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The map label for this gene is artQ [H]

Identifier: 226223465

GI number: 226223465

Start: 885811

End: 887253

Strand: Direct

Name: artQ [H]

Synonym: Lm4b_00863

Alternate gene names: 226223465

Gene position: 885811-887253 (Clockwise)

Preceding gene: 226223464

Following gene: 226223466

Centisome position: 30.41

GC content: 37.35

Gene sequence:

>1443_bases
ATGAAGAAATTTTCACGCTTCATACTAATGATGGCAATCGCTTGTGTTGCCGCATTTATTTTCACAGGAAACGGGTTAAA
TGCAAAAGCTGCGGAAGAAACTTACTTGATTGGTACAGACACAACCTTTGCACCTTTTGAATTTGAGAAAGATGGAGAAC
ATGTCGGAATTGATATGGACATCCTAAAAGCAATTGCAAAAGACCAAAATTTTAAATATGAAATTAAAGCAATGGGATTC
AATGCAGCGGTACAAGCACTAGAAGCTAACCAAGTAGACGGTGTTATCGCTGGGATGAGTATTACAGACGAACGTAAGCA
AAAGTTTGATTTCTCCGATCCATACTTTGATTCTGGTGTCGTTATGGGGATTTTGAAAGATAACGACGAAATCAAAACTT
ACGACGACTTAAAAGGAAAAAAAGTAGCTGTTAAAACAGGTACAGAAGGTTACGCCTTCGCAGAAAAAATCAAAGATAAA
TACGACTTTGATATTGTTGTGTTTGACGACTCAGCTCAAATGTATGACGATGTTAAAACAAGAAATTCTGTAGCATGTTT
TGATGATTATCCCGTACTAGCTTACGGCGTTCAAACAGGTAACGGTTTAAAAATTGTTACTGAGAAAGAAAAAGGAAACT
CCTATGGTTTTGCTGTCAACAAAGGCAAAAATCAAGAACTTTTAGAGAAATTCAATGCTGGATTAGTTAATATTAAAGCA
AGCGGCGAATATGATAAAATTTTAGAAAACTACTTAGGTAAAAATGCGATTAAAGAAAATACAACTGAAAAAGGCTTTAT
GGGAATTATTAAATCTTCTTGGCCAGCACTATTATCCGGTTTGTGGTTGACGATTAGATTAGCCGTAGTTTCGCTAATAA
TCGCCTTCATTATTGGGATTACATTCGGATTTATGAAAGTGAGCAATAGCAAAATCTTGCGCGGGATTGCGACTGTTTAT
GTCGATATCTTCCGTGGAACACCATTAATTGTACAAGCATTCTTCTTCTACTTTGGTATTCCAGCAGCACTTGATTTCAG
GATGCCTGTATTCTTAGCCGGGGTTATCGCGCTAAGCTTGAACGCCGGTGCCTACATGGTCGAAATCGTTCGCGGTGGTA
TTCAATCAGTCGACAAAGGACAAATGGAAGCAGCAAGAAGTCTTGGTTTACCACATAAAAAAGCTATGATGAAAGTTGTT
CTACCGCAAGCAATTCGAATGATGATTCCATCCTTTATTAACCAATTTGTTATCACGCTTAAAGATACATCAATTATGTC
GGCCATTGGACTCGTCGAACTAACACAATCGGGTAAAATCATTATGGCGCGTACATTCGAAAGTACTTGGACATGGCTAA
TCATCGGAATTATGTACCTTATCGTTATTACCATTTTAACGAAAATATCCGATCGTTTAGAAAGGAGATTACGAAATGAC
TAA

Upstream 100 bases:

>100_bases
AATAACCTACCCTTATGGTAAAATCTTACGAGTACGGAAAAAATTTATGCTACATAAAACATTTAATTAAAGTTAAACAC
ATATAGAGGGAGGACACAAT

Downstream 100 bases:

