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The map label for this gene is lytG [H]

Identifier: 226223816

GI number: 226223816

Start: 1217517

End: 1218503

Strand: Direct

Name: lytG [H]

Synonym: Lm4b_01221

Alternate gene names: 226223816

Gene position: 1217517-1218503 (Clockwise)

Preceding gene: 226223815

Following gene: 226223817

Centisome position: 41.8

GC content: 38.1

Gene sequence:

>987_bases
GTGACAATTGGACTTGGAATTACAATTACATTATTTGCAGTACCAATCCACTCCCAAGCTGCTGGTCTAGAGGACGGCTT
GACTTCCAAGCAAGAGAAGTTTATTAATGAGATTGCGCCGCATGCTCAAAAAGTGCAAAAAGAACATGGTATTTTAGCTA
GTATTACGATTTCGCAAGCAATCCTAGAGTCCAATTGGGGCGAAAGTAAATTAGCAAAAGATGGCAATAATTTATTCGGA
ATTAAAGGTTCCTATCAAGGAGCTTCTATTAAATTACCTACCAAAGAACATAATGGCGTTGTTTGGGTTGGAACAGATGC
TGTTTTCCGTGCGTACCCAGGTTGGTATGAATCAATGAATGACCACGCACTTTTATTTGTCAATGGACCGTCTTGGAACC
CTCATTTATACGGAGGACTAATCAAAGAATATGACTTTGAAAAGGCAGCTATTGCCCTTGGAAAAACAGGCTATTCATCT
GATCCAGAGTATGCAGCGAAATTAATTGAACTGATCAAAAAAGCAAATTTAAATAAATACGATACCGTTTATAGCGAACG
TGTATCAGACAAAGCAATTAAGGCTGCTGGAGAAGTAGCTGTCAAAGATAATTGCTATGTTTGGTCTGCTCCGGGTGGCA
CAAAAGGTGCGAAACCTATCGTCAGCACTACCAAATACTTTGGCCGTCAAGTTTCTATTAATCAAGAAGTAAAAGTAACA
GATTCCAATATTTCTTGGTACCATATCCATCAAAATGGAGAATCCATCGGTTGGATTGAAAGTACATCGATTAAAGACTT
CTATCAATTAGAAGACTATGCGCCAACAGTAGATGCATTACTAAAAACAGATGACAACAATCGTTTAGTAATCAATATGG
ATATCGATACATCTGAGCTACACAAAACAAAACTAGCAAAGGCAGATACCAAAGAGAAAACTGCCTTTAATTTACCTTTA
CTGAACGTTCAATCCATCATCTGGTAA

Upstream 100 bases:

>100_bases
TTTAAAGAACACTAGTTTCCAGTTTTTCAAAAGCTGGAAGGATAAATCAAAGAAGGATGTGCAATAAATCATTATGTTAC
AGCTCGCAAAGAAGCATTTG

Downstream 100 bases:

>100_bases
TAACCTTGCAAAAAAAGCTGAATAGATTACTCGGCTTTTTTTGCGTTTTCAAAGGATTTTTAGAAAGAAACTGTTATAAT
GAAAATGGAGTTTATAAGGA

Product: N-acetylmuramoyl-L-alanine amidase (autolysin)

Products: NA

Alternate protein names: Autolysin lytG; Exo-beta-N-acetylglucosaminidase lytG; Peptidoglycan hydrolase lytG [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTIGLGITITLFAVPIHSQAAGLEDGLTSKQEKFINEIAPHAQKVQKEHGILASITISQAILESNWGESKLAKDGNNLFG
IKGSYQGASIKLPTKEHNGVVWVGTDAVFRAYPGWYESMNDHALLFVNGPSWNPHLYGGLIKEYDFEKAAIALGKTGYSS
DPEYAAKLIELIKKANLNKYDTVYSERVSDKAIKAAGEVAVKDNCYVWSAPGGTKGAKPIVSTTKYFGRQVSINQEVKVT
DSNISWYHIHQNGESIGWIESTSIKDFYQLEDYAPTVDALLKTDDNNRLVINMDIDTSELHKTKLAKADTKEKTAFNLPL
LNVQSIIW

Sequences:

>Translated_328_residues
MTIGLGITITLFAVPIHSQAAGLEDGLTSKQEKFINEIAPHAQKVQKEHGILASITISQAILESNWGESKLAKDGNNLFG
IKGSYQGASIKLPTKEHNGVVWVGTDAVFRAYPGWYESMNDHALLFVNGPSWNPHLYGGLIKEYDFEKAAIALGKTGYSS
DPEYAAKLIELIKKANLNKYDTVYSERVSDKAIKAAGEVAVKDNCYVWSAPGGTKGAKPIVSTTKYFGRQVSINQEVKVT
DSNISWYHIHQNGESIGWIESTSIKDFYQLEDYAPTVDALLKTDDNNRLVINMDIDTSELHKTKLAKADTKEKTAFNLPL
LNVQSIIW
>Mature_327_residues
TIGLGITITLFAVPIHSQAAGLEDGLTSKQEKFINEIAPHAQKVQKEHGILASITISQAILESNWGESKLAKDGNNLFGI
KGSYQGASIKLPTKEHNGVVWVGTDAVFRAYPGWYESMNDHALLFVNGPSWNPHLYGGLIKEYDFEKAAIALGKTGYSSD
PEYAAKLIELIKKANLNKYDTVYSERVSDKAIKAAGEVAVKDNCYVWSAPGGTKGAKPIVSTTKYFGRQVSINQEVKVTD
SNISWYHIHQNGESIGWIESTSIKDFYQLEDYAPTVDALLKTDDNNRLVINMDIDTSELHKTKLAKADTKEKTAFNLPLL
NVQSIIW

Specific function: Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility, chemotaxis and cell division [H]

COG id: COG1705

COG function: function code NU; Muramidase (flagellum-specific)

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 73 family [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=157, Percent_Identity=28.0254777070064, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000423
- InterPro:   IPR013338
- InterPro:   IPR002901 [H]

Pfam domain/function: PF01832 Glucosaminidase [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 36211; Mature: 36080

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIGLGITITLFAVPIHSQAAGLEDGLTSKQEKFINEIAPHAQKVQKEHGILASITISQA
CEEECEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHH
ILESNWGESKLAKDGNNLFGIKGSYQGASIKLPTKEHNGVVWVGTDAVFRAYPGWYESMN
HHHCCCCCHHHHCCCCCEEEECCCCCCCEEECCCCCCCCEEEEECCHHHHCCCCHHHCCC
DHALLFVNGPSWNPHLYGGLIKEYDFEKAAIALGKTGYSSDPEYAAKLIELIKKANLNKY
CCEEEEEECCCCCCHHHCCHHHHCCCCHHEEEECCCCCCCCHHHHHHHHHHHHHCCCCHH
DTVYSERVSDKAIKAAGEVAVKDNCYVWSAPGGTKGAKPIVSTTKYFGRQVSINQEVKVT
HHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCCCCCCCHHHHHHHCCEEECCCCEEEEE
DSNISWYHIHQNGESIGWIESTSIKDFYQLEDYAPTVDALLKTDDNNRLVINMDIDTSEL
ECCEEEEEEECCCCEECEEECCCCHHHHHHHCCCCCHHHHEEECCCCEEEEEECCCHHHH
HKTKLAKADTKEKTAFNLPLLNVQSIIW
HHHHHHCCCCCCCEEECCCCCCHHHHCC
>Mature Secondary Structure 
TIGLGITITLFAVPIHSQAAGLEDGLTSKQEKFINEIAPHAQKVQKEHGILASITISQA
EEECEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHH
ILESNWGESKLAKDGNNLFGIKGSYQGASIKLPTKEHNGVVWVGTDAVFRAYPGWYESMN
HHHCCCCCHHHHCCCCCEEEECCCCCCCEEECCCCCCCCEEEEECCHHHHCCCCHHHCCC
DHALLFVNGPSWNPHLYGGLIKEYDFEKAAIALGKTGYSSDPEYAAKLIELIKKANLNKY
CCEEEEEECCCCCCHHHCCHHHHCCCCHHEEEECCCCCCCCHHHHHHHHHHHHHCCCCHH
DTVYSERVSDKAIKAAGEVAVKDNCYVWSAPGGTKGAKPIVSTTKYFGRQVSINQEVKVT
HHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCCCCCCCHHHHHHHCCEEECCCCEEEEE
DSNISWYHIHQNGESIGWIESTSIKDFYQLEDYAPTVDALLKTDDNNRLVINMDIDTSEL
ECCEEEEEEECCCCEECEEECCCCHHHHHHHCCCCCHHHHEEECCCCEEEEEECCCHHHH
HKTKLAKADTKEKTAFNLPLLNVQSIIW
HHHHHHCCCCCCCEEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]