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The map label for this gene is coaA [H]

Identifier: 226223542

GI number: 226223542

Start: 960833

End: 961753

Strand: Direct

Name: coaA [H]

Synonym: Lm4b_00942

Alternate gene names: 226223542

Gene position: 960833-961753 (Clockwise)

Preceding gene: 226223541

Following gene: 226223543

Centisome position: 32.99

GC content: 37.68

Gene sequence:

>921_bases
ATGAATGATTACAACCACTACTTTCATTTCCCACGAGAAGAATGGCGCAAGCTGGAAGTGAGTAAGGACCAAATTTTAAC
TGCAGAGGAACTGGAAGAAATACGTGGTTTAAATGACCGAATTTCTTTACAAGACATCTCTGAAATCTATTTACCACTAA
TAAAACTAATTGCGATTCAATACCATGAAGCGATTTTTATTCATGGCGAAAAAATGGAATACTTAAAGAAAAAAGAATCG
CGAGCACCATTTATTATTGCATTAGCAGGAAGTGTGGCTGTTGGGAAAAGTACGACAGCACGTGTTTTCAAATTAATGCT
TGATCGCTGGTTCTCCAAAACTAGACAAGTAGAGCTTGTGACGACAGACGGCTTTCTTTATCCTAACAAAGTTTTAGAAG
AGCGCGGTATCATGGACAAAAAAGGCTTCCCTGAAAGCTACGACCGCGACCGTTTTGCCAAGTTTTTAACCGACTTAAAA
GCAAATAAAGAAGATGTCGAAATTCCACTTTATTCGCATTTCACTTATGATGTTTTAGACGAAACCCGTGTGATCCATAA
TCCAGATATCGTCATCATTGAAGGAATCAATGTTCTTCAAGCAGATCAACATGAGAGCCTGTTTCCAAGTGACTTCTTTG
ATTTTTCCGTTTACATGGATGCCAATGAAGCGGATATTAAGAAATGGTATTTAGAACGTTTCTTCATGCTTCGCGAAACA
GCTTTCCAAGATGAAAGTTCTTATTTCCACCCATATACTAAAATTAGCAAACAAGAAGCAGAAACATTTGCACTCGGGGT
TTGGGATACAATCAACGGCGTCAACTTAAAAGAAAACATTGAGAAAACAAAATATCGAGCCGACTTAGTGCTTCAAAAAG
GCACAGATCATCTCATTTCAGACATTTATTTACGCAAATAA

Upstream 100 bases:

>100_bases
CGTAAATATTAAATCGCTACTTGCGGATTTATGCAGCTTGCGTTATCCTTAAATAAAGCTGTTTACGTTTTCACGAATGA
ATAAAAGGATGGAACATTGA

Downstream 100 bases:

>100_bases
CCGAATGCAGATAGAAGGAAACTTCTTGATGCATTCGGTTTTTTCTTTACATTGGAGAAAATCCGAGTACAATAGAAAGT
GAGTAATCACTCATTTGAAA

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQYHEAIFIHGEKMEYLKKKES
RAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELVTTDGFLYPNKVLEERGIMDKKGFPESYDRDRFAKFLTDLK
ANKEDVEIPLYSHFTYDVLDETRVIHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDANEADIKKWYLERFFMLRET
AFQDESSYFHPYTKISKQEAETFALGVWDTINGVNLKENIEKTKYRADLVLQKGTDHLISDIYLRK

Sequences:

>Translated_306_residues
MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQYHEAIFIHGEKMEYLKKKES
RAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELVTTDGFLYPNKVLEERGIMDKKGFPESYDRDRFAKFLTDLK
ANKEDVEIPLYSHFTYDVLDETRVIHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDANEADIKKWYLERFFMLRET
AFQDESSYFHPYTKISKQEAETFALGVWDTINGVNLKENIEKTKYRADLVLQKGTDHLISDIYLRK
>Mature_306_residues
MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQYHEAIFIHGEKMEYLKKKES
RAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELVTTDGFLYPNKVLEERGIMDKKGFPESYDRDRFAKFLTDLK
ANKEDVEIPLYSHFTYDVLDETRVIHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDANEADIKKWYLERFFMLRET
AFQDESSYFHPYTKISKQEAETFALGVWDTINGVNLKENIEKTKYRADLVLQKGTDHLISDIYLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=307, Percent_Identity=46.5798045602606, Blast_Score=286, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 36110; Mature: 36110

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQ
CCCCCCCCCCCHHHHHEECCCHHHEECHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YHEAIFIHGEKMEYLKKKESRAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELV
HHCEEEEECCHHHHHHHHCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCEEEEE
TTDGFLYPNKVLEERGIMDKKGFPESYDRDRFAKFLTDLKANKEDVEIPLYSHFTYDVLD
EECCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
ETRVIHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDANEADIKKWYLERFFMLRET
CCEEEECCCEEEECCCCEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
AFQDESSYFHPYTKISKQEAETFALGVWDTINGVNLKENIEKTKYRADLVLQKGTDHLIS
HCCCCCCCCCCHHHHHHHHHHEEEEEEHHCCCCCCHHHHHHHHHHHHHHEEECCCHHHHH
DIYLRK
HHHCCC
>Mature Secondary Structure
MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQ
CCCCCCCCCCCHHHHHEECCCHHHEECHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YHEAIFIHGEKMEYLKKKESRAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELV
HHCEEEEECCHHHHHHHHCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCEEEEE
TTDGFLYPNKVLEERGIMDKKGFPESYDRDRFAKFLTDLKANKEDVEIPLYSHFTYDVLD
EECCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
ETRVIHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDANEADIKKWYLERFFMLRET
CCEEEECCCEEEECCCCEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
AFQDESSYFHPYTKISKQEAETFALGVWDTINGVNLKENIEKTKYRADLVLQKGTDHLIS
HCCCCCCCCCCHHHHHHHHHHEEEEEEHHCCCCCCHHHHHHHHHHHHHHEEECCCHHHHH
DIYLRK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]