>100_bases
ACTTAAAGTAACTGGACTGAAAAAGAGTTTTGGCGCAAATGAAGTCTTAAAAGGCATTGATATAGAAGTAAAAGAAGGCG
AAGTAGTTTGTGTCATCGGA

Product: Glutamine ABC transporter (binding and transport protein)

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MKKFSRFILMMAIACVAAFIFTGNGLNAKAAEETYLIGTDTTFAPFEFEKDGEHVGIDMDILKAIAKDQNFKYEIKAMGF
NAAVQALEANQVDGVIAGMSITDERKQKFDFSDPYFDSGVVMGILKDNDEIKTYDDLKGKKVAVKTGTEGYAFAEKIKDK
YDFDIVVFDDSAQMYDDVKTRNSVACFDDYPVLAYGVQTGNGLKIVTEKEKGNSYGFAVNKGKNQELLEKFNAGLVNIKA
SGEYDKILENYLGKNAIKENTTEKGFMGIIKSSWPALLSGLWLTIRLAVVSLIIAFIIGITFGFMKVSNSKILRGIATVY
VDIFRGTPLIVQAFFFYFGIPAALDFRMPVFLAGVIALSLNAGAYMVEIVRGGIQSVDKGQMEAARSLGLPHKKAMMKVV
LPQAIRMMIPSFINQFVITLKDTSIMSAIGLVELTQSGKIIMARTFESTWTWLIIGIMYLIVITILTKISDRLERRLRND

Sequences:

>Translated_480_residues
MKKFSRFILMMAIACVAAFIFTGNGLNAKAAEETYLIGTDTTFAPFEFEKDGEHVGIDMDILKAIAKDQNFKYEIKAMGF
NAAVQALEANQVDGVIAGMSITDERKQKFDFSDPYFDSGVVMGILKDNDEIKTYDDLKGKKVAVKTGTEGYAFAEKIKDK
YDFDIVVFDDSAQMYDDVKTRNSVACFDDYPVLAYGVQTGNGLKIVTEKEKGNSYGFAVNKGKNQELLEKFNAGLVNIKA
SGEYDKILENYLGKNAIKENTTEKGFMGIIKSSWPALLSGLWLTIRLAVVSLIIAFIIGITFGFMKVSNSKILRGIATVY
VDIFRGTPLIVQAFFFYFGIPAALDFRMPVFLAGVIALSLNAGAYMVEIVRGGIQSVDKGQMEAARSLGLPHKKAMMKVV
LPQAIRMMIPSFINQFVITLKDTSIMSAIGLVELTQSGKIIMARTFESTWTWLIIGIMYLIVITILTKISDRLERRLRND
>Mature_480_residues
MKKFSRFILMMAIACVAAFIFTGNGLNAKAAEETYLIGTDTTFAPFEFEKDGEHVGIDMDILKAIAKDQNFKYEIKAMGF
NAAVQALEANQVDGVIAGMSITDERKQKFDFSDPYFDSGVVMGILKDNDEIKTYDDLKGKKVAVKTGTEGYAFAEKIKDK
YDFDIVVFDDSAQMYDDVKTRNSVACFDDYPVLAYGVQTGNGLKIVTEKEKGNSYGFAVNKGKNQELLEKFNAGLVNIKA
SGEYDKILENYLGKNAIKENTTEKGFMGIIKSSWPALLSGLWLTIRLAVVSLIIAFIIGITFGFMKVSNSKILRGIATVY
VDIFRGTPLIVQAFFFYFGIPAALDFRMPVFLAGVIALSLNAGAYMVEIVRGGIQSVDKGQMEAARSLGLPHKKAMMKVV
LPQAIRMMIPSFINQFVITLKDTSIMSAIGLVELTQSGKIIMARTFESTWTWLIIGIMYLIVITILTKISDRLERRLRND

