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The map label for this gene is nagA [H]

Identifier: 226223574

GI number: 226223574

Start: 990152

End: 991285

Strand: Direct

Name: nagA [H]

Synonym: Lm4b_00976

Alternate gene names: 226223574

Gene position: 990152-991285 (Clockwise)

Preceding gene: 226223573

Following gene: 226223575

Centisome position: 33.99

GC content: 38.54

Gene sequence:

>1134_bases
ATGACTAATAAAGTAATTACTAACGCTACAATTTATACTGGTAAAGGTGTTCTAGAAAATGCTTTCGTACGTTTTGACAA
ACAAATTTTAGAGGTTGGCTCGATGGCTGATTTCCAAGCGGACAAAGCAGAAGAAGTAATCGATGCCAAAGGACAAAAAC
TTGTTCCAGGTTTCATTGATGTTCATTCCCACGGTGGTTATAGTTTTGACGCAATGGATGCAGATCCAGAAGCACTTAGA
AAACAAGTGAACGGAATGTTAAATGAAGGAATTACTACTTACTTCCCAACAACGATGACACAATCACATGAAAATATTGA
AAAAGCATTAAAAGTGATCAATGAGGTTGCTCAAACAGAACCTGTTATTGGTGGAATTCATTTGGAAGGTCCATTTGTTT
CTAAAGTCTTTAAAGGCGCACAACCAGAAGAATATATTCAAGCACCTGACTTGGAACTTTTCAAAAAGTGGTTTGATATT
TCTGGTGGTTTAATTAAATTAGTCACCTATGCACCAGAACACGATACTTCAGCTGATTTTGAAAATTTGTGTTTTGAACT
AGGGGTTGTTCCGAGTATTGGTCACTCTAATGATGTTCGTGAGCACTTGAAAACAAGTAAAGCGACACACGCGACACATT
TATATAATGCTTGTCACCGTATGACGCACCGTGAGCCAGGCGTTCCAGGTCATGTTTTACTAGAACGCGGTATTAATGCA
GAACTAATCGTTGATGGTATTCACGTTCATCCTGATATGGTGAAATTAGCTTATCAAATGAAAGGGCCAGAACATTTATG
CATTATCACTGACTCCATGCGAGCAAAAGGTATGCCAGAAGGGAAATCTGAACTTGGCGGCCAAACTGTTATCGTGAAAG
ATAAACAAGCTCGTTTAGAAGATGGAACTTTAGCTGGAAGTGTACTCACTTATGACGATGGCTTCCGCAACATGATTAAA
TTTACTGGATGCTCGGTAGAAGAGGCAGTTCTTATGTCTTCTGGAAACCAAGCACGCGAATTTAATTTAACACAAAAAGG
TGCAATCGAGGCTGGTAAGGATGCAGATTTCAACTTACTTGACGAAGATTTACACATTACAGCAACTTATTCATTCGGAA
AAAAACATTCTTGA

Upstream 100 bases:

>100_bases
ATTACTTTTTTTCGGGTAAATAGGAAAAGATAAGTTGCATTTTAATAGATACGTGCTATAATAATTGGTATAGACCGATT
TAACAAGGAGGCAATATGTA

Downstream 100 bases:

>100_bases
GAGGAAGATAATAAAATGCAACTTATCACAACAGAAAACAAATTAGCAGGATCCAAAAAAGCCTTAGAAATCATTGAAAA
AGGCATTACATCAGGTGAAG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTNKVITNATIYTGKGVLENAFVRFDKQILEVGSMADFQADKAEEVIDAKGQKLVPGFIDVHSHGGYSFDAMDADPEALR
KQVNGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTEPVIGGIHLEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDI
SGGLIKLVTYAPEHDTSADFENLCFELGVVPSIGHSNDVREHLKTSKATHATHLYNACHRMTHREPGVPGHVLLERGINA
ELIVDGIHVHPDMVKLAYQMKGPEHLCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLEDGTLAGSVLTYDDGFRNMIK
FTGCSVEEAVLMSSGNQAREFNLTQKGAIEAGKDADFNLLDEDLHITATYSFGKKHS

Sequences:

