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The map label for this gene is yrpG [H]

Identifier: 226223497

GI number: 226223497

Start: 917518

End: 918471

Strand: Direct

Name: yrpG [H]

Synonym: Lm4b_00896

Alternate gene names: 226223497

Gene position: 917518-918471 (Clockwise)

Preceding gene: 226223496

Following gene: 226223498

Centisome position: 31.5

GC content: 44.34

Gene sequence:

>954_bases
ATGGAAAAAATTATCGTTAACGGCAGAAAAAATGGACAAAAAATCGAGATAGCTTGCTCTAATTTAGTGATGGGTGCAGG
AGATTTCTTACGTGCAGATAATATGGATTTTGCGGGTCCAGTACTAGATCAATATTTTGAAATGGGTGGAAATATTTTTG
ATACGGCGCGCCATTATCGCCATAGTGAAAAAGCGATTGGCGCGTGGATGAATATGAGAGGAAATCGTGATAGTGTCATT
ATCCAAACGAAAGGCGGGCATCCAGTTCGGGAAGCAAGCGACGTGCCGCGGGTTACTCCGGAAGCAATTCACGAAGATAT
TTCGGTTAGTTTAGATACGCTACAAACAGATCATGTTGAATTATTCGCACTTCATCGCGACAATCCAGATGTAGAAGTGG
GTCCTATTATGGAGGCGATGCATAAAGAAGTGGAAGATGGCCGCGTTTATGCTATCGGACTTTCAAACTGGGAGCTCCCG
CGTATTATCGAAGCGAATGAATATGCAGTGAGCCATGGATTGACGCCACTAAGCTTTAACAGCCCTAATTTTAGTTTGGC
AAAAGTGAATCGACCACGCTGGGAAAATTGTGTTTCGGCGAGTGAAGAGATGATTCGCTGGCATGAGGCGACGAATTTGC
CACTATTTTCTTGGTCATCACAAGCAGGCGGATTTTTCTCTGGTAGATTTTCTGAGGAAGACACGCGCGATACGGAAATG
GTCGAAGTTTATTATAGTGAGGCAAACTGGGAAAGATACAGTCGTGCCAAGCAACTAGCTAACCAAAAAGGTTGCACTCC
AATCCAAATTTCGCTTGCTTATGTATTAACGCAATCATTCCCGACAGCCGCTGTCATCGGTCCGGAAAATGCTACGGAAC
TTCAATCTTCCGTTGCAGCGGCCGGGATTAAATTAACAGCGTCTGAGGTTGATTGGCTGGATTTAAAGGCATAA

Upstream 100 bases:

>100_bases
TGGAAAAAGAACCGACAGTAGCGATTCCTGCAACACTCGTAAAAGATTCGAATACAACACTTGTAGTCGATAAAATTGCC
GCGAGTGGGGTGGAAGCATA

Downstream 100 bases:

>100_bases
GGAAAGGCGGAGAAACAATGAATATAAAAGAAAAAATAGCAGTCCAACTTTATTCTGTACGAAAAGAAATGGAGCGCGAT
TTAGAAGGTACGCTCCGGAA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MEKIIVNGRKNGQKIEIACSNLVMGAGDFLRADNMDFAGPVLDQYFEMGGNIFDTARHYRHSEKAIGAWMNMRGNRDSVI
IQTKGGHPVREASDVPRVTPEAIHEDISVSLDTLQTDHVELFALHRDNPDVEVGPIMEAMHKEVEDGRVYAIGLSNWELP
RIIEANEYAVSHGLTPLSFNSPNFSLAKVNRPRWENCVSASEEMIRWHEATNLPLFSWSSQAGGFFSGRFSEEDTRDTEM
VEVYYSEANWERYSRAKQLANQKGCTPIQISLAYVLTQSFPTAAVIGPENATELQSSVAAAGIKLTASEVDWLDLKA

Sequences:

>Translated_317_residues
MEKIIVNGRKNGQKIEIACSNLVMGAGDFLRADNMDFAGPVLDQYFEMGGNIFDTARHYRHSEKAIGAWMNMRGNRDSVI
IQTKGGHPVREASDVPRVTPEAIHEDISVSLDTLQTDHVELFALHRDNPDVEVGPIMEAMHKEVEDGRVYAIGLSNWELP
RIIEANEYAVSHGLTPLSFNSPNFSLAKVNRPRWENCVSASEEMIRWHEATNLPLFSWSSQAGGFFSGRFSEEDTRDTEM
VEVYYSEANWERYSRAKQLANQKGCTPIQISLAYVLTQSFPTAAVIGPENATELQSSVAAAGIKLTASEVDWLDLKA
>Mature_317_residues
MEKIIVNGRKNGQKIEIACSNLVMGAGDFLRADNMDFAGPVLDQYFEMGGNIFDTARHYRHSEKAIGAWMNMRGNRDSVI
IQTKGGHPVREASDVPRVTPEAIHEDISVSLDTLQTDHVELFALHRDNPDVEVGPIMEAMHKEVEDGRVYAIGLSNWELP
RIIEANEYAVSHGLTPLSFNSPNFSLAKVNRPRWENCVSASEEMIRWHEATNLPLFSWSSQAGGFFSGRFSEEDTRDTEM
VEVYYSEANWERYSRAKQLANQKGCTPIQISLAYVLTQSFPTAAVIGPENATELQSSVAAAGIKLTASEVDWLDLKA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=307, Percent_Identity=22.8013029315961, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI4504825, Length=307, Percent_Identity=22.8013029315961, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081735, Length=317, Percent_Identity=24.2902208201893, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323998, Length=325, Percent_Identity=26.4615384615385, Blast_Score=99, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=26.6447368421053, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319951, Length=324, Percent_Identity=24.3827160493827, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=259, Percent_Identity=23.5521235521236, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35367; Mature: 35367

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIIVNGRKNGQKIEIACSNLVMGAGDFLRADNMDFAGPVLDQYFEMGGNIFDTARHYR
CCEEEEECCCCCCEEEEEEECEEECCCCCEECCCCCCCHHHHHHHHHHCCCHHHHHHHHH
HSEKAIGAWMNMRGNRDSVIIQTKGGHPVREASDVPRVTPEAIHEDISVSLDTLQTDHVE
HHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHCCCCCCCHHHHHHHHHEEEEHCCCCCEE
LFALHRDNPDVEVGPIMEAMHKEVEDGRVYAIGLSNWELPRIIEANEYAVSHGLTPLSFN
EEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCHHHCCCCEEEEC
SPNFSLAKVNRPRWENCVSASEEMIRWHEATNLPLFSWSSQAGGFFSGRFSEEDTRDTEM
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEECCCCCCCCCCCCEE
VEVYYSEANWERYSRAKQLANQKGCTPIQISLAYVLTQSFPTAAVIGPENATELQSSVAA
EEEEECCCCHHHHHHHHHHHHHCCCCEEEEEHEEHHHCCCCCEEEECCCCHHHHHHHHHH
AGIKLTASEVDWLDLKA
CCEEEEECCCCEEECCC
>Mature Secondary Structure
MEKIIVNGRKNGQKIEIACSNLVMGAGDFLRADNMDFAGPVLDQYFEMGGNIFDTARHYR
CCEEEEECCCCCCEEEEEEECEEECCCCCEECCCCCCCHHHHHHHHHHCCCHHHHHHHHH
HSEKAIGAWMNMRGNRDSVIIQTKGGHPVREASDVPRVTPEAIHEDISVSLDTLQTDHVE
HHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHCCCCCCCHHHHHHHHHEEEEHCCCCCEE
LFALHRDNPDVEVGPIMEAMHKEVEDGRVYAIGLSNWELPRIIEANEYAVSHGLTPLSFN
EEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCHHHCCCCEEEEC
SPNFSLAKVNRPRWENCVSASEEMIRWHEATNLPLFSWSSQAGGFFSGRFSEEDTRDTEM
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEECCCCCCCCCCCCEE
VEVYYSEANWERYSRAKQLANQKGCTPIQISLAYVLTQSFPTAAVIGPENATELQSSVAA
EEEEECCCCHHHHHHHHHHHHHCCCCEEEEEHEEHHHCCCCCEEEECCCCHHHHHHHHHH
AGIKLTASEVDWLDLKA
CCEEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]