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The map label for this gene is rpiA

Identifier: 226223593

GI number: 226223593

Start: 1008017

End: 1008691

Strand: Direct

Name: rpiA

Synonym: Lm4b_00995

Alternate gene names: 226223593

Gene position: 1008017-1008691 (Clockwise)

Preceding gene: 226223588

Following gene: 226223596

Centisome position: 34.61

GC content: 36.59

Gene sequence:

>675_bases
ATGATTAATCAAAAGAAGATAGCAGGAGAAAAGGCTTGTGAGTGGATTAAAGATGGAATGGTTGTGGGCCTTGGAACGGG
CAGTACAGTCTATTACACGATTGAAAAGCTTGGAGAAATGGTAAATAATGGTTTGCATATTACAGGGGTGGCAACTTCTG
AAGAAACAAGCAAACAAGCACAAAATTTAGGAATACCTTTGAAATCGCTAAATGACGTAGCGGAAATAGATATTACTATT
GATGGTGCTGATGAAATTGATACGGATTTTCAAGGAATAAAAGGTGGAGGAGGAGCACTATTACGTGAAAAAATGGTAGC
AAGTGCGAGTTTGAAAAACATTTGGGTTGTCAGTGAGGAGAAGCTTGTAAGAAACTTAGGGAAGTTTCCTTTGCCTATAG
AAGTAATACCTTTTGGTTGGAAGCAAATTGAGAGAACACTTGAAAAAGAGCATGTTCAAACAATTTTACGGAGACAATCT
TCAGGAGAAATCTATGTGACAAATAACGGGAACTATATTTTGGATATAGTAAATCAAACTTTTAGGGATGCAGAAATGTG
GCAAGAAAAATTAGCGCAAATTCCAGGGATTGTGGAGCATGGATTATTTCTTCATTATGTGGATATAATTGTTTGTGCGA
AGGCAAATGGCGAAATAGAGCTAATAAAAAAATAG

Upstream 100 bases:

>100_bases
AAGGTTAGGAAAATATGCATATTTTGAACTTGAAAGTAGGTACGAGTATAATGAAACAATAGATATAGTAATGTTTTAAT
GCTAGAAAAGAGGTTGGAAT

Downstream 100 bases:

>100_bases
TTATTTCTTCTATATAAAAGAAATAACTATTTTTATTAAATTTCCTATGTTAATGTTTTTTTCATTTCTTTATGTTCAAT
TCCAGCATCAAGGAACAATC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MINQKKIAGEKACEWIKDGMVVGLGTGSTVYYTIEKLGEMVNNGLHITGVATSEETSKQAQNLGIPLKSLNDVAEIDITI
DGADEIDTDFQGIKGGGGALLREKMVASASLKNIWVVSEEKLVRNLGKFPLPIEVIPFGWKQIERTLEKEHVQTILRRQS
SGEIYVTNNGNYILDIVNQTFRDAEMWQEKLAQIPGIVEHGLFLHYVDIIVCAKANGEIELIKK

Sequences:

>Translated_224_residues
MINQKKIAGEKACEWIKDGMVVGLGTGSTVYYTIEKLGEMVNNGLHITGVATSEETSKQAQNLGIPLKSLNDVAEIDITI
DGADEIDTDFQGIKGGGGALLREKMVASASLKNIWVVSEEKLVRNLGKFPLPIEVIPFGWKQIERTLEKEHVQTILRRQS
SGEIYVTNNGNYILDIVNQTFRDAEMWQEKLAQIPGIVEHGLFLHYVDIIVCAKANGEIELIKK
>Mature_224_residues
MINQKKIAGEKACEWIKDGMVVGLGTGSTVYYTIEKLGEMVNNGLHITGVATSEETSKQAQNLGIPLKSLNDVAEIDITI
DGADEIDTDFQGIKGGGGALLREKMVASASLKNIWVVSEEKLVRNLGKFPLPIEVIPFGWKQIERTLEKEHVQTILRRQS
SGEIYVTNNGNYILDIVNQTFRDAEMWQEKLAQIPGIVEHGLFLHYVDIIVCAKANGEIELIKK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=231, Percent_Identity=32.9004329004329, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1789280, Length=220, Percent_Identity=37.7272727272727, Blast_Score=133, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17551758, Length=234, Percent_Identity=38.034188034188, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6324669, Length=241, Percent_Identity=30.7053941908714, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281364072, Length=230, Percent_Identity=33.4782608695652, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_LISMC (C1L1P6)

Other databases:

- EMBL:   FM242711
- RefSeq:   YP_002757700.1
- ProteinModelPortal:   C1L1P6
- GeneID:   7703280
- GenomeReviews:   FM242711_GR
- KEGG:   lmc:Lm4b_00995
- OMA:   MVVIADA
- ProtClustDB:   PRK00702
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24809; Mature: 24809

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINQKKIAGEKACEWIKDGMVVGLGTGSTVYYTIEKLGEMVNNGLHITGVATSEETSKQA
CCCCHHCCHHHHHHHHHCCEEEEECCCCEEEEEHHHHHHHHHCCEEEEEEECCHHHHHHH
QNLGIPLKSLNDVAEIDITIDGADEIDTDFQGIKGGGGALLREKMVASASLKNIWVVSEE
HHCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECHH
KLVRNLGKFPLPIEVIPFGWKQIERTLEKEHVQTILRRQSSGEIYVTNNGNYILDIVNQT
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEHHHH
FRDAEMWQEKLAQIPGIVEHGLFLHYVDIIVCAKANGEIELIKK
HHHHHHHHHHHHHCCCHHHHHHHHHEEHHHEEECCCCCEEEEEC
>Mature Secondary Structure
MINQKKIAGEKACEWIKDGMVVGLGTGSTVYYTIEKLGEMVNNGLHITGVATSEETSKQA
CCCCHHCCHHHHHHHHHCCEEEEECCCCEEEEEHHHHHHHHHCCEEEEEEECCHHHHHHH
QNLGIPLKSLNDVAEIDITIDGADEIDTDFQGIKGGGGALLREKMVASASLKNIWVVSEE
HHCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECHH
KLVRNLGKFPLPIEVIPFGWKQIERTLEKEHVQTILRRQSSGEIYVTNNGNYILDIVNQT
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEHHHH
FRDAEMWQEKLAQIPGIVEHGLFLHYVDIIVCAKANGEIELIKK
HHHHHHHHHHHHHCCCHHHHHHHHHEEHHHEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA