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The map label for this gene is bglH [H]

Identifier: 226223537

GI number: 226223537

Start: 953439

End: 954890

Strand: Direct

Name: bglH [H]

Synonym: Lm4b_00937

Alternate gene names: 226223537

Gene position: 953439-954890 (Clockwise)

Preceding gene: 226223536

Following gene: 226223538

Centisome position: 32.73

GC content: 37.81

Gene sequence:

>1452_bases
ATGTTTGAAAATTATCAATTTCCAAAAGACTTTTTATGGGGAGGAGCTATCGCAGCCAACCAAGCAGAAGGCGCATTTAA
AGTAGATGGAAAAGGAATTAGTTTAGCAGATTTGCACAAATATCATAAAGGGAAAACAAATGATGAAATCAGTGAGGAAC
AACATAAAGGAGTAAGTTTGGCTGATATCAAAGCAAGTATGGAAGACAAAGTGAACTATTATCCGAAACGCCACGGTATC
GACTTTTATCACACGTATCCAGAAGATTTGGCTTTGCTTGCTGAAATGGGCTTTAAAACATTTCGAACTTCGCTGGACTG
GACACGGATTTTTCCAACTGGCGAAGAAACAGAACCAAATGAAGCGGGATTAAAATATTATGACCAATTAATTGATAAAA
TTATCGAACTTGGCATGGAGCCAATTATTACGATTTTACATTACGAAACGCCGGTGGAAATTGTCTTAAATCACGGCGGT
TGGCATAATCGTAAAGTTATTGATTTATTTGAGAAGTACGGCAAAACGGTACTTGATCGCTACAATAAAAAAGTAAAATA
TTGGATTATCATTAACCAAATTAATTTAATTCAATTCGAACCATTTAACTCTACTGCGATTCCATATGATGCCGTCGATG
ATTATTTATCCGCTACGTATCAAGCTGTTCATAACCAATTTGTTGCAAGTGCGAAAATTTACGAATACGGAAAAGCGCTA
AATCCTGATTTAATGATTGGTACAATGCTCGCTGATTGCACGGCCTATCCATTCTCCTGCGATCCAGATGATATCGTGCT
CGCAATGAAACGCAACCGCATGGAATATTTCTTCGCAGACGTGCAGTTCCAAGGCGAATATCCACAGTATGCGCTTAATT
ACTTTGACGAAAATAATATTCATATAGAAATCACAGAAGACGACAAAGCCGTTTTACAAAAAAACACCATGGATTATTTA
GCACTTTCCTATTATTATTCCCAAATGGTGGACTCCAAGAAAAATGATTTGGACCCAGCTTCAATTACACCAAACCCGCA
TCTTAAAGCTAATCCGTGGGGCTGGGCAGTCGATCCGAAAGGCTTGTATAACGCATTGTCGCAGTACTGGGACAGATATC
ATAAACCAATTATCATTGCCGAAAATGGTTTTGGAATGTATGACAAATTAGAAAATGGCGAAATCCATGATGATTACCGG
ATTGATTATTTATCCGCGCATCTAAAAGAAATGAAACGCGCCATGTATGACGGCGTAGAAATTATCGCATATTGCGCTTG
GGGACCGATTGATATAGTTAGTTGCTCCTCCGCACAAATGGAAAAAAGATACGGTTTCATTTACGTTGATTTAGATAACG
AAGGAAACGGTACAGGCAAAAGAATTAAAAAAGACAGCTTTTCATGGTATAAAAAAGTAATAGAGTCTAATGGGGAAGAC
TTAGAAGCTTAA

Upstream 100 bases:

>100_bases
ATACACTCATGACAGCCAAAAGTGAAATATTAATCGGCGAGCATATGCTACGTTTATTCAAAAAAATGACCGAACTTACG
AAAAAATAGGAGGTACGAGC

Downstream 100 bases:

