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The map label for this gene is tarJ [H]

Identifier: 226223698

GI number: 226223698

Start: 1115708

End: 1116733

Strand: Direct

Name: tarJ [H]

Synonym: Lm4b_01100

Alternate gene names: 226223698

Gene position: 1115708-1116733 (Clockwise)

Preceding gene: 226223697

Following gene: 226223699

Centisome position: 38.31

GC content: 39.08

Gene sequence:

>1026_bases
ATGATTAATCAAGTATACAGACTTGTGTCAGAGAGACAGTTTGAAGTTGCCAATGTGGACGAATCATTAACAGGTGATGT
GGTTGTTGTTCGACCGACTCATTTATCTATTTGTGCGGCAGATCAACGTTACTATACAGGTTCTAGAGGGAAAGAAATGT
TATCTAAAAAACTTCCAATGGCGCTTATTCATGAAGGTGTTGGGGAAGTTGTTTATGATGCAACGAAAGAATTTAAACCA
GGTGCAAAAGTTGTCATGATTCCAAATACACCATTTGAGAATGATCCAGTCATTGCTGAGAACTATTTACGTTCGAGTAA
ATTCCGTTCTAGTGGTTATGATGGTTTAATGCAGGATTATGTGTTCATGCGTCGTGATCGTGTGGTGGCACTGCCGGATG
ATATTAACATGAAAGTAGCTGCTTTCTCAGAACTGATTTCCGTGGCAGTTCACGCTATTTTACGCTTTGAAGGTAAAAGT
AATGCTAACCGGGAATCTTTCGGTGTGTGGGGTGATGGGAACTTAGGTTTTATCACTTCTTTACTACTAAAAAATTGGTA
CCCTGATAGCAAAGTTTACATTTTTGGGAAAACACCATATAAATTAGACTTCTTTTCTTTTGTGGATGGTGCTTATGCAA
TTGATGATGTTCCGGCTGATTTAGTTATTGATCAAGCATTCGAATGTGCTGGAGGAATGGGTAGTCAGTATGCGGTGAGT
CAAATTATTGATGTCATTAAACCAGAAGGAACCATTTCCTTACTTGGTGTTTCGGAGTATCCGATTGAATTTAATTCACG
TATGGTACTTGAAAAAGGACTAACCGTTTATGGAAGTAGTCGTAGCGGTCGTGTTGATTTTGAGAAAACAGTGGAGTTCT
TATCAACCAATAAACGTGGGGTAGAATATCTGCAAAATCTTGTTGGGGAAGTTCATACAGTTCATTCCATTCAAGATGTA
ATCGAAGCGTTTGAAGCTGATTTACGCAGTCCATGGGGCAAGAGCGTTATGGAGTGGAAGATATAA

Upstream 100 bases:

>100_bases
GATGATGTGAAATTAGTTAAAGGTGAAATTTTCAACATTAAGATTACGACGCCTTATGATTTGAAAGTAGCGAATGCGAT
TATTCAGGAGCGGATAGCCA

Downstream 100 bases:

>100_bases
TAAAACATTGGGGAGTTTAGGCTGTATGCTAATGAATTTGTTTGCTAAAGTATTTTAGGAAGCAAGAAAATCGAATGTAA
GTATTCGATGGTCATTTGCT

Product: glucitol dehydrogenase

Products: NA

Alternate protein names: Ribulose-5-P reductase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MINQVYRLVSERQFEVANVDESLTGDVVVVRPTHLSICAADQRYYTGSRGKEMLSKKLPMALIHEGVGEVVYDATKEFKP
GAKVVMIPNTPFENDPVIAENYLRSSKFRSSGYDGLMQDYVFMRRDRVVALPDDINMKVAAFSELISVAVHAILRFEGKS
NANRESFGVWGDGNLGFITSLLLKNWYPDSKVYIFGKTPYKLDFFSFVDGAYAIDDVPADLVIDQAFECAGGMGSQYAVS
QIIDVIKPEGTISLLGVSEYPIEFNSRMVLEKGLTVYGSSRSGRVDFEKTVEFLSTNKRGVEYLQNLVGEVHTVHSIQDV
IEAFEADLRSPWGKSVMEWKI

Sequences:

>Translated_341_residues
MINQVYRLVSERQFEVANVDESLTGDVVVVRPTHLSICAADQRYYTGSRGKEMLSKKLPMALIHEGVGEVVYDATKEFKP
GAKVVMIPNTPFENDPVIAENYLRSSKFRSSGYDGLMQDYVFMRRDRVVALPDDINMKVAAFSELISVAVHAILRFEGKS
NANRESFGVWGDGNLGFITSLLLKNWYPDSKVYIFGKTPYKLDFFSFVDGAYAIDDVPADLVIDQAFECAGGMGSQYAVS
QIIDVIKPEGTISLLGVSEYPIEFNSRMVLEKGLTVYGSSRSGRVDFEKTVEFLSTNKRGVEYLQNLVGEVHTVHSIQDV
IEAFEADLRSPWGKSVMEWKI
>Mature_341_residues
MINQVYRLVSERQFEVANVDESLTGDVVVVRPTHLSICAADQRYYTGSRGKEMLSKKLPMALIHEGVGEVVYDATKEFKP
GAKVVMIPNTPFENDPVIAENYLRSSKFRSSGYDGLMQDYVFMRRDRVVALPDDINMKVAAFSELISVAVHAILRFEGKS
NANRESFGVWGDGNLGFITSLLLKNWYPDSKVYIFGKTPYKLDFFSFVDGAYAIDDVPADLVIDQAFECAGGMGSQYAVS
QIIDVIKPEGTISLLGVSEYPIEFNSRMVLEKGLTVYGSSRSGRVDFEKTVEFLSTNKRGVEYLQNLVGEVHTVHSIQDV
IEAFEADLRSPWGKSVMEWKI

Specific function: Catalyzes the conversion of ribulose 5-P to ribitol 5-P (Potential) [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323099, Length=338, Percent_Identity=26.9230769230769, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.137 [H]

Molecular weight: Translated: 38171; Mature: 38171

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINQVYRLVSERQFEVANVDESLTGDVVVVRPTHLSICAADQRYYTGSRGKEMLSKKLPM
CHHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCEEEEECCCCEECCCHHHHHHHHHCCH
ALIHEGVGEVVYDATKEFKPGAKVVMIPNTPFENDPVIAENYLRSSKFRSSGYDGLMQDY
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
VFMRRDRVVALPDDINMKVAAFSELISVAVHAILRFEGKSNANRESFGVWGDGNLGFITS
HHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
LLLKNWYPDSKVYIFGKTPYKLDFFSFVDGAYAIDDVPADLVIDQAFECAGGMGSQYAVS
HHHHHCCCCCEEEEEECCCCEEEHHHHHCCCCEECCCCHHHHHHHHHHHCCCCCCHHHHH
QIIDVIKPEGTISLLGVSEYPIEFNSRMVLEKGLTVYGSSRSGRVDFEKTVEFLSTNKRG
HHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECCCCCCCCHHHHHHHHHCCCHH
VEYLQNLVGEVHTVHSIQDVIEAFEADLRSPWGKSVMEWKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCC
>Mature Secondary Structure
MINQVYRLVSERQFEVANVDESLTGDVVVVRPTHLSICAADQRYYTGSRGKEMLSKKLPM
CHHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCEEEEECCCCEECCCHHHHHHHHHCCH
ALIHEGVGEVVYDATKEFKPGAKVVMIPNTPFENDPVIAENYLRSSKFRSSGYDGLMQDY
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
VFMRRDRVVALPDDINMKVAAFSELISVAVHAILRFEGKSNANRESFGVWGDGNLGFITS
HHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
LLLKNWYPDSKVYIFGKTPYKLDFFSFVDGAYAIDDVPADLVIDQAFECAGGMGSQYAVS
HHHHHCCCCCEEEEEECCCCEEEHHHHHCCCCEECCCCHHHHHHHHHHHCCCCCCHHHHH
QIIDVIKPEGTISLLGVSEYPIEFNSRMVLEKGLTVYGSSRSGRVDFEKTVEFLSTNKRG
HHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECCCCCCCCHHHHHHHHHCCCHH
VEYLQNLVGEVHTVHSIQDVIEAFEADLRSPWGKSVMEWKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11882717 [H]