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The map label for this gene is 226223765

Identifier: 226223765

GI number: 226223765

Start: 1172887

End: 1173882

Strand: Direct

Name: 226223765

Synonym: Lm4b_01169

Alternate gene names: NA

Gene position: 1172887-1173882 (Clockwise)

Preceding gene: 226223764

Following gene: 226223766

Centisome position: 40.27

GC content: 40.86

Gene sequence:

>996_bases
GTGAGTATTTATACCAAAACCGGCGATAAGGGAACGACTGCATTATTTGATGGGAATCGTGTGAAAAAATATGATGACCG
TGTCGAAACCTATGGCTCGTTTGATGAGCTGAATGCAGAAATTAGTGTAGCAGAAAAATTCGTGACTTCAGCTGAGAATA
AGACTTTGCTTAGAAACGTGGAGCGGCAGTTGTTTTACGTTTGCGCAGAACTTGCAACAGAGCACGAAGCATCCCTCGCT
AGCAAAATTATTATTACAGAAAACGACATCAATCAACTTGAAAAAGTCATTGATGATTACACTGCAAAATTGCCAAAAGT
CGATAGTTTTGTTCTTCCTGGATCAAGCACAGCAGGAGCATTTCTTCATAGCGCCAGGACTGTTGCTAGGCGTGGTGAGC
GATTATTAGTTCGTTTGTCAGAACAAACAGCTATCCGAAAAGAGTTATTAAAATTTGTAAATCGCTTATCGGATTTCTTG
TATATTCTTGCTAGAGAAGAAGATTTCAGACAAATGCTCGATAAGGCAACCAAGCTCATTGTTGCCAAATACTTAGAGCA
AACGGGCCAAGAAAAGTCAGTTACATGCGATTTGTCTTTTTCCTTTTGTGAAAAATTAATGCACCAAGTTTGCATCGTTT
CAGAAGAAATTGGCGTTCCAGTCACACTTGCTATTGTCGATGCGCACGGTAATGTCAGATTTAATTACCGGATGGAGCAC
GCTCTTTTAGTAAGTGCAGAACTGGCAACGAAAAAAGCCTATTCCGCCGTAGCGATGAAAACAAGCACGGAAAAATTAAC
AGAAGCAGTTCAGCCAGGAGCCCCACTTTATCAATTAGAAACACTGACAAATGGTGATATTGTAACCTTTGGCGGTGGTG
TTCCAATCTACGGAAAAGATGGAGCTATTATTGGTGGAATGGGGATTAGCGGCGGATCAGTGGAAGAGGATATCCACATT
GCAAAAAAAGCATTATCAATGATAGAGAAGGGGTAA

Upstream 100 bases:

>100_bases
GCAATGCAGCTAGAAGTGTTTTTGCGGAACCAAATAGTGCGATTGATTCGGCAATTATTGCAATTGTCGATAGTTTTGAT
AAGTAAGGAGTGAATAACTC

Downstream 100 bases:

>100_bases
TTCTGTATGGAATCATTAGAACTCGAACAACTGGTAAAAAAAGTTCTTTTAGAAAAATTAGCAGAACAAAAAGATGCACC
AGTAAAAACAACGGTCAAAG

Product: PduO protein

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; ORFW [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSIYTKTGDKGTTALFDGNRVKKYDDRVETYGSFDELNAEISVAEKFVTSAENKTLLRNVERQLFYVCAELATEHEASLA
SKIIITENDINQLEKVIDDYTAKLPKVDSFVLPGSSTAGAFLHSARTVARRGERLLVRLSEQTAIRKELLKFVNRLSDFL
YILAREEDFRQMLDKATKLIVAKYLEQTGQEKSVTCDLSFSFCEKLMHQVCIVSEEIGVPVTLAIVDAHGNVRFNYRMEH
ALLVSAELATKKAYSAVAMKTSTEKLTEAVQPGAPLYQLETLTNGDIVTFGGGVPIYGKDGAIIGGMGISGGSVEEDIHI
AKKALSMIEKG

Sequences:

>Translated_331_residues
MSIYTKTGDKGTTALFDGNRVKKYDDRVETYGSFDELNAEISVAEKFVTSAENKTLLRNVERQLFYVCAELATEHEASLA
SKIIITENDINQLEKVIDDYTAKLPKVDSFVLPGSSTAGAFLHSARTVARRGERLLVRLSEQTAIRKELLKFVNRLSDFL
YILAREEDFRQMLDKATKLIVAKYLEQTGQEKSVTCDLSFSFCEKLMHQVCIVSEEIGVPVTLAIVDAHGNVRFNYRMEH
ALLVSAELATKKAYSAVAMKTSTEKLTEAVQPGAPLYQLETLTNGDIVTFGGGVPIYGKDGAIIGGMGISGGSVEEDIHI
AKKALSMIEKG
>Mature_330_residues
SIYTKTGDKGTTALFDGNRVKKYDDRVETYGSFDELNAEISVAEKFVTSAENKTLLRNVERQLFYVCAELATEHEASLAS
KIIITENDINQLEKVIDDYTAKLPKVDSFVLPGSSTAGAFLHSARTVARRGERLLVRLSEQTAIRKELLKFVNRLSDFLY
ILAREEDFRQMLDKATKLIVAKYLEQTGQEKSVTCDLSFSFCEKLMHQVCIVSEEIGVPVTLAIVDAHGNVRFNYRMEHA
LLVSAELATKKAYSAVAMKTSTEKLTEAVQPGAPLYQLETLTNGDIVTFGGGVPIYGKDGAIIGGMGISGGSVEEDIHIA
KKALSMIEKG

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=168, Percent_Identity=37.5, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115534154, Length=198, Percent_Identity=31.3131313131313, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 36480; Mature: 36349

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYTKTGDKGTTALFDGNRVKKYDDRVETYGSFDELNAEISVAEKFVTSAENKTLLRNV
CCEEECCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCHHHHHHH
ERQLFYVCAELATEHEASLASKIIITENDINQLEKVIDDYTAKLPKVDSFVLPGSSTAGA
HHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCCCHHH
FLHSARTVARRGERLLVRLSEQTAIRKELLKFVNRLSDFLYILAREEDFRQMLDKATKLI
HHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHH
VAKYLEQTGQEKSVTCDLSFSFCEKLMHQVCIVSEEIGVPVTLAIVDAHGNVRFNYRMEH
HHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECE
ALLVSAELATKKAYSAVAMKTSTEKLTEAVQPGAPLYQLETLTNGDIVTFGGGVPIYGKD
EEEEHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCEEEECCC
GAIIGGMGISGGSVEEDIHIAKKALSMIEKG
CCEEECCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIYTKTGDKGTTALFDGNRVKKYDDRVETYGSFDELNAEISVAEKFVTSAENKTLLRNV
CEEECCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCHHHHHHH
ERQLFYVCAELATEHEASLASKIIITENDINQLEKVIDDYTAKLPKVDSFVLPGSSTAGA
HHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCCCHHH
FLHSARTVARRGERLLVRLSEQTAIRKELLKFVNRLSDFLYILAREEDFRQMLDKATKLI
HHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHH
VAKYLEQTGQEKSVTCDLSFSFCEKLMHQVCIVSEEIGVPVTLAIVDAHGNVRFNYRMEH
HHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECE
ALLVSAELATKKAYSAVAMKTSTEKLTEAVQPGAPLYQLETLTNGDIVTFGGGVPIYGKD
EEEEHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCEEEECCC
GAIIGGMGISGGSVEEDIHIAKKALSMIEKG
CCEEECCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA