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The map label for this gene is bglK [H]

Identifier: 226223394

GI number: 226223394

Start: 801162

End: 802028

Strand: Reverse

Name: bglK [H]

Synonym: Lm4b_00792

Alternate gene names: 226223394

Gene position: 802028-801162 (Counterclockwise)

Preceding gene: 226223397

Following gene: 226223391

Centisome position: 27.54

GC content: 42.45

Gene sequence:

>867_bases
ATGACGATACTTGCATTTGATTTAGGTGGAACAGCAGTGAAGTTTGGCGTGTTAACAACAGCTGGAGAAATTCTAGAAAA
AGGTAAATTCAAAACCCCGGATAATTTGGATGAAATGCTGCAATCGCTTATGGATGTAAAAGCAAATTACGATTATACAT
TACAAGGAGCTGCGTTTAGTTGTCCAGGTGCGGTTAATAATGAAACCGGTATCATTGGCGGCGCGAGTGCTATCCCCTAC
ATACATAATTTCCCTTTTAAACAATTACTTGAAGAAAAACTGGGGCTTCCTGTTACGATGGAAAATGACGCCAACTGTGC
AGCTTTAGCAGAGGTTTGGATTGGCGCGGCGAAAGACAAGCAAGATATTATTTTTATGATTCTTGGAAGTGGAGTTGGTG
GCGCAGTTATTCGCGGTGGCAAGGTACATCACGGGGCCAATTTGCATGGTGGTGAATTTGGTTATATGTTGATGGACCGC
GACGGACGCACACTTAGCGAGCTTGGTACAGTCGTAAATGCTGCGACGAGAATAGCCGAGCGTTTAGAAGTTCCAAAAGC
TAGTATAGACGGTCTTCGGGCATTTGAATTACGTGCGGAAGGAAATAAAATCGCAAAAGAAGAGCTAGATACGATGTTTT
ATTATCTTGCGAGAAGTATTTTTAATTTGCAGTACACACTTGATCCTGAACTAGTCGTCATTGGTGGTGGTGTAAGTGAG
CGGGCTGATTTTATTCAAGAGTTGACCGAATATGTGGCGAAAGTAAAAGCGTCTGTACCAATTGCGACTATTAGCCCTAC
TGTTGTTGGCTGTCACTTTGGAAATGATGCCAATCTCATTGGTGCAACTGCATTTCATTTAGCATAA

Upstream 100 bases:

>100_bases
GACGTTAATTTTTAGCAAAGTATTTTCACTTTTTATTTGTCATTTGTATTGTTTAAAAGTATGATAAGTATATACTTTTC
TATAAAAAGGAGATTGAGTA

Downstream 100 bases:

>100_bases
AAAAGAAGCTGGTCACTTTTTTCGTGCCAGCTTCTTTCTATCCTAATTTTTCTGATTCACCGCGGCTTTCTAATACTTCA
GAAACTGCTTCCAGCCACTT

Product: transcription regulator (repressor)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MTILAFDLGGTAVKFGVLTTAGEILEKGKFKTPDNLDEMLQSLMDVKANYDYTLQGAAFSCPGAVNNETGIIGGASAIPY
IHNFPFKQLLEEKLGLPVTMENDANCAALAEVWIGAAKDKQDIIFMILGSGVGGAVIRGGKVHHGANLHGGEFGYMLMDR
DGRTLSELGTVVNAATRIAERLEVPKASIDGLRAFELRAEGNKIAKEELDTMFYYLARSIFNLQYTLDPELVVIGGGVSE
RADFIQELTEYVAKVKASVPIATISPTVVGCHFGNDANLIGATAFHLA

Sequences:

>Translated_288_residues
MTILAFDLGGTAVKFGVLTTAGEILEKGKFKTPDNLDEMLQSLMDVKANYDYTLQGAAFSCPGAVNNETGIIGGASAIPY
IHNFPFKQLLEEKLGLPVTMENDANCAALAEVWIGAAKDKQDIIFMILGSGVGGAVIRGGKVHHGANLHGGEFGYMLMDR
DGRTLSELGTVVNAATRIAERLEVPKASIDGLRAFELRAEGNKIAKEELDTMFYYLARSIFNLQYTLDPELVVIGGGVSE
RADFIQELTEYVAKVKASVPIATISPTVVGCHFGNDANLIGATAFHLA
>Mature_287_residues
TILAFDLGGTAVKFGVLTTAGEILEKGKFKTPDNLDEMLQSLMDVKANYDYTLQGAAFSCPGAVNNETGIIGGASAIPYI
HNFPFKQLLEEKLGLPVTMENDANCAALAEVWIGAAKDKQDIIFMILGSGVGGAVIRGGKVHHGANLHGGEFGYMLMDRD
GRTLSELGTVVNAATRIAERLEVPKASIDGLRAFELRAEGNKIAKEELDTMFYYLARSIFNLQYTLDPELVVIGGGVSER
ADFIQELTEYVAKVKASVPIATISPTVVGCHFGNDANLIGATAFHLA

Specific function: Catalyzes the ATP-dependent phosphorylation of a wide variety of beta-D-glucosides, to produce 6-phospho-beta-D- glucosides including cellobiose-6'-P, gentiobiose-6'-P, cellobiitol-6-P, salicin-6-P, and arbutin-6-P. Is not able to phosphorylate alpha-D-gl

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=263, Percent_Identity=26.9961977186312, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI298566325, Length=263, Percent_Identity=26.9961977186312, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4885285, Length=263, Percent_Identity=26.9961977186312, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI190014632, Length=263, Percent_Identity=26.9961977186312, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1787363, Length=301, Percent_Identity=27.5747508305648, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI87081733, Length=269, Percent_Identity=26.0223048327138, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787878, Length=245, Percent_Identity=22.0408163265306, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082230, Length=269, Percent_Identity=28.2527881040892, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.85 [H]

Molecular weight: Translated: 30804; Mature: 30672

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILAFDLGGTAVKFGVLTTAGEILEKGKFKTPDNLDEMLQSLMDVKANYDYTLQGAAFS
CEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCEEE
CPGAVNNETGIIGGASAIPYIHNFPFKQLLEEKLGLPVTMENDANCAALAEVWIGAAKDK
CCCCCCCCCCEEECCCCCCHHCCCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCCC
QDIIFMILGSGVGGAVIRGGKVHHGANLHGGEFGYMLMDRDGRTLSELGTVVNAATRIAE
CCEEEEEECCCCCCCEEECCEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
RLEVPKASIDGLRAFELRAEGNKIAKEELDTMFYYLARSIFNLQYTLDPELVVIGGGVSE
HHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCCHH
RADFIQELTEYVAKVKASVPIATISPTVVGCHFGNDANLIGATAFHLA
HHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEECCCCCEEECCHHHCC
>Mature Secondary Structure 
TILAFDLGGTAVKFGVLTTAGEILEKGKFKTPDNLDEMLQSLMDVKANYDYTLQGAAFS
EEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCEEE
CPGAVNNETGIIGGASAIPYIHNFPFKQLLEEKLGLPVTMENDANCAALAEVWIGAAKDK
CCCCCCCCCCEEECCCCCCHHCCCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCCC
QDIIFMILGSGVGGAVIRGGKVHHGANLHGGEFGYMLMDRDGRTLSELGTVVNAATRIAE
CCEEEEEECCCCCCCEEECCEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
RLEVPKASIDGLRAFELRAEGNKIAKEELDTMFYYLARSIFNLQYTLDPELVVIGGGVSE
HHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCCHH
RADFIQELTEYVAKVKASVPIATISPTVVGCHFGNDANLIGATAFHLA
HHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEECCCCCEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12110692 [H]