATGATCCACTATTTTTC
TTACCAGAATTCGGTCTAACAATGGCAGAAATTCCAGCGGAGAAAAAGAATGAAATCAGCCACCGTGCTAATGCCATTAA
ACAACTAGAAAAAGATTTAGCAGAAGTAGTAGAAAAAGTAACCAAAAAGTGA

Upstream 100 bases:

>100_bases
ACTAATTGCCTTAGGTAAAAAAGGAATTAGCGAATTAATCGAAATCCAAAAAGAAACACTCGGAGACAAAGTCACAGCGC
GGATTAAAGGAGAATAAAAA

Downstream 100 bases:

>100_bases
GAAAATAAGTAACAGTATCACGGGGGAGGAAACAAAATGAAATTATTAGTAGTTAGCGACAGCCACTCAGAACGTGACTG
CTTAATCCATCTTAAAGAAA

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVASVLNQTVIADDSGLIVDALDG
APGVYSARYAGIAHDDAKNNEKLLKNLEGVEPDKRTARFHCTLAVATPSEKTSFYTGEVEGVIAEQLCGTNGFGYDPLFF
LPEFGLTMAEIPAEKKNEISHRANAIKQLEKDLAEVVEKVTKK

Sequences:

>Translated_203_residues
MSKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVASVLNQTVIADDSGLIVDALDG
APGVYSARYAGIAHDDAKNNEKLLKNLEGVEPDKRTARFHCTLAVATPSEKTSFYTGEVEGVIAEQLCGTNGFGYDPLFF
LPEFGLTMAEIPAEKKNEISHRANAIKQLEKDLAEVVEKVTKK
>Mature_202_residues
SKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVASVLNQTVIADDSGLIVDALDGA
PGVYSARYAGIAHDDAKNNEKLLKNLEGVEPDKRTARFHCTLAVATPSEKTSFYTGEVEGVIAEQLCGTNGFGYDPLFFL
PEFGLTMAEIPAEKKNEISHRANAIKQLEKDLAEVVEKVTKK

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=191, Percent_Identity=46.0732984293194, Blast_Score=167, Evalue=6e-43,
Organism=Drosophila melanogaster, GI19920712, Length=198, Percent_Identity=31.3131313131313, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21970; Mature: 21839

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVAS
CCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHCCCCHHHCCHHHHHHHHH
VLNQTVIADDSGLIVDALDGAPGVYSARYAGIAHDDAKNNEKLLKNLEGVEPDKRTARFH
HHHHHEEECCCCEEEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEE
CTLAVATPSEKTSFYTGEVEGVIAEQLCGTNGFGYDPLFFLPEFGLTMAEIPAEKKNEIS
EEEEEECCCCCCEEECCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHCCCHHHHHHH
HRANAIKQLEKDLAEVVEKVTKK
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVAS
CEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHCCCCHHHCCHHHHHHHHH
VLNQTVIADDSGLIVDALDGAPGVYSARYAGIAHDDAKNNEKLLKNLEGVEPDKRTARFH
HHHHHEEECCCCEEEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEE
CTLAVATPSEKTSFYTGEVEGVIAEQLCGTNGFGYDPLFFLPEFGLTMAEIPAEKKNEIS
EEEEEECCCCCCEEECCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHCCCHHHHHHH
HRANAIKQLEKDLAEVVEKVTKK
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]