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The map label for this gene is licC [H]

Identifier: 226223495

GI number: 226223495

Start: 915444

End: 916769

Strand: Direct

Name: licC [H]

Synonym: Lm4b_00894

Alternate gene names: 226223495

Gene position: 915444-916769 (Clockwise)

Preceding gene: 226223494

Following gene: 226223496

Centisome position: 31.43

GC content: 39.89

Gene sequence:

>1326_bases
ATGTCGAGTAAAAACAAACAATCTTTTATGAACCGTTTTATTGCTTTTATGGAGAAATATTTTGAACCTGTCGCAGCTAG
AATTGAAAAACAACGTCATATTTCCTCAATAAAAAATGGGATGATTGCTTTGATCTCGGTTTTAATTATTGGATCATTTT
CGCTGATTATTTCAGCAATCGGAAATATGTTTCCAGCAGGTTCTGTTGTGAAAGAATTCTTTGTTCAAAATGCAGCAGCG
CTTAACTTACCGTTTCAATTTACGTTTGGATTACTATCGATTTATGCGGCTATAACAATTTCCTATAGCCACGCAAAACA
AATGAAAGTACCTGTGTTACATAGTGTGATGGCAGCTGTTATGGTGACGCTCATCCTCAATACGAAAATGGTTGACGGGG
TGCTTAATACAGAATTTCTGGATTCAAGAGGGCTATTTATCGCCATTTTTGCAGCGCTGATTTCTGTAGAACTTATCGGT
TTATTTATTAGAAAAAATATTACGATTCGAATTAAAGGGTTACCGGCGGGGATTGCGACTACTTTTGAAGCAATTATTCC
ACTAGTTGTACTGCTATTCAGTGCTGTTGGACTAAGTATTTTAATGCAAAGTGTCACTAGCGGTCAAATCATTCCGGAAG
CCTTTACGACGATGCTAGCTCCGGCGATTAATAGTATTGATACGCCTTATGCGGTTTTCCTTATTTGTTTCCTTGAAATG
CTATTCTGGTTTATCGGTCTAAATGGTTATGCGATTTTGATTGGTTTTGTGCTTCCATTTATGACACAATATTTAGGAGC
GAACGCGGCTGCATATGCGGCAGGAGAACCAATTCCGCACGTATTTGCGCCAAACTTCTGGGATTACTTCATGGGCTTCT
CTGGTTCTGGTATTACAGGTGCATTAGTTATCCTTGCGCTATTTAGTAAATCAAGAGAATTAAAAGCGGTCGGAAAAGTG
TCGGTTGTTCCAGCGATTTTCACAATTTCTGAACCAGTTGTATTCGGTTTGCCAATCTGTTTTAATCCGTATTTGTTTAT
TCCATTCGTACTTGGAACGCCAATTTTAGCAGTAGGGCAATGGTTTGTGTTCCACTTTGGTTGGGTTCGTCCGCCGATTG
CGAATGTTGGCGGTACACCGATTCCACTCGCGCAGTATTTGGCGACGATGGATTGGCGCGCGATTATTTTAATCATCTTC
GTTCTCGCAGCAGCCGTTTGTATGTACTATCCGTTCTTCAAAATGTATGAGAAGAGCTTGATTAAAGAAGAAGAAGTTGT
ATCAGAACGCCAAGCTGCGCACGATGCACTAGACTTGGATTTCTAA

Upstream 100 bases:

>100_bases
GTCATCGATACGAAAGATTACGGCACTGTTAATGGCGCAAACATTTTAAAAGACGCAATTATTCTTAAACTGAACAAATA
AAAAAGTGGAGGGAAACAAC

Downstream 100 bases:

>100_bases
TAAGAAAGGTTGATTTTAAAATGAAATTAATTATTAATGAAAATGAACAACTCGTGGCGCAAACAGTGAGCCAAAGAATC
ATTGAATTGGTAAAAGAAAA

Product: PTS system, Lichenan-specific enzyme IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSSKNKQSFMNRFIAFMEKYFEPVAARIEKQRHISSIKNGMIALISVLIIGSFSLIISAIGNMFPAGSVVKEFFVQNAAA
LNLPFQFTFGLLSIYAAITISYSHAKQMKVPVLHSVMAAVMVTLILNTKMVDGVLNTEFLDSRGLFIAIFAALISVELIG
LFIRKNITIRIKGLPAGIATTFEAIIPLVVLLFSAVGLSILMQSVTSGQIIPEAFTTMLAPAINSIDTPYAVFLICFLEM
LFWFIGLNGYAILIGFVLPFMTQYLGANAAAYAAGEPIPHVFAPNFWDYFMGFSGSGITGALVILALFSKSRELKAVGKV
SVVPAIFTISEPVVFGLPICFNPYLFIPFVLGTPILAVGQWFVFHFGWVRPPIANVGGTPIPLAQYLATMDWRAIILIIF
VLAAAVCMYYPFFKMYEKSLIKEEEVVSERQAAHDALDLDF

Sequences:

>Translated_441_residues
MSSKNKQSFMNRFIAFMEKYFEPVAARIEKQRHISSIKNGMIALISVLIIGSFSLIISAIGNMFPAGSVVKEFFVQNAAA
LNLPFQFTFGLLSIYAAITISYSHAKQMKVPVLHSVMAAVMVTLILNTKMVDGVLNTEFLDSRGLFIAIFAALISVELIG
LFIRKNITIRIKGLPAGIATTFEAIIPLVVLLFSAVGLSILMQSVTSGQIIPEAFTTMLAPAINSIDTPYAVFLICFLEM
LFWFIGLNGYAILIGFVLPFMTQYLGANAAAYAAGEPIPHVFAPNFWDYFMGFSGSGITGALVILALFSKSRELKAVGKV
SVVPAIFTISEPVVFGLPICFNPYLFIPFVLGTPILAVGQWFVFHFGWVRPPIANVGGTPIPLAQYLATMDWRAIILIIF
VLAAAVCMYYPFFKMYEKSLIKEEEVVSERQAAHDALDLDF
>Mature_440_residues
SSKNKQSFMNRFIAFMEKYFEPVAARIEKQRHISSIKNGMIALISVLIIGSFSLIISAIGNMFPAGSVVKEFFVQNAAAL
NLPFQFTFGLLSIYAAITISYSHAKQMKVPVLHSVMAAVMVTLILNTKMVDGVLNTEFLDSRGLFIAIFAALISVELIGL
FIRKNITIRIKGLPAGIATTFEAIIPLVVLLFSAVGLSILMQSVTSGQIIPEAFTTMLAPAINSIDTPYAVFLICFLEML
FWFIGLNGYAILIGFVLPFMTQYLGANAAAYAAGEPIPHVFAPNFWDYFMGFSGSGITGALVILALFSKSRELKAVGKVS
VVPAIFTISEPVVFGLPICFNPYLFIPFVLGTPILAVGQWFVFHFGWVRPPIANVGGTPIPLAQYLATMDWRAIILIIFV
LAAAVCMYYPFFKMYEKSLIKEEEVVSERQAAHDALDLDF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=457, Percent_Identity=29.1028446389497, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 48449; Mature: 48318

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKNKQSFMNRFIAFMEKYFEPVAARIEKQRHISSIKNGMIALISVLIIGSFSLIISAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNMFPAGSVVKEFFVQNAAALNLPFQFTFGLLSIYAAITISYSHAKQMKVPVLHSVMAAV
HCCCCCHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MVTLILNTKMVDGVLNTEFLDSRGLFIAIFAALISVELIGLFIRKNITIRIKGLPAGIAT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
TFEAIIPLVVLLFSAVGLSILMQSVTSGQIIPEAFTTMLAPAINSIDTPYAVFLICFLEM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LFWFIGLNGYAILIGFVLPFMTQYLGANAAAYAAGEPIPHVFAPNFWDYFMGFSGSGITG
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHCCCCCCHHH
ALVILALFSKSRELKAVGKVSVVPAIFTISEPVVFGLPICFNPYLFIPFVLGTPILAVGQ
HHHHHHHHHCCCHHHHHCCHHHHHHHHHCCCCHHHCCHHHHCCHHHHHHHHHCHHHHHHH
WFVFHFGWVRPPIANVGGTPIPLAQYLATMDWRAIILIIFVLAAAVCMYYPFFKMYEKSL
HHHHHHCCCCCCHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKEEEVVSERQAAHDALDLDF
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSKNKQSFMNRFIAFMEKYFEPVAARIEKQRHISSIKNGMIALISVLIIGSFSLIISAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNMFPAGSVVKEFFVQNAAALNLPFQFTFGLLSIYAAITISYSHAKQMKVPVLHSVMAAV
HCCCCCHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MVTLILNTKMVDGVLNTEFLDSRGLFIAIFAALISVELIGLFIRKNITIRIKGLPAGIAT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
TFEAIIPLVVLLFSAVGLSILMQSVTSGQIIPEAFTTMLAPAINSIDTPYAVFLICFLEM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LFWFIGLNGYAILIGFVLPFMTQYLGANAAAYAAGEPIPHVFAPNFWDYFMGFSGSGITG
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHCCCCCCHHH
ALVILALFSKSRELKAVGKVSVVPAIFTISEPVVFGLPICFNPYLFIPFVLGTPILAVGQ
HHHHHHHHHCCCHHHHHCCHHHHHHHHHCCCCHHHCCHHHHCCHHHHHHHHHCHHHHHHH
WFVFHFGWVRPPIANVGGTPIPLAQYLATMDWRAIILIIFVLAAAVCMYYPFFKMYEKSL
HHHHHHCCCCCCHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKEEEVVSERQAAHDALDLDF
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]