>100_bases
TGTAACAGAGCGCCAGTTGTGGTAGTTGATAGCTAATACAACTGGCTTTCGATATATAGGGGGTAACAAAAAATGGATAC
TCAAAAAGAAATACTAGCTT

Product: beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MFENYQFPKDFLWGGAIAANQAEGAFKVDGKGISLADLHKYHKGKTNDEISEEQHKGVSLADIKASMEDKVNYYPKRHGI
DFYHTYPEDLALLAEMGFKTFRTSLDWTRIFPTGEETEPNEAGLKYYDQLIDKIIELGMEPIITILHYETPVEIVLNHGG
WHNRKVIDLFEKYGKTVLDRYNKKVKYWIIINQINLIQFEPFNSTAIPYDAVDDYLSATYQAVHNQFVASAKIYEYGKAL
NPDLMIGTMLADCTAYPFSCDPDDIVLAMKRNRMEYFFADVQFQGEYPQYALNYFDENNIHIEITEDDKAVLQKNTMDYL
ALSYYYSQMVDSKKNDLDPASITPNPHLKANPWGWAVDPKGLYNALSQYWDRYHKPIIIAENGFGMYDKLENGEIHDDYR
IDYLSAHLKEMKRAMYDGVEIIAYCAWGPIDIVSCSSAQMEKRYGFIYVDLDNEGNGTGKRIKKDSFSWYKKVIESNGED
LEA

Sequences:

>Translated_483_residues
MFENYQFPKDFLWGGAIAANQAEGAFKVDGKGISLADLHKYHKGKTNDEISEEQHKGVSLADIKASMEDKVNYYPKRHGI
DFYHTYPEDLALLAEMGFKTFRTSLDWTRIFPTGEETEPNEAGLKYYDQLIDKIIELGMEPIITILHYETPVEIVLNHGG
WHNRKVIDLFEKYGKTVLDRYNKKVKYWIIINQINLIQFEPFNSTAIPYDAVDDYLSATYQAVHNQFVASAKIYEYGKAL
NPDLMIGTMLADCTAYPFSCDPDDIVLAMKRNRMEYFFADVQFQGEYPQYALNYFDENNIHIEITEDDKAVLQKNTMDYL
ALSYYYSQMVDSKKNDLDPASITPNPHLKANPWGWAVDPKGLYNALSQYWDRYHKPIIIAENGFGMYDKLENGEIHDDYR
IDYLSAHLKEMKRAMYDGVEIIAYCAWGPIDIVSCSSAQMEKRYGFIYVDLDNEGNGTGKRIKKDSFSWYKKVIESNGED
LEA
>Mature_483_residues
MFENYQFPKDFLWGGAIAANQAEGAFKVDGKGISLADLHKYHKGKTNDEISEEQHKGVSLADIKASMEDKVNYYPKRHGI
DFYHTYPEDLALLAEMGFKTFRTSLDWTRIFPTGEETEPNEAGLKYYDQLIDKIIELGMEPIITILHYETPVEIVLNHGG
WHNRKVIDLFEKYGKTVLDRYNKKVKYWIIINQINLIQFEPFNSTAIPYDAVDDYLSATYQAVHNQFVASAKIYEYGKAL
NPDLMIGTMLADCTAYPFSCDPDDIVLAMKRNRMEYFFADVQFQGEYPQYALNYFDENNIHIEITEDDKAVLQKNTMDYL
ALSYYYSQMVDSKKNDLDPASITPNPHLKANPWGWAVDPKGLYNALSQYWDRYHKPIIIAENGFGMYDKLENGEIHDDYR
IDYLSAHLKEMKRAMYDGVEIIAYCAWGPIDIVSCSSAQMEKRYGFIYVDLDNEGNGTGKRIKKDSFSWYKKVIESNGED
LEA

