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The map label for this gene is moaB [H]

Identifier: 226223666

GI number: 226223666

Start: 1076398

End: 1076886

Strand: Reverse

Name: moaB [H]

Synonym: Lm4b_01068

Alternate gene names: 226223666

Gene position: 1076886-1076398 (Counterclockwise)

Preceding gene: 226223667

Following gene: 226223658

Centisome position: 36.97

GC content: 41.31

Gene sequence:

>489_bases
ATGGAACAAAAAACATTTATTAAGGTAACTTGTAGTATTTTAACGATTAGTGATACAAGGAATTTGGATACGGATACTAG
TGGTCAACTGATTCACTCTGCCTTAGAAACTGCTGGGCATGAGGTTATTTCGCGGATTGTCGTGCCTGATGATGTTACGC
TCATTAAGCAAAAAATAAACGAGTTAGCAGCTAATGGGTCCTTTTGCCTTATCACAAATGGTGGTACCGGTATTGCTAGG
CGTGATGTTACGTATGAAGCATTATTCGCAACGATTCAGCAAGAAATCCCTGGGTTTGGTGAAATTTTCAGGATGCTCAG
TTACGAAGAAGTTGGTAGTCGCGCCATGGTGTCTCGTGCATTCGCTGGCTTTTCAGAAAGCGGCTTACTGCTTTTTGCGT
TGCCTGGATCAAGTAACGCTTGCCAGCTCGCTGTTCAAAAATTGATTATCCCAGAATTACCTCATTTAATAGCAGAACGA
CAAAAATAA

Upstream 100 bases:

>100_bases
TTGTTATTTTCAAAAATGGACGCGTGTTACTTCATGGGACAGAAAATATAACAGAAGCGAAAAAAACATATCACTTATTT
TTCAATTAAAGGAGGCAGTT

Downstream 100 bases:

>100_bases
AACATCCGACCACACATGTGACCGGATGTTTTATTTATCCTCCAATTTGACTCATACGCCGCCAAGTTGGTTTATTAGAT
TGTACTTCATCTTGTAATTT

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MEQKTFIKVTCSILTISDTRNLDTDTSGQLIHSALETAGHEVISRIVVPDDVTLIKQKINELAANGSFCLITNGGTGIAR
RDVTYEALFATIQQEIPGFGEIFRMLSYEEVGSRAMVSRAFAGFSESGLLLFALPGSSNACQLAVQKLIIPELPHLIAER
QK

Sequences:

>Translated_162_residues
MEQKTFIKVTCSILTISDTRNLDTDTSGQLIHSALETAGHEVISRIVVPDDVTLIKQKINELAANGSFCLITNGGTGIAR
RDVTYEALFATIQQEIPGFGEIFRMLSYEEVGSRAMVSRAFAGFSESGLLLFALPGSSNACQLAVQKLIIPELPHLIAER
QK
>Mature_162_residues
MEQKTFIKVTCSILTISDTRNLDTDTSGQLIHSALETAGHEVISRIVVPDDVTLIKQKINELAANGSFCLITNGGTGIAR
RDVTYEALFATIQQEIPGFGEIFRMLSYEEVGSRAMVSRAFAGFSESGLLLFALPGSSNACQLAVQKLIIPELPHLIAER
QK

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=156, Percent_Identity=34.6153846153846, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI10880983, Length=156, Percent_Identity=34.6153846153846, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787000, Length=149, Percent_Identity=37.5838926174497, Blast_Score=114, Evalue=4e-27,
Organism=Drosophila melanogaster, GI17136978, Length=158, Percent_Identity=33.5443037974684, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24638841, Length=158, Percent_Identity=33.5443037974684, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 17628; Mature: 17628

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQKTFIKVTCSILTISDTRNLDTDTSGQLIHSALETAGHEVISRIVVPDDVTLIKQKIN
CCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ELAANGSFCLITNGGTGIARRDVTYEALFATIQQEIPGFGEIFRMLSYEEVGSRAMVSRA
HHHCCCCEEEEECCCCCCEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FAGFSESGLLLFALPGSSNACQLAVQKLIIPELPHLIAERQK
HCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEQKTFIKVTCSILTISDTRNLDTDTSGQLIHSALETAGHEVISRIVVPDDVTLIKQKIN
CCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ELAANGSFCLITNGGTGIARRDVTYEALFATIQQEIPGFGEIFRMLSYEEVGSRAMVSRA
HHHCCCCEEEEECCCCCCEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FAGFSESGLLLFALPGSSNACQLAVQKLIIPELPHLIAERQK
HCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]