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The map label for this gene is yhcG [H]

Identifier: 226223366

GI number: 226223366

Start: 774392

End: 775081

Strand: Direct

Name: yhcG [H]

Synonym: Lm4b_00764

Alternate gene names: 226223366

Gene position: 774392-775081 (Clockwise)

Preceding gene: 226223365

Following gene: 226223367

Centisome position: 26.59

GC content: 34.93

Gene sequence:

>690_bases
ATGTTAGTGGGAAATAATATCGCTAAATCCTATCCAAATAAATTAGTCTTACAAAATGTAGACCTCGAAGCAAAACCAGG
CGACATGATCGTGCTCACTGGTGAAAATGGTAGCGGGAAAACGACCTTGCTAGATATGTTAGCAAGCTTGAAGAAACCGG
ATAGTGGCACATTGGAATTAGACAATGAAGTATTTACTACTAATGATATCCGCCAGCAAATCGCTTATTTAAATAATGAA
CTTTACGCTAAAAAAAGTACTACTATAGAAGATTATATGAAACAACATGGTTTGCTTTTTGAAAATATGGAGTTAGATAA
GTGGGACCGATTACTTGCTGGATGGCGAATTAACAAACGACTAAAACTTGGCGAACTATCAACAGGTATGTTAATGAAAG
TGAAAATTGGTAGTGTGTTAGCAAGAAAAGCCAAATTGTATCTTTATGATGAACCTTTTGCGAGTATCGATATTATGGCT
CGTTCAGAAGTAATGAAAGCTATTATTAGCGAAACAAATCCAGATGCTATCACGATTATTTCTTCCCACCATTTAGAAGG
AACCGAAAAATTATATAGCAAACTGTGGTTAATTAAAGATAACACGTTAAAAACTATTGAAACAGAAACTTATCGCGAGG
AAACAGGCAACGCATTAATCGATTTCTATAAGGAGGAAATGAACAAATGA

Upstream 100 bases:

>100_bases
AAACAACTTACCGAAAATTTTATTAGTGAAATGAGTAAATTAGGAATTAATAAAGAAAAAATTATCGCTTGGGTGAAAAA
AGTAGAGGAGGTAGAAGTAA

Downstream 100 bases:

>100_bases
CAAAAATGATTACTTTTTATTTAAAACAAATCAGTCCTATTCTTTTGATTGGACTTGCAATTATCTTGGGGCTGAACTTT
CTGGGGTTCACGATGAATCT

Product: ABC transporter, ATP-binding protein

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MLVGNNIAKSYPNKLVLQNVDLEAKPGDMIVLTGENGSGKTTLLDMLASLKKPDSGTLELDNEVFTTNDIRQQIAYLNNE
LYAKKSTTIEDYMKQHGLLFENMELDKWDRLLAGWRINKRLKLGELSTGMLMKVKIGSVLARKAKLYLYDEPFASIDIMA
RSEVMKAIISETNPDAITIISSHHLEGTEKLYSKLWLIKDNTLKTIETETYREETGNALIDFYKEEMNK

Sequences:

>Translated_229_residues
MLVGNNIAKSYPNKLVLQNVDLEAKPGDMIVLTGENGSGKTTLLDMLASLKKPDSGTLELDNEVFTTNDIRQQIAYLNNE
LYAKKSTTIEDYMKQHGLLFENMELDKWDRLLAGWRINKRLKLGELSTGMLMKVKIGSVLARKAKLYLYDEPFASIDIMA
RSEVMKAIISETNPDAITIISSHHLEGTEKLYSKLWLIKDNTLKTIETETYREETGNALIDFYKEEMNK
>Mature_229_residues
MLVGNNIAKSYPNKLVLQNVDLEAKPGDMIVLTGENGSGKTTLLDMLASLKKPDSGTLELDNEVFTTNDIRQQIAYLNNE
LYAKKSTTIEDYMKQHGLLFENMELDKWDRLLAGWRINKRLKLGELSTGMLMKVKIGSVLARKAKLYLYDEPFASIDIMA
RSEVMKAIISETNPDAITIISSHHLEGTEKLYSKLWLIKDNTLKTIETETYREETGNALIDFYKEEMNK

Specific function: Part Of The Binding-Protein-Dependent Transport System For Glutamine. Probably Responsible For Energy Coupling To The Transport System. [C]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27881501, Length=225, Percent_Identity=24.8888888888889, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI30795238, Length=225, Percent_Identity=24.8888888888889, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1787029, Length=213, Percent_Identity=31.4553990610329, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788225, Length=210, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788165, Length=155, Percent_Identity=27.741935483871, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789593, Length=220, Percent_Identity=25.9090909090909, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1786345, Length=192, Percent_Identity=26.0416666666667, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081791, Length=191, Percent_Identity=26.1780104712042, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788210, Length=208, Percent_Identity=25.9615384615385, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790739, Length=195, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789991, Length=211, Percent_Identity=26.5402843601896, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787105, Length=198, Percent_Identity=26.7676767676768, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789672, Length=196, Percent_Identity=23.469387755102, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786253, Length=183, Percent_Identity=25.6830601092896, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48995001, Length=211, Percent_Identity=24.1706161137441, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1786563, Length=218, Percent_Identity=24.3119266055046, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI87081709, Length=167, Percent_Identity=27.5449101796407, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1787370, Length=241, Percent_Identity=25.3112033195021, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788472, Length=221, Percent_Identity=23.9819004524887, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=219, Percent_Identity=25.5707762557078, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666092, Length=212, Percent_Identity=27.3584905660377, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643674, Length=227, Percent_Identity=25.5506607929515, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007328, Length=205, Percent_Identity=25.3658536585366, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574150, Length=205, Percent_Identity=25.3658536585366, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221512771, Length=232, Percent_Identity=25, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26043; Mature: 26043

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVGNNIAKSYPNKLVLQNVDLEAKPGDMIVLTGENGSGKTTLLDMLASLKKPDSGTLEL
CCCCCCHHHHCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEE
DNEVFTTNDIRQQIAYLNNELYAKKSTTIEDYMKQHGLLFENMELDKWDRLLAGWRINKR
CCEEECHHHHHHHHHHHCCHHEECCCCCHHHHHHHCCCEEECCCCCHHHHHHHCCEECCE
LKLGELSTGMLMKVKIGSVLARKAKLYLYDEPFASIDIMARSEVMKAIISETNPDAITII
EEECCCCCCEEEEEEHHHHHHHHEEEEEEECCCCCEEHHHHHHHHHHHHHCCCCCEEEEE
SSHHLEGTEKLYSKLWLIKDNTLKTIETETYREETGNALIDFYKEEMNK
ECCCCCHHHHHHHHEEEEECCCEEEEEHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MLVGNNIAKSYPNKLVLQNVDLEAKPGDMIVLTGENGSGKTTLLDMLASLKKPDSGTLEL
CCCCCCHHHHCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEE
DNEVFTTNDIRQQIAYLNNELYAKKSTTIEDYMKQHGLLFENMELDKWDRLLAGWRINKR
CCEEECHHHHHHHHHHHCCHHEECCCCCHHHHHHHCCCEEECCCCCHHHHHHHCCEECCE
LKLGELSTGMLMKVKIGSVLARKAKLYLYDEPFASIDIMARSEVMKAIISETNPDAITII
EEECCCCCCEEEEEEHHHHHHHHEEEEEEECCCCCEEHHHHHHHHHHHHHCCCCCEEEEE
SSHHLEGTEKLYSKLWLIKDNTLKTIETETYREETGNALIDFYKEEMNK
ECCCCCHHHHHHHHEEEEECCCEEEEEHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]