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=501, Percent_Identity=26.7465069860279, Blast_Score=169, Evalue=8e-42,
Organism=Homo sapiens, GI32481206, Length=511, Percent_Identity=27.0058708414873, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI110681710, Length=502, Percent_Identity=27.6892430278884, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI28376633, Length=497, Percent_Identity=25.3521126760563, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI24497614, Length=482, Percent_Identity=25.9336099585062, Blast_Score=126, Evalue=5e-29,
Organism=Escherichia coli, GI2367270, Length=482, Percent_Identity=46.2655601659751, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI2367174, Length=486, Percent_Identity=44.4444444444444, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1789070, Length=483, Percent_Identity=41.2008281573499, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17539390, Length=476, Percent_Identity=25.8403361344538, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17552856, Length=496, Percent_Identity=25.8064516129032, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21356577, Length=509, Percent_Identity=26.7190569744597, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55805; Mature: 55805

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENYQFPKDFLWGGAIAANQAEGAFKVDGKGISLADLHKYHKGKTNDEISEEQHKGVSL
CCCCCCCCHHHHCCCCEECCCCCCCEEECCCCCCHHHHHHHHCCCCCCCHHHHHHCCCCH
ADIKASMEDKVNYYPKRHGIDFYHTYPEDLALLAEMGFKTFRTSLDWTRIFPTGEETEPN
HHHHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHCHHHHHCCCCEEEECCCCCCCCCC
EAGLKYYDQLIDKIIELGMEPIITILHYETPVEIVLNHGGWHNRKVIDLFEKYGKTVLDR
HHHHHHHHHHHHHHHHCCHHHEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
YNKKVKYWIIINQINLIQFEPFNSTAIPYDAVDDYLSATYQAVHNQFVASAKIYEYGKAL
CCCCEEEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPDLMIGTMLADCTAYPFSCDPDDIVLAMKRNRMEYFFADVQFQGEYPQYALNYFDENNI
CCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHCCEEEEEEEEEECCCCCHHHHHCCCCCCE
HIEITEDDKAVLQKNTMDYLALSYYYSQMVDSKKNDLDPASITPNPHLKANPWGWAVDPK
EEEEECCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
GLYNALSQYWDRYHKPIIIAENGFGMYDKLENGEIHDDYRIDYLSAHLKEMKRAMYDGVE
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCE
IIAYCAWGPIDIVSCSSAQMEKRYGFIYVDLDNEGNGTGKRIKKDSFSWYKKVIESNGED
EEEEECCCCEEEEECCCHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCC
LEA
CCC
>Mature Secondary Structure
MFENYQFPKDFLWGGAIAANQAEGAFKVDGKGISLADLHKYHKGKTNDEISEEQHKGVSL
CCCCCCCCHHHHCCCCEECCCCCCCEEECCCCCCHHHHHHHHCCCCCCCHHHHHHCCCCH
ADIKASMEDKVNYYPKRHGIDFYHTYPEDLALLAEMGFKTFRTSLDWTRIFPTGEETEPN
HHHHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHCHHHHHCCCCEEEECCCCCCCCCC
EAGLKYYDQLIDKIIELGMEPIITILHYETPVEIVLNHGGWHNRKVIDLFEKYGKTVLDR
HHHHHHHHHHHHHHHHCCHHHEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
YNKKVKYWIIINQINLIQFEPFNSTAIPYDAVDDYLSATYQAVHNQFVASAKIYEYGKAL
CCCCEEEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPDLMIGTMLADCTAYPFSCDPDDIVLAMKRNRMEYFFADVQFQGEYPQYALNYFDENNI
CCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHCCEEEEEEEEEECCCCCHHHHHCCCCCCE
HIEITEDDKAVLQKNTMDYLALSYYYSQMVDSKKNDLDPASITPNPHLKANPWGWAVDPK
EEEEECCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
GLYNALSQYWDRYHKPIIIAENGFGMYDKLENGEIHDDYRIDYLSAHLKEMKRAMYDGVE
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCE
IIAYCAWGPIDIVSCSSAQMEKRYGFIYVDLDNEGNGTGKRIKKDSFSWYKKVIESNGED
EEEEECCCCEEEEECCCHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCC
LEA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]