Specific function: Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=209, Percent_Identity=38.755980861244, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1787031, Length=232, Percent_Identity=37.0689655172414, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788226, Length=212, Percent_Identity=34.4339622641509, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786874, Length=215, Percent_Identity=33.953488372093, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786873, Length=217, Percent_Identity=29.9539170506912, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788228, Length=268, Percent_Identity=30.9701492537313, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787086, Length=211, Percent_Identity=31.2796208530806, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787085, Length=246, Percent_Identity=31.7073170731707, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787087, Length=225, Percent_Identity=31.1111111111111, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788645, Length=224, Percent_Identity=30.3571428571429, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI87082239, Length=213, Percent_Identity=30.5164319248826, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788646, Length=222, Percent_Identity=27.9279279279279, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787088, Length=251, Percent_Identity=29.8804780876494, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788649, Length=236, Percent_Identity=30.9322033898305, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788648, Length=225, Percent_Identity=28.8888888888889, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI48994930, Length=115, Percent_Identity=40, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 53272; Mature: 53272

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFSRFILMMAIACVAAFIFTGNGLNAKAAEETYLIGTDTTFAPFEFEKDGEHVGIDMD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCEECCCHH
ILKAIAKDQNFKYEIKAMGFNAAVQALEANQVDGVIAGMSITDERKQKFDFSDPYFDSGV
HHHHHHCCCCCEEEEEEECHHHHHHHHHCCCCCCEEECCCCCHHHHHCCCCCCCCCCCCE
VMGILKDNDEIKTYDDLKGKKVAVKTGTEGYAFAEKIKDKYDFDIVVFDDSAQMYDDVKT
EEEEEECCCCCCCHHCCCCCEEEEEECCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHC
RNSVACFDDYPVLAYGVQTGNGLKIVTEKEKGNSYGFAVNKGKNQELLEKFNAGLVNIKA
CCCEEEECCCCEEEEEEECCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHCCCEEEEEC
SGEYDKILENYLGKNAIKENTTEKGFMGIIKSSWPALLSGLWLTIRLAVVSLIIAFIIGI
CCCHHHHHHHHHCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFGFMKVSNSKILRGIATVYVDIFRGTPLIVQAFFFYFGIPAALDFRMPVFLAGVIALSL
HHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHC
NAGAYMVEIVRGGIQSVDKGQMEAARSLGLPHKKAMMKVVLPQAIRMMIPSFINQFVITL
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
KDTSIMSAIGLVELTQSGKIIMARTFESTWTWLIIGIMYLIVITILTKISDRLERRLRND
CCHHHHHHHHHHEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKFSRFILMMAIACVAAFIFTGNGLNAKAAEETYLIGTDTTFAPFEFEKDGEHVGIDMD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCEECCCHH
ILKAIAKDQNFKYEIKAMGFNAAVQALEANQVDGVIAGMSITDERKQKFDFSDPYFDSGV
HHHHHHCCCCCEEEEEEECHHHHHHHHHCCCCCCEEECCCCCHHHHHCCCCCCCCCCCCE
VMGILKDNDEIKTYDDLKGKKVAVKTGTEGYAFAEKIKDKYDFDIVVFDDSAQMYDDVKT
EEEEEECCCCCCCHHCCCCCEEEEEECCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHC
RNSVACFDDYPVLAYGVQTGNGLKIVTEKEKGNSYGFAVNKGKNQELLEKFNAGLVNIKA
CCCEEEECCCCEEEEEEECCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHCCCEEEEEC
SGEYDKILENYLGKNAIKENTTEKGFMGIIKSSWPALLSGLWLTIRLAVVSLIIAFIIGI
CCCHHHHHHHHHCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFGFMKVSNSKILRGIATVYVDIFRGTPLIVQAFFFYFGIPAALDFRMPVFLAGVIALSL
HHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHC
NAGAYMVEIVRGGIQSVDKGQMEAARSLGLPHKKAMMKVVLPQAIRMMIPSFINQFVITL
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
KDTSIMSAIGLVELTQSGKIIMARTFESTWTWLIIGIMYLIVITILTKISDRLERRLRND
CCHHHHHHHHHHEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]