>Translated_377_residues
MTNKVITNATIYTGKGVLENAFVRFDKQILEVGSMADFQADKAEEVIDAKGQKLVPGFIDVHSHGGYSFDAMDADPEALR
KQVNGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTEPVIGGIHLEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDI
SGGLIKLVTYAPEHDTSADFENLCFELGVVPSIGHSNDVREHLKTSKATHATHLYNACHRMTHREPGVPGHVLLERGINA
ELIVDGIHVHPDMVKLAYQMKGPEHLCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLEDGTLAGSVLTYDDGFRNMIK
FTGCSVEEAVLMSSGNQAREFNLTQKGAIEAGKDADFNLLDEDLHITATYSFGKKHS
>Mature_376_residues
TNKVITNATIYTGKGVLENAFVRFDKQILEVGSMADFQADKAEEVIDAKGQKLVPGFIDVHSHGGYSFDAMDADPEALRK
QVNGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTEPVIGGIHLEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDIS
GGLIKLVTYAPEHDTSADFENLCFELGVVPSIGHSNDVREHLKTSKATHATHLYNACHRMTHREPGVPGHVLLERGINAE
LIVDGIHVHPDMVKLAYQMKGPEHLCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLEDGTLAGSVLTYDDGFRNMIKF
TGCSVEEAVLMSSGNQAREFNLTQKGAIEAGKDADFNLLDEDLHITATYSFGKKHS

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=418, Percent_Identity=30.8612440191388, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI224922791, Length=417, Percent_Identity=30.9352517985612, Blast_Score=155, Evalue=7e-38,
Organism=Escherichia coli, GI1786892, Length=383, Percent_Identity=32.3759791122715, Blast_Score=159, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17553768, Length=382, Percent_Identity=31.413612565445, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI19920392, Length=350, Percent_Identity=33.4285714285714, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI281361140, Length=361, Percent_Identity=32.1329639889197, Blast_Score=154, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41444; Mature: 41313

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKVITNATIYTGKGVLENAFVRFDKQILEVGSMADFQADKAEEVIDAKGQKLVPGFID
CCCCEEECEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEECCCEEE
VHSHGGYSFDAMDADPEALRKQVNGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTE
EECCCCEEECCCCCCHHHHHHHHHHHHHCCCCEECCCHHHCCHHHHHHHHHHHHHHHHCC
PVIGGIHLEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDISGGLIKLVTYAPEHDTSADF
CCEEEEEECCHHHHHHHCCCCCHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCH
ENLCFELGVVPSIGHSNDVREHLKTSKATHATHLYNACHRMTHREPGVPGHVLLERGINA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
ELIVDGIHVHPDMVKLAYQMKGPEHLCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLE
EEEEECEECCHHHHHHHHHCCCCCEEEEEECCHHCCCCCCCHHHCCCCEEEEECCHHCCC
DGTLAGSVLTYDDGFRNMIKFTGCSVEEAVLMSSGNQAREFNLTQKGAIEAGKDADFNLL
CCCEECEEEEECCHHHHHHHHCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEE
DEDLHITATYSFGKKHS
CCCEEEEEEECCCCCCC
>Mature Secondary Structure 
TNKVITNATIYTGKGVLENAFVRFDKQILEVGSMADFQADKAEEVIDAKGQKLVPGFID
CCCEEECEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEECCCEEE
VHSHGGYSFDAMDADPEALRKQVNGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTE
EECCCCEEECCCCCCHHHHHHHHHHHHHCCCCEECCCHHHCCHHHHHHHHHHHHHHHHCC
PVIGGIHLEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDISGGLIKLVTYAPEHDTSADF
CCEEEEEECCHHHHHHHCCCCCHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCH
ENLCFELGVVPSIGHSNDVREHLKTSKATHATHLYNACHRMTHREPGVPGHVLLERGINA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
ELIVDGIHVHPDMVKLAYQMKGPEHLCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLE
EEEEECEECCHHHHHHHHHCCCCCEEEEEECCHHCCCCCCCHHHCCCCEEEEECCHHCCC
DGTLAGSVLTYDDGFRNMIKFTGCSVEEAVLMSSGNQAREFNLTQKGAIEAGKDADFNLL
CCCEECEEEEECCHHHHHHHHCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEE
DEDLHITATYSFGKKHS